Ethyl 2-amino-3-cyclobutylpropanoate

Product Name: Ethyl 2-amino-3-cyclobutylpropanoate
CAS No.: 394735-17-2
Chemical Name: Ethyl 2-amino-3-cyclobutylpropanoate
Synonyms: Ethyl 3-cyclobutylalaninate;3-Cyclobutylalanine ethyl etser;Ethyl 2-amino-3-cyclobutylpropanoate;2-amino-3-cyclobutylpropanoic acid ethyl ester;Cyclobutanepropanoicacid, a-amino-, ethyl ester;2-AMino-3-cyclobutyl-propionic acid ethyl ester;Cyclobutanepropanoic acid, α-amino-, ethyl ester
CBNumber: CB91482037
Molecular Formula: C9H17NO2
Formula Weight: 171.24
MOL File: 394735-17-2.mol

More

Less

Ethyl 2-amino-3-cyclobutylpropanoate Property

Boiling point:: 227.8±13.0 °C(Predicted)
Density: 1.034
storage temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
form: Liquid
pka: 8.11±0.33(Predicted)

More

Less

Safety

HS Code: 2922498590

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

TRC

Product number: E899928
Product name: Ethyl2-amino-3-cyclobutylpropanoate
Packaging: 50mg
Price: $90
Updated: 2021/12/16

TRC

Product number: E899928
Product name: Ethyl2-amino-3-cyclobutylpropanoate
Packaging: 100mg
Price: $130
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: AAA0010808
Product name: ETHYL 2-AMINO-3-CYCLOBUTYLPROPANOATE
Purity: 95.00%
Packaging: 5MG
Price: $501.18
Updated: 2021/12/16

AK Scientific

Product number: 5159AB
Product name: Ethyl2-amino-3-cyclobutylpropanoate
Packaging: 5g
Price: $651
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: AAA0010808
Product name: ETHYL 2-AMINO-3-CYCLOBUTYLPROPANOATE
Purity: 95.00%
Packaging: 0.25G
Price: $670
Updated: 2021/12/16

More

Less

Ethyl 2-amino-3-cyclobutylpropanoate Chemical Properties,Usage,Production

Synthesis

17247-58-4

69555-14-2

394735-17-2

Example-1: Preparation of ethyl 2-amino-3-cyclobutylpropionate (formula-4a) Ethyl 2-(diphenylmethyleneamino) acetate (Formula-A3, 250 g) was dissolved in tetrahydrofuran (2000 mL) and the mixture was cooled to 0-5°C. Potassium tert-butoxide (157.4 g) was slowly added at a temperature below 10°C and stirred at 0-5°C for 1 hour. Subsequently, bromomethylcyclobutane (185 g) was slowly added over 30 minutes at 0-5 °C. The reaction mixture was warmed to 25-30 °C and stirring was continued for 30 hours. After completion of the reaction, 2N hydrochloric acid was added to the reaction mixture and stirred for 6 hours. Dichloromethane was added and after stirring for 15 minutes, the organic and aqueous layers were separated. The aqueous layer was washed with dichloromethane. Dichloromethane was added to the aqueous layer and cooled to 0-5°C. The pH of the reaction mixture was adjusted to 12.5 with 50% sodium hydroxide solution, stirred for 10 minutes and the organic and aqueous layers were separated again. The aqueous layer was extracted with dichloromethane at 0-5°C. All organic layers were combined, dried with anhydrous sodium sulfate and the solvent was removed by distillation under reduced pressure to give the target product ethyl 2-amino-3-cyclobutylpropionate. Yield: 45 g.

References

[1] Letters in Organic Chemistry, 2016, vol. 13, # 5, p. 352 - 358
[2] Patent: WO2005/85197, 2005, A1. Location in patent: Page/Page column 58-59
[3] Patent: US2006/276407, 2006, A1. Location in patent: Page/Page column 410
[4] Patent: US2006/281688, 2006, A1. Location in patent: Page/Page column 622
[5] Patent: WO2014/61034, 2014, A1. Location in patent: Page/Page column 9; 27; 35

Ethyl 2-amino-3-cyclobutylpropanoate Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Ethyl 2-amino-3-cyclobutylpropanoate Suppliers

China 37 India 2 United States 5 Global 44

Candia Thamtech Company Limited

Tel: 0371-86615086 18203638366 0371-86159066 13526786601
Fax: 0371-86159066
Country: China
ProdList: 2015
Advantage: 60

SynAsst Chemical.

Tel: 021-60343070
Fax: 021-35122006
Country: China
ProdList: 12740
Advantage: 55

shanghai cooperpharm co.,LTD .

Tel: +86-021-58975553
Fax: +86-021-58975554
Email: sales@cooperpharm.com
Country: China
ProdList: 1210
Advantage: 56

Porse Fine Chemical Co.,LTD

Tel: 20-66003216 18666003216
Fax: +86-20-28069063
Email: info@porsefinechemical.com
Country: China
ProdList: 1941
Advantage: 62

Shanghai XR Chemical Technology Co., Ltd.

Tel: 021-31007982 18019432809
Fax: 021-31007982
Email: info@xrpharma.com
Country: China
ProdList: 676
Advantage: 55

Credit Asia Chemical Co., Ltd.

Tel: +86 (21) 61124340
Fax: +86 (21) 6129-4103
Country: China
ProdList: 9756
Advantage: 58

Lanzhou HuaHao Pharmaceutical Co., Ltd.

Tel: 18189674620
Email: 761137152@qq.com
Country: China
ProdList: 489
Advantage: 55

ShangHai Wisacheam Pharmaceutical Co., Ltd.

Tel: 13817485796
Fax: QQ:895624079
Email: tim@wisacheampharm.com
Country: China
ProdList: 3593
Advantage: 58

Suzhou Shang Enda Biotechnology Ltd.

Tel: 0512-66242155 13382105697
Fax: 0512-66242155
Email: sedswkj@163.com
Country: China
ProdList: 39
Advantage: 55

ShangHai Biochempartner Co.,Ltd

Tel: 177-54423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8000
Advantage: 62

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Capot Chemical Co.,Ltd.

Tel: +86-（0）57185586718; +8613336195806
Fax: +86-571-85864795
Email: sales@capot.com
Country: China
ProdList: 29735
Advantage: 60

Aikon International Limited

Tel: 025-66113011 13155353615
Fax: (7)02557626880
Email: qzhang@aikonchem.com
Country: China
ProdList: 15394
Advantage: 58

Nanjing crow LuNing pharmaceutical technology co., LTD

Tel: 13382066392
Country: CHINA
ProdList: 4877
Advantage: 58

Chengdu Feibai Pharmaceutical Co., Ltd.

Tel: 028-84641798 18782128315
Email: 3302391190@qq.com
Country: China
ProdList: 9800
Advantage: 55

Shanghai zhigan biotechnology co., LTD

Tel
Email: zhiqianbio@126.com
Country: China
ProdList: 19778
Advantage: 58

Labnetwork lnc.

Tel: +86-27-50766799 +8618062016861
Email: contact@labnetwork.com
Country: China
ProdList: 19987
Advantage: 58

Nextpeptide Inc

Tel: +86-0571-81612335 +8613336028439
Email: sales@nextpeptide.com
Country: China
ProdList: 19908
Advantage: 58

Zhejiang Lianshuo Biotechnology Co., Ltd.

Tel: 18616526224
Email: lianshuo@vip.126.com
Country: China
ProdList: 9607
Advantage: 58

Block Chemical Technology (Shanghai) Co., LTD

Tel: 021-20432219 13918097649
Fax: QQ79021576
Email: li_jinfei@acblock-lab.com
Country: China
ProdList: 9673
Advantage: 58

Jiangsu Hongmin Pharmaceutical Co., Ltd.

Tel: 18221292452
Email: fannieliu@glschina.com
Country: China
ProdList: 6798
Advantage: 58

career henan chemical co

Tel: +86-0371-86658258 +8613203830695
Fax: 0086-371-86658258
Email: factory@coreychem.com
Country: China
ProdList: 29798
Advantage: 58

Guangzhou Yuheng Pharmaceutical Technology Co., Ltd

Tel: +8613580539051
Email: joe@yuhengpharm.com
Country: CHINA
ProdList: 21142
Advantage: 58

Wuhan Topule

Tel: +86-02787215551 +86-19945035818
Fax: 027-87215551
Email: 2936752263@qq.com
Country: China
ProdList: 7985
Advantage: 58

Jiaxing Zhejia Biotechnology Co., LTD

Tel: 0573-85609002 18367600069;
Email: zhejia01@163.com
Country: China
ProdList: 8887
Advantage: 58

Wuhan Yingnuo Pharmaceutical Technology Co., Ltd.

Tel: 15387063101
Email: 2881924050@qq.com
Country: China
ProdList: 9958
Advantage: 58

Shanghai Haohong Scientific Co., Ltd.

Tel: 400-8210725 4008210725
Email: malulu@leyan.com
Country: China
ProdList: 40000
Advantage: 58

Lianhe Aigen Pharmatech Co.,Ltd.

Tel: 18918657159
Email: sales-Aigen@lianhetech.com
Country: China
ProdList: 3000
Advantage: 58

XIAMEN AMITY INDUSTRY AND TRADE CO., LTD.

Tel: +8618950047208
Email: ellena@amitychem.com
Country: China
ProdList: 43416
Advantage: 58

SHANGHAI KEAN TECHNOLOGY CO., LTD.

Tel: +8613817748580
Fax: 021-50175322
Email: cooperation@kean-chem.com
Country: China
ProdList: 40066
Advantage: 58

Jilin Chinese Academy of Sciences-yanshen Technology

Tel: +undefined18143011203
Email: info@chemextension.com
Country: China
ProdList: 42056
Advantage: 58

Shanghai Acmec Biochemical Technology Co., Ltd.

Tel: +86-18621343501; +undefined18621343501
Email: product@acmec-e.com
Country: China
ProdList: 33338
Advantage: 58

Changzhou Watson Fine Chemical Co., Ltd

Tel: --
Fax: --
Email: sales@watsonchem.com
Country: China
ProdList: 172
Advantage: 67

Changzhou Hi-tech Chemicals Ltd

Tel: --
Fax: --
Email: mail@hitechem.com
Country: China
ProdList: 483
Advantage: 38

Beijing Goodturn Technology Co., Ltd.

Tel: --
Fax: --
Email: tech@goodturn.cn
Country: China
ProdList: 115
Advantage: 30

Shanghai Biochempartner Co., Ltd.

Tel: --
Fax: --
Country: China
ProdList: 757
Advantage: 50

Suzhou Rovathin Foreign Trade Co.,Ltd

Tel: --
Fax: --
Email: sales@rovathin.com
Country: China
ProdList: 4395
Advantage: 58

More

Less

View Lastest Price from Ethyl 2-amino-3-cyclobutylpropanoate manufacturers

Career Henan Chemical Co

Product: Ethyl 2-amino-3-cyclobutylpropanoate 394735-17-2
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1000kg
Release date: 2020-01-13

394735-17-2, Ethyl 2-amino-3-cyclobutylpropanoateRelated Search:

DL-Cyclobutylalanine Ethyl 2-amino-3-cyclobutylpropanoate

Ethyl 2-amino-3-cyclobutylpropanoate

2-AMino-3-cyclobutyl-propionic acid ethyl ester

Cyclobutanepropanoic acid, α-amino-, ethyl ester

2-amino-3-cyclobutylpropanoic acid ethyl ester

3-Cyclobutylalanine ethyl etser

Ethyl 3-cyclobutylalaninate

Cyclobutanepropanoicacid, a-amino-, ethyl ester

394735-17-2