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N-CARBOXYETHYLRHODANINE

Product Name
N-CARBOXYETHYLRHODANINE
CAS No.
7025-19-6
Chemical Name
N-CARBOXYETHYLRHODANINE
Synonyms
AURORA 4785;AKOS BBS-00002147;IFLAB-BB F1902-0020;ART-CHEM-BB B023267;TIMTEC-BB SBB009645;OTAVA-BB BB0123270320;Rhodaninepropionicacid;rodanin-3-propionicacid;N-CARBOXYETHYLRHODANINE;Rodanin-3-propionic acid
CBNumber
CB9178559
Molecular Formula
C6H7NO3S2
Formula Weight
205.25
MOL File
7025-19-6.mol
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N-CARBOXYETHYLRHODANINE Property

Melting point:
158-160°C
Boiling point:
385.9±44.0 °C(Predicted)
Density 
1.61±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
form 
powder to crystal
pka
4.36±0.10(Predicted)
color 
Light yellow to Brown
CAS DataBase Reference
7025-19-6(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36/37/39
RTECS 
XJ6094060
HS Code 
2934.10.9000
HazardClass 
IRRITANT
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TCI Chemical
Product number
R0060
Product name
Rhodanine-3-propionic Acid
Purity
>98.0%(T)
Packaging
5g
Price
$143
Updated
2025/07/31
TCI Chemical
Product number
R0060
Product name
Rhodanine-3-propionic Acid
Purity
>98.0%(T)
Packaging
25g
Price
$458
Updated
2024/03/01
TRC
Product number
E588883
Product name
3-(4-Oxo-2-sulfanylidene-1,3-thiazolidin-3-yl)propanoicAcid
Packaging
100mg
Price
$60
Updated
2021/12/16
TRC
Product number
E588883
Product name
3-(4-Oxo-2-sulfanylidene-1,3-thiazolidin-3-yl)propanoicAcid
Packaging
500mg
Price
$90
Updated
2021/12/16
Ark Pharm
Product number
P000210227
Product name
3-(4-Oxo-2-thioxothiazolidin-3-yl)propanoic acid
Purity
97%
Packaging
250mg
Price
$6
Updated
2021/12/16
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N-CARBOXYETHYLRHODANINE Chemical Properties,Usage,Production

Synthesis

75-15-0

79-08-3

107-95-9

7025-19-6

Synthesis of 3-(4-oxo-2-thioxothiazolidin-3-yl)propionic acid (33): β-alanine 32 (3.4 g, 38.1 mmol) was dissolved in 17 mL of 22% potassium hydroxide solution, and the temperature of the reaction was controlled not to exceed 25 °C. Carbon disulfide (2.5 mL, 42 mmol) was added slowly and dropwise. The reaction mixture was stirred at room temperature. Subsequently, batchwise addition of bromoacetic acid (5.3 g, 38.1 mmol) was made over about 20 minutes, and the whole process was completed in about 3 hours. After addition, stirring was continued at room temperature for 3 hours, during which precipitation was observed. The pH of the reaction mixture was adjusted with concentrated hydrochloric acid to 3-4. After addition of sulfuric acid, the solution was stirred at room temperature overnight. The precipitate was collected by filtration and washed with water to give pure target compound 33 (3.52 g, 45% yield) as a yellow solid. Melting point 155-156 °C. 1H NMR (400 MHz, MeOD-d4) δ (ppm): 5.00 (brs, 1H), 4.22 (t, J = 7.5 Hz, 2H), 4.11 (s, 1H), 2.64 (t, J = 7.6 Hz, 2H). 13C NMR (100 MHz, MeOD-d4) δ (ppm): 202.58, 174.37, 172.87, 39.64, 35.08, 30.28. mass spectrum (ESI) m/z: 204.1 [M-H]+. Elemental analysis (C6H7NO3S2) Calculated values: C, 35.11; H, 3.44; N, 6.82. Measured values: C, 35.10; H, 3.48; N, 6.88.

References

[1] ChemMedChem, 2014, vol. 9, # 11, p. 2538 - 2547
[2] Patent: WO2011/39735, 2011, A2. Location in patent: Page/Page column 149-150
[3] ChemMedChem, 2014, vol. 9, # 11, p. 2538 - 2547

N-CARBOXYETHYLRHODANINE Preparation Products And Raw materials

Raw materials

Preparation Products

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N-CARBOXYETHYLRHODANINE Suppliers

Austria 1 Canada 2 CHINA 54 Germany 5 India 3 Japan 1 Russia 1 Ukraine 1 United Kingdom 7 United States 14 Global 89
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
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jkinfo@jkchemical.com
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China
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Alfa Aesar
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400-6106006
Fax
021-67582001/03/05
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saleschina@alfa-asia.com
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China
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TCI (Shanghai) Development Co., Ltd.
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021-67121386
Fax
021-67121385
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Sales-CN@TCIchemicals.com
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China
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24529
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Wuhan Chemwish Technology Co., Ltd
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86-027-67849912
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86-027-87531808
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sales@chemwish.com
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China
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Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
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+86-21-54098501
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+86-21-54096319
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sales@sinch.com.cn
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China
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Shandong Xiya Chemical Co., Ltd
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4009903999 13355009207
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0539-6365991
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3007715519@qq.com
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China
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TOKYO CHEMICAL INDUSTRY CO., LTD.
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03-36680489
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03-3668-0520
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Sales-JP@TCIchemicals.com
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9ding chemical ( Shanghai) Limited
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4009209199
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86-021-52271987
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sales@9dingchem.com
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China
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Shanghai Aladdin Bio-Chem Technology Co.,LTD
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400-6206333 13167063860
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021-50323701
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anhua.mao@aladdin-e.com
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China
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Zhengzhou HSH Science & Technology Co., Ltd.
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0371-55932928 18937192232
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0086-0371-55932928
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1282296214@qq.com
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7025-19-6, N-CARBOXYETHYLRHODANINERelated Search:

Beclomethasone dipropionate Rhodanine N-CARBOXYETHYLRHODANINE 3-[(5Z)-4-OXO-5-(2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)-2-THIOXO-1,3-THIAZOLIDIN-3-YL]PROPANOIC ACID 3-[(5Z)-5-(1-METHYL-2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-3-YL]PROPANOIC ACID 3-[(5Z)-5-BENZYLIDENE-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-3-YL]PROPANOIC ACID AURORA 5304 2-[(5Z)-5-(4-CHLOROBENZYLIDENE)-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-3-YL]SUCCINIC ACID 3-[5-(3,4-DIMETHOXY-BENZYLIDENE)-4-OXO-2-THIOXO-THIAZOLIDIN-3-YL]-PROPIONIC ACID SALOR-INT L334480-1EA 3-[5-(4-BROMO-BENZYLIDENE)-4-OXO-2-THIOXO-THIAZOLIDIN-3-YL]-PROPIONIC ACID 3-[5-(4-FLUORO-BENZYLIDENE)-4-OXO-2-THIOXO-THIAZOLIDIN-3-YL]-PROPIONIC ACID 3-[5-(3-BROMO-BENZYLIDENE)-4-OXO-2-THIOXO-THIAZOLIDIN-3-YL]-PROPIONIC ACID 3-[5-(4-METHOXY-BENZYLIDENE)-4-OXO-2-THIOXO-THIAZOLIDIN-3-YL]-PROPIONIC ACID AKOS BBS-00002177 3-[5-(4-CHLORO-BENZYLIDENE)-4-OXO-2-THIOXO-THIAZOLIDIN-3-YL]-PROPIONIC ACID 3-[(5Z)-5-(5-BROMO-2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-3-YL]PROPANOIC ACID SALOR-INT L333727-1EA

  • 3-Thiazolidinepropanoic acid, 4-oxo-2-thioxo-
  • 3-Thiazolidinepropionic acid, 4-oxo-2-thioxo-
  • 4-oxo-2-thioxo-3-thiazolidinepropionicaci
  • Rodanin-3-propionic acid
  • rodanin-3-propionicacid
  • AKOS BBS-00002147
  • 3-(4-OXO-2-THIOXO-1,3-THIAZOLIDIN-3-YL)PROPANOIC ACID
  • 3-(4-OXO-2-THIOXO-THIAZOLIDIN-3-YL)-PROPIONIC ACID
  • 4-OXO-2-THIOXO-3-THIAZOLIDINEPROPIONIC ACID
  • IFLAB-BB F1902-0020
  • AURORA 4785
  • ART-CHEM-BB B023267
  • 3-(2-CARBOXYETHYL)-2-THIOXOTHIAZOLIDIN-4-ONE
  • 3-(2-Carboxyethyl)rhodanine
  • 4-Oxo-2-thioxo-3-thiazolidinepropanoic acid
  • N-CARBOXYETHYLRHODANINE
  • OTAVA-BB BB0123270320
  • N-(2-CARBOXYETHYL)RHODANINE
  • RHODANINE-3-PROPIONIC ACID
  • TIMTEC-BB SBB009645
  • Rhodaninepropionicacid
  • 4-oxo-2-thioxothiazolidine-3-propionic acid
  • 3-(4-Oxo-2-thioxo-3-thiazolidinyl)propionic acid, 95%
  • 3-(4-Oxo-2-thioxothiazolidin-3-yl)propanoic acid
  • Rhodanine-3-propionicAcid&gt
  • 3-(4-Oxo-2-sulfanylidene-1,3-thiazolidin-3-yl)propanoic Acid
  • 3-RHODANINEPROPIONIC ACID
  • Rhodanine-3-propionic acid (RPA)
  • 7025-19-6
  • C6H7NO3S2