ChemicalBook > CAS DataBase List > 4-bromo-2,5-difluorobenzoic acid
4-bromo-2,5-difluorobenzoic acid
- Product Name
- 4-bromo-2,5-difluorobenzoic acid
- CAS No.
- 28314-82-1
- Chemical Name
- 4-bromo-2,5-difluorobenzoic acid
- Synonyms
- 4-bromo-2,5-difluorobenzoic acid;2,5-Difluoro-4-broMobenzoic acid;Benzoic acid, 4-broMo-2,5-difluoro-;2-Propenoicacid,2-cyano-3-phenyl-,methylester,(5E)-;4-bromo-2,5-difluorobenzoic acid ISO 9001：2015 REACH
- CBNumber
- CB91559384
- Molecular Formula
- C7H3BrF2O2
- Formula Weight
- 237
- MOL File
- 28314-82-1.mol
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4-bromo-2,5-difluorobenzoic acid Property
- Boiling point:
- 285.0±40.0 °C(Predicted)
- Density
- 1.872±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 2.70±0.10(Predicted)
- form
- wooly powder
- color
- Creamy peach
- InChI
- InChI=1S/C7H3BrF2O2/c8-4-2-5(9)3(7(11)12)1-6(4)10/h1-2H,(H,11,12)
- InChIKey
- YWZSTHLOAZTDFJ-UHFFFAOYSA-N
- SMILES
- C(O)(=O)C1=CC(F)=C(Br)C=C1F
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Safety
- HS Code
- 2916399090
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
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N-Bromosuccinimide Price
TRC
- Product number
- B689698
- Product name
- 4-Bromo-2,5-difluorobenzoicacid
- Packaging
- 1g
- Price
- $75
- Updated
- 2021/12/16
Apolloscientific
- Product number
- PC501855
- Product name
- 4-Bromo-2,5-difluorobenzoicacid
- Packaging
- 1g
- Price
- $29
- Updated
- 2021/12/16
SynQuest Laboratories
- Product number
- 2621-B-50
- Product name
- 4-Bromo-2,5-difluorobenzoic acid
- Packaging
- 1g
- Price
- $32
- Updated
- 2021/12/16
Apolloscientific
- Product number
- PC501855
- Product name
- 4-Bromo-2,5-difluorobenzoicacid
- Packaging
- 5g
- Price
- $95
- Updated
- 2021/12/16
SynQuest Laboratories
- Product number
- 2621-B-50
- Product name
- 4-Bromo-2,5-difluorobenzoic acid
- Packaging
- 5G
- Price
- $104
- Updated
- 2021/12/16
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4-bromo-2,5-difluorobenzoic acid Chemical Properties,Usage,Production
Uses
4-Bromo-2,5-difluorobenzoic acid is a synthetic chemical compound that is widely used in scientific research. It is a versatile compound that can be used in many different laboratory experiments. It is also a fluorinated benzoic acid derivative and can be used as a reagent in a variety of organic and inorganic reactions.
Synthesis
Freshly titrated n-butyl lithium (27.0 ml, 1.39 M in hexanes) is added slowly (over about 30 minutes) to a -78°C solution of diethyl ether (90 ml) containing 1,4-dibromo-2,5-difluorobenzene (10.22 g, 0.038 mol). The resulting yellow solution is stirred at -78°C for 2 hours to give a yellow suspension. Several pellets (~10) of dry ice are added to the suspension, which is then allowed to warm slowly to room temperature as it degasses (approximately 40 minutes). The resulting suspension is acidified with a 1 M aqueous solution of hydrochloric acid (500 ml), and the product extracted with diethyl ether (5 x 200 ml). The combined organics are washed with water (4 x 100 ml) and filtered. The ether solution is concentrated to approximately 200 ml under reduced pressure, and the product extracted into a saturated aqueous solution of sodium bicarbonate (3 x 200 ml). The combined aqueous extracts are washed with methylene chloride (3 x 100 ml) and acidified with hydrochloric acid. The product is extracted with diethyl ether (3 x 200 ml), and the combined organic extracts washed with water (2 x 200 ml), dried over magnesium sulfate, and concentrated under reduced pressure to give 4-Bromo-2,5-difluorobenzoic acid as a pale yellow solid.
4-bromo-2,5-difluorobenzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-bromo-2,5-difluorobenzoic acid manufacturers
Hebei Weibang Biotechnology Co., Ltd
- Product
- 4-bromo-2,5-difluorobenzoic acid 28314-82-1
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-12-11
Career Henan Chemical Co
- Product
- 4-bromo-2,5-difluorobenzoic acid 28314-82-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2019-07-11