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CREATINE PHOSPHATE DISODIUM SALT HEXAHYDRATE

Product Name
CREATINE PHOSPHATE DISODIUM SALT HEXAHYDRATE
CAS No.
19333-65-4
Chemical Name
CREATINE PHOSPHATE DISODIUM SALT HEXAHYDRATE
Synonyms
PHOSPHOCREATINE DISODIUM HYDRATE;Disodium N-phosphocreatine hydrate;PHOSPHOCREATINE DISODIUM SALT, HYDRATE;Phosphocreatine hydrate disodium salt;N-(PHOSPHONOAMIDINO)SARCOSINE ISODIUM SALT;CREATINE PHOSPHATE DISODIUM SALT 4-HYDRATE;Phosphocreatine disodium salt hydrate >=97%;CREATINE PHOSPHATE DISODIUM SALT HEXAHYDRATE;phosphocreatine disodium synthetic*preweighed via;N-(phosphonoamidino)sarcosine disodium salt hydrate
CBNumber
CB9148161
Molecular Formula
C4H20N3Na2O11P
Formula Weight
363.17
MOL File
19333-65-4.mol
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CREATINE PHOSPHATE DISODIUM SALT HEXAHYDRATE Property

storage temp. 
-20°C
solubility 
PBS (pH 7.2): 10 mg/ml
form 
White crystalline
color 
White to off-white
Water Solubility 
water: 50mg/mL, clear, colorless
CAS DataBase Reference
19333-65-4(CAS DataBase Reference)
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
2380
Product name
Creatine Phosphate, Disodium Salt - CAS 19333-65-4 - Calbiochem
Purity
Creatine Phosphate, Disodium Salt, CAS 19333-65-4, is a high-energy phosphate compound that stores energy from mitochondria whenever sufficient amounts of ATP are present.
Packaging
5G
Price
$85.1
Updated
2025/07/31
Sigma-Aldrich
Product number
2380
Product name
Creatine Phosphate, Disodium Salt - CAS 19333-65-4 - Calbiochem
Purity
Creatine Phosphate, Disodium Salt, CAS 19333-65-4, is a high-energy phosphate compound that stores energy from mitochondria whenever sufficient amounts of ATP are present.
Packaging
25g
Price
$359
Updated
2025/07/31
Sigma-Aldrich
Product number
P7936
Product name
Phosphocreatine disodium salt hydrate
Purity
≥97%
Packaging
10mg
Price
$34.76
Updated
2025/07/31
Sigma-Aldrich
Product number
P7936
Product name
Phosphocreatine disodium salt hydrate
Purity
≥97%
Packaging
1g
Price
$118
Updated
2025/07/31
Sigma-Aldrich
Product number
P7936
Product name
Phosphocreatine disodium salt hydrate
Purity
≥97%
Packaging
5g
Price
$233
Updated
2025/07/31
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CREATINE PHOSPHATE DISODIUM SALT HEXAHYDRATE Chemical Properties,Usage,Production

Chemical Properties

Crystalline

Uses

Phosphocreatine disodium salt hydrate has been used:

  • as a component: of Xenopus buffer (XB) buffer to remove the membrane-bound proteins
  • of M5+?buffer to perform polarized total internal reflection fluorescence (polTIRF) experiments
  • of ATP regenerating system for 7-nitro-2-1,3-benzoxadiazol-4-yl phospholipid(NBD-PL) translocation assay

General Description

Creatine phosphate is a high-energy phosphate compound that stores energy from mitochondria whenever sufficient amounts of ATP are present. When ATP levels are low, energy from phosphocreatine is transferred to ADP molecules, which are quickly converted to ATP. It is often a component of ATP-generating systems.

Biochem/physiol Actions

Phosphocreatine is widely known for its quickest form of regeneration using enzyme creatine kinase. It functions as a temporal energy buffer. Phosphocreatine is present in muscle tissues and plays a major role in maintaining energy homeostasis in muscle cells.

in vivo

Non-salt form:
Phosphocreatine (200 mg/kg, i.p., once every other day, 7 weeks) not only alleviates oxidative stress and myocardial apoptosis, but also rescues myocardial necroptosis in DOX-induced cardiotoxicity of rat[2].
Phosphocreatine (20-40 mg/kg, i.v., daily, 6 weeks) has a protective effect on the kidney tissues against diabetic nephropathy in SD (Sprague Dawley) rats[4].

Animal Model:Male Sprague Dawley (SD) rats, i.p., normal saline, 3 times; i.p., DOX 2 mg/kg, 7 times; i.p., normal saline, 3 times [2]
Dosage:200 mg/kg
Administration:i.p., once every other day, 7 weeks
Result:Improved the heart function abnormality.
Lowered myocardial apoptosis.
Recovered the expression of Nrf2, SOD, FoxO3a and diminished C-Casp3, Bax/Bcl2 in the myocardial tissue of rats.
Markedly improved myocardial necroptosis, as indicated by decreasing expression of RIP3 and CaMKII.
Increased expression level of TAK1.
Animal Model:Male Sprague Dawley (SD) rats, i.p., 70 mg/kg (STZ(Streptozotocin) (HY-13753)), daily, 6 weeks [4]
Dosage:20, 40 mg/kg
Administration:i.p., daily, 6 weeks
Result:Reduced hyperglycemia compared with STZ (Streptozotocin) (HY-13753) -treated rats.
Increased the weight of rats gradually compared with STZ (Streptozotocin) (HY-13753) group.
Decreased kidney weight index (kidney weight/body weight).
Decreased MDA level and increased of GSH and SOD levels compared with STZ group.
Decreased the apoptotic rate compared with MGO-treated groups.

IC 50

Human Endogenous Metabolite

CREATINE PHOSPHATE DISODIUM SALT HEXAHYDRATE Preparation Products And Raw materials

Raw materials

Preparation Products

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CREATINE PHOSPHATE DISODIUM SALT HEXAHYDRATE Suppliers

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View Lastest Price from CREATINE PHOSPHATE DISODIUM SALT HEXAHYDRATE manufacturers

Hebei Chuanghai Biotechnology Co,.LTD
Product
CREATINE PHOSPHATE DISODIUM SALT HEXAHYDRATE 19333-65-4
Price
US $30.00-10.00/kg
Min. Order
10kg
Purity
99%
Supply Ability
100000kg
Release date
2024-08-14
Career Henan Chemical Co
Product
CREATINE PHOSPHATE DISODIUM SALT HEXAHYDRATE 19333-65-4
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2020-02-13

19333-65-4, CREATINE PHOSPHATE DISODIUM SALT HEXAHYDRATERelated Search:


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