5-bromo-2-methylsulfanyl-3H-pyrimidin-4-one
- Product Name
- 5-bromo-2-methylsulfanyl-3H-pyrimidin-4-one
- CAS No.
- 81560-03-4
- Chemical Name
- 5-bromo-2-methylsulfanyl-3H-pyrimidin-4-one
- Synonyms
- pyrimidin-4(3H);5-Bromo-2-(methylthio);5-Bromo-2-(methylsulfanyl...;2-Methylsulfanyl-5-bromopyrimidin-4- one;5-bromo-2-(methylthio)-4(3H)-Pyrimidinone;5-Bromo-2-(methylthio)pyrimidin-4(3H)-one;5-Bromo-2-(methylthio)pyrimidin-4(1H)-one;5-bromo-2-methylsulfanyl-3H-pyrimidin-4-one;5-bromo-2-methylsulfanyl-1h-pyrimidin-6-one;4(3H)-Pyrimidinone, 5-bromo-2-(methylthio)-
- CBNumber
- CB91570170
- Molecular Formula
- C5H5BrN2OS
- Formula Weight
- 221.07
- MOL File
- 81560-03-4.mol
5-bromo-2-methylsulfanyl-3H-pyrimidin-4-one Property
- Melting point:
- 239 °C (decomp)(Solv: ethanol (64-17-5))
- Density
- 1.88±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 6.03±0.50(Predicted)
- Appearance
- White to off-white Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- B697735
- Product name
- 5-Bromo-2-methylsulfanylpyrimidin-4-ol
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- B697735
- Product name
- 5-Bromo-2-methylsulfanylpyrimidin-4-ol
- Packaging
- 500mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- B697735
- Product name
- 5-Bromo-2-methylsulfanylpyrimidin-4-ol
- Packaging
- 1g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 8H66-9-21
- Product name
- 5-Bromo-2-(methylsulfanyl)-3,4-dihydropyrimidin-4-one
- Purity
- 97.0%
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- J96414
- Product name
- 2-Methylsulfanyl-5-bromopyrimidin-4-one
- Packaging
- 10g
- Price
- $70
- Updated
- 2021/12/16
5-bromo-2-methylsulfanyl-3H-pyrimidin-4-one Chemical Properties,Usage,Production
Synthesis
5751-20-2
81560-03-4
Step 2, Preparation of 5-bromo-2-(methylthio)pyrimidin-4(3H)-one: 142 g of 2-methylthio-4-pyrimidinone was dissolved in 500 mL of dichloromethane, 190 g of N-bromosuccinimide (NBS) was added, and the reaction was heated and refluxed for 6 hours. After completion of the reaction, the reaction mixture was cooled to room temperature and filtered to remove insoluble material. The filter cake was washed with an appropriate amount of dichloromethane, and the organic phases were combined and dried with anhydrous sodium sulfate. The dried organic phase was recrystallized under ice bath conditions to give 190 g of light yellow solid product in 87% yield.
References
[1] Patent: CN107488175, 2017, A. Location in patent: Paragraph 0008; 0010
[2] Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1982, vol. 36, # 1 B, p. 15 - 18
[3] Patent: US6653316, 2003, B1. Location in patent: Page/Page column 117-118
[4] Patent: WO2005/99688, 2005, A2. Location in patent: Page/Page column 173
[5] Journal of the American Chemical Society, 1948, vol. 70, p. 1753,1755
5-bromo-2-methylsulfanyl-3H-pyrimidin-4-one Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-bromo-2-methylsulfanyl-3H-pyrimidin-4-one manufacturers
- Product
- 5-bromo-2-methylsulfanyl-3H-pyrimidin-4-one 81560-03-4
- Price
- US $150.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 500kg
- Release date
- 2024-11-13
- Product
- 5-bromo-2-methylsulfanyl-3H-pyrimidin-4-one 81560-03-4
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-12-02