DEAMINO-DICARBA-OXYTOCIN
- Product Name
- DEAMINO-DICARBA-OXYTOCIN
- CAS No.
- 14317-68-1
- Chemical Name
- DEAMINO-DICARBA-OXYTOCIN
- Synonyms
- [ASU 1,6] OT;[ASU 1,6] OXYTOCIN;DEAMINO-DICARBA-OXYTOCIN;oxytocin, 1,6-alpha-Asu-;TYR-ILE-GLN-ASN-ASU-PRO-LEU-GLY-NH2;CYCLO(TYR-ILE-GLN-ASN-ASU)-PRO-LEU-GLY-NH2;TYR-ILE-GLN-ASN-ASU-PRO-LEU-GLY-NH2: YIQN-ASU-PLG-NH2;Glycinamide, L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparaginyl-(2S)-2-amino-7-carboxyheptanoyl-L-prolyl-L-leucyl-, (5→1)-lactam
- CBNumber
- CB9176939
- Molecular Formula
- C45H69N11O12
- Formula Weight
- 956.1
- MOL File
- 14317-68-1.mol
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DEAMINO-DICARBA-OXYTOCIN Property
- Boiling point:
- 1475.3±65.0 °C(Predicted)
- Density
- 1.216±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- pka
- 9.91±0.15(Predicted)
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Safety
- Hazard Codes
- Xn
- Risk Statements
- 20
- Safety Statements
- 36/37/39-45
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N-Bromosuccinimide Price
American Custom Chemicals Corporation
- Product number
- PRK0000248
- Product name
- [ASU 16]OXYTOCIN
- Purity
- 95.00%
- Packaging
- 1MG
- Price
- $629.48
- Updated
- 2021/12/16
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DEAMINO-DICARBA-OXYTOCIN Chemical Properties,Usage,Production
Uses
[Asu1,6]-Oxytocin is an analog of oxytocin. [Asu1,6]-Oxytocin reverses insulin resistance and glucose intolerance prior to reduction of obesity. [Asu1,6]-Oxytocin has the potential for the research of obesity and diabetes[1].
in vivo
[Asu1,6]-Oxytocin (4 μg per injection; third-ventricle injection, twice injected for 7 days) improves glucose intolerance and lowers fasting blood insulin levels in mouse[1].
| Animal Model: | C57BL/6 mice[1] |
| Dosage: | 4 μg per injection |
| Administration: | Third-ventricle injection, twice injected for 7 days |
| Result: | Improved glucose intolerance and lowered fasting blood insulin levels, and both effects were independent of body weight. |
References
[1] Zhang H, et al. Treatment of obesity and diabetes using oxytocin or analogs in patients and mouse models. PLoS One. 2013 May 20;8(5):e61477. DOI:10.1371/journal.pone.0061477
DEAMINO-DICARBA-OXYTOCIN Preparation Products And Raw materials
Raw materials
Preparation Products
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