Tripalmitin
- Product Name
- Tripalmitin
- CAS No.
- 555-44-2
- Chemical Name
- Tripalmitin
- Synonyms
- C16:0;barolub;PALMITIN;dynasan116;TRIPALMITIN;tri-palmiti;Tripalmotin;Dynasan 116;tripalmitate;palmitin,tri-
- CBNumber
- CB9163652
- Molecular Formula
- C51H98O6
- Formula Weight
- 807.32
- MOL File
- 555-44-2.mol
Tripalmitin Property
- Melting point:
- 66-68 °C
- Boiling point:
- bp 310-320°
- Density
- 0.8752 g/cm3 (70 ºC)
- refractive index
- nD80 1.43807
- storage temp.
- -20°C
- solubility
- Chloroform (Sparingly), Ethyl Acetate (Slightly), Hexanes (Very Slightly)
- form
- Fine Crystalline Powder
- color
- White to almost white
- biological source
- synthetic (organic)
- Merck
- 14,9736
- BRN
- 1811188
- LogP
- 21.615 (est)
- CAS DataBase Reference
- 555-44-2(CAS DataBase Reference)
- EPA Substance Registry System
- Tripalmitin (555-44-2)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- T5888
- Product name
- Glyceryl tripalmitate
- Purity
- ≥99%
- Packaging
- 1g
- Price
- $111.02
- Updated
- 2025/07/31
- Product number
- T5888
- Product name
- Glyceryl tripalmitate
- Purity
- ≥99%
- Packaging
- 5g
- Price
- $600
- Updated
- 2025/07/31
- Product number
- NIST1595A
- Product name
- Tripalmitin
- Purity
- NIST<SUP>®</SUP>SRM<SUP>®</SUP>595A
- Packaging
- 1 unit
- Price
- $2310
- Updated
- 2025/07/31
- Product number
- NIST1595
- Product name
- Tripalmitin
- Purity
- NIST? SRM? 1595
- Packaging
- 2G
- Price
- $1330
- Updated
- 2024/03/01
- Product number
- G0213
- Product name
- Tripalmitin
- Purity
- >85.0%(GC)
- Packaging
- 25g
- Price
- $118
- Updated
- 2025/07/31
Tripalmitin Chemical Properties,Usage,Production
Description
Tripalmitin, also known as Palmitin or 1,2,3-Tripalmitoyl glycerol, comes from the fatty acid palmitic acid and is a triacylglycerol that contains palmitic acid at the sn-1, sn-2, and sn-3 positions and has been found in palm oil. It inhibits glucose-stimulated insulin secretion and reduces viability of INS1 cells in a concentration-dependent manner. Myocardial levels of 1,2,3-tripalmitoyl glycerol are elevated by greater than 5-fold in a rat model of diabetes induced by streptozotocin . 1,2,3-Tripalmitoyl glycerol has been used to form the lipid matrices of etoposide-incorporated nanoparticles. Formulations containing 1,2,3-tripalmitoyl glycerol have been used in cosmetic products as thickening and skin-conditioning agents.
Chemical Properties
White, crystalline powder. Soluble in ether and chloroform; insoluble in water. Combustible.
Uses
Tripalmitin is a triglyceride derived from Palmitic Acid (P144500), a common fatty acid found in plants and animals. Tripalmitin is used in the preparation of solid lipid particles for oral delivery of drugs.
Uses
Soap, leather dressing.
Uses
Glyceryl tripalmitate has been used as a reference standard
- for the generation of calibration curve generation for the quantification of lipids from Azospirillum brasilense
- for the quantification of silk worm embryos and extraembryonic yolk lipids using thin layer chromatography
- for the quantification of triacylglycerol in Neochloris minuta microalgal cells
Definition
ChEBI: Tripalmitin is a triglyceride obtained by formal acylation of the three hydroxy groups of glycerol by palmitic (hexadecanoic) acid. It is functionally related to a hexadecanoic acid.
General Description
Biochem/physiol Actions
Glyceryl tripalmitate is a carrier molecule for effective drug delivery and is used solid lipid nanoparticle formulations.
Purification Methods
Crystallise it from acetone, diethyl ether or EtOH. It exists in an -form (m 56.0o), a ’-form (m 63.5o) and a -form (m 65.5o). [Beilstein 2 H 373, 2 I 167, 2 II 340, 2 III 971.]
References
[1] MIROSLAV LíSA Michal H. Triacylglycerols profiling in plant oils important in food industry, dietetics and cosmetics using high-performance liquid chromatography-atmospheric pressure chemical ionization mass spectrometry.[J]. Journal of Chromatography A, 2008, 1198-1199: 115-130. DOI: 10.1016/j.chroma.2008.05.037
[2] J H MOFFITT. Adverse physicochemical properties of tripalmitin in beta cells lead to morphological changes and lipotoxicity in vitro.[J]. Diabetologia, 2005: 1819-1829. DOI: 10.1007/s00125-005-1861-9
[3] LAKKIREDDY HARIVARDHAN REDDY. Etoposide-incorporated tripalmitin nanoparticles with different surface charge: formulation, characterization, radiolabeling, and biodistribution studies.[J]. AAPS Journal, 2004, 6 3: e23. DOI: 10.1208/aapsj060323
Tripalmitin Preparation Products And Raw materials
Raw materials
Preparation Products
Tripalmitin Suppliers
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View Lastest Price from Tripalmitin manufacturers
- Product
- TRIPALMITIN 555-44-2
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2018-12-25