5-Hydroxy-1-methyl-1H-pyrazole-3-carboxylic acid
- Product Name
- 5-Hydroxy-1-methyl-1H-pyrazole-3-carboxylic acid
- CAS No.
- 58364-97-9
- Chemical Name
- 5-Hydroxy-1-methyl-1H-pyrazole-3-carboxylic acid
- Synonyms
- 5-Hydroxy-1-methyl-3-pyrazolecarboxylic acid;5-Hydroxy-1-methyl-1H-pyrazole-3-carboxylic acid;1H-Pyrazole-3-carboxylic acid, 5-hydroxy-1-methyl-;3-Carboxy-1-methyl-1H-pyrazol-5-ol, 3-Carboxy-5-hydroxy-1-methyl-1H-pyrazole
- CBNumber
- CB91563138
- Molecular Formula
- C5H6N2O3
- Formula Weight
- 142.11
- MOL File
- 58364-97-9.mol
5-Hydroxy-1-methyl-1H-pyrazole-3-carboxylic acid Property
- Melting point:
- 286 °C (decomp)
- Boiling point:
- 415.7±30.0 °C(Predicted)
- Density
- 1.56±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 9.39±0.28(Predicted)
- Appearance
- White to off-white Solid
Safety
- Hazard Codes
- Xi
- HS Code
- 2933199090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- H948918
- Product name
- 5-hydroxy-1-methyl-1H-pyrazole-3-carboxylicacid
- Packaging
- 500mg
- Price
- $350
- Updated
- 2021/12/16
- Product number
- OR12623
- Product name
- 5-Hydroxy-1-methyl-1H-pyrazole-3-carboxylicacid
- Packaging
- 250mg
- Price
- $56
- Updated
- 2021/12/16
- Product number
- 4H29-1-Z5
- Product name
- 5-Hydroxy-1-methyl-1H-pyrazole-3-carboxylic acid
- Packaging
- 250mg
- Price
- $61
- Updated
- 2021/12/16
- Product number
- OR12623
- Product name
- 5-Hydroxy-1-methyl-1H-pyrazole-3-carboxylicacid
- Packaging
- 1g
- Price
- $189
- Updated
- 2021/12/16
- Product number
- 4H29-1-Z5
- Product name
- 5-Hydroxy-1-methyl-1H-pyrazole-3-carboxylic acid
- Packaging
- 1g
- Price
- $208
- Updated
- 2021/12/16
5-Hydroxy-1-methyl-1H-pyrazole-3-carboxylic acid Chemical Properties,Usage,Production
Synthesis
51986-17-5
58364-97-9
The general procedure for the synthesis of 5-hydroxy-1-methyl-1H-pyrazole-3-carboxylic acid from ethyl 1-methyl-5-hydroxypyrazole-3-carboxylate is as follows: 1. ester hydrolysis: ethyl 1-methyl-5-hydroxypyrazole-3-carboxylate (20.00 g, 0.11 mol) was dissolved in water (100 mL), and sodium hydroxide pellets were added slowly with stirring to adjust the pH of the reaction solution to about 13. 2. After the reaction was completed (stirring at room temperature for 5 hours), the pH of the reaction solution was adjusted to 1 with 2N hydrochloric acid, at which time a precipitate was generated, and the precipitate was collected by filtration. 3. The resulting solid was mixed with acetone and stirred, filtered and dried to give the off-white solid product 5-hydroxy-1-methyl-1H-pyrazole-3-carboxylic acid (9.20 g, 59% yield). Mass spectrometry analysis showed (M-H)- peak of 141.
References
[1] Patent: WO2008/47071, 2008, A1. Location in patent: Page/Page column 21
5-Hydroxy-1-methyl-1H-pyrazole-3-carboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
5-Hydroxy-1-methyl-1H-pyrazole-3-carboxylic acid Suppliers
- Tel
- 001-857-928-2050 or 1-888-588-9418
- Fax
- 001-617-206-9595
- sales@chemreagents.com
- Country
- United States
- ProdList
- 10186
- Advantage
- 62
- Tel
- 86-0571-85151182
- Fax
- 86-0571-85151182
- Country
- China
- ProdList
- 5691
- Advantage
- 66
- Tel
- +86 (21) 6435-5022
- Country
- China
- ProdList
- 4267
- Advantage
- 65
- Tel
- 021-60343070
- Fax
- 021-35122006
- Country
- China
- ProdList
- 12740
- Advantage
- 55
- Tel
- 010-60400365-8001 15910885229
- Fax
- 010-60400361
- service@bellenchem.com
- Country
- China
- ProdList
- 4514
- Advantage
- 60
- Tel
- 0573-11111111-1111 18969316891
- Fax
- -
- richmol@163.com
- Country
- China
- ProdList
- 449
- Advantage
- 50
- Tel
- 18114022054; 18114022054
- Fax
- +86-25-58857385
- 3317707757@qq.com
- Country
- China
- ProdList
- 301
- Advantage
- 55
- Tel
- 0519-85528066 13775048983
- Fax
- 0519-85528066
- sales@hopschem.com
- Country
- China
- ProdList
- 31553
- Advantage
- 55
- Tel
- 15902830537
- zhanghao@happysyn.com
- Country
- China
- ProdList
- 3180
- Advantage
- 55
- Tel
- 571-89925085
- Fax
- 0086-571-89925065
- sales@amadischem.com
- Country
- China
- ProdList
- 131957
- Advantage
- 58