ChemicalBook > CAS DataBase List > Angeli’s Salt

Angeli’s Salt

Product Name
Angeli’s Salt
CAS No.
13826-64-7
Chemical Name
Angeli’s Salt
Synonyms
AS;Angeli Salt;ANGELI'S SALT;Angeli’s Salt;Sodium hyponitrate;Sodium oxyhyponitrite;SODIUM TRIOXODINITRATE;SODIUM ALPHA-OXYHYPONITRITE;CUVSFFFYSKZMEE-UHFFFAOYSA-N;HYPONITRIC ACID DISODIUM SALT
CBNumber
CB9219704
Molecular Formula
N2Na3O3+
Formula Weight
144.98
MOL File
13826-64-7.mol
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Angeli’s Salt Property

Density 
2.26 (monohydrate)
storage temp. 
Store at -20°C
solubility 
H20: 50 mg/ml; PBS (pH 7.2): 50 mg/ml
form 
A crystalline solid
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
176695
Product name
Angeli’s Salt - CAS 13826-64-7 - Calbiochem
Packaging
10mg
Price
$125
Updated
2024/03/01
Cayman Chemical
Product number
82230
Product name
Angeli’s Salt
Purity
≥99%
Packaging
5mg
Price
$30
Updated
2024/03/01
Cayman Chemical
Product number
82230
Product name
Angeli’s Salt
Purity
≥99%
Packaging
10mg
Price
$56
Updated
2024/03/01
Cayman Chemical
Product number
82230
Product name
Angeli’s Salt
Purity
≥99%
Packaging
50mg
Price
$225
Updated
2024/03/01
Cayman Chemical
Product number
82230
Product name
Angeli’s Salt
Purity
≥99%
Packaging
100mg
Price
$392
Updated
2024/03/01
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Angeli’s Salt Chemical Properties,Usage,Production

Description

The chemical feat that perhaps best illustrates Angeli's intuitive talent was the discovery more than a century ago of the sodium salt of nitroxylaminic acid, also called Angeli's Salt (Na2N2O3). Na2[ON=NO2] is regarded as a classic nitroxyl(N=O-) donor, but under certain conditions evolution of NO is also observed. Angelo Angeli found that'salts of nitroxylaminic acid are readily resolved into the corresponding nitrites and the unsaturated nitroxyl residue. Angeli suggested their use as possible in vitro and in vivo sources of HNO,but physiological properties of this molecule didn't attract very much attention until the end of the 20th century.
Angeli's salt can be conveniently synthesized by treating hydroxylamine hydrochloride with excess sodium hydroxide,yielding hydroxylamine,which is further treated with butyl nitrate to produce the salt as a white solid.

Uses

HNO/NO- donor in biochemical model studies.

Uses

Sodium Oxyhyponitrite is used in the treatment for hemolysis.

General Description

A nitroxyl anion (NO) donor that spontaneously dissociates in a pH dependent first order process to liberate 0.54 moles of NO per mole of the parent compound. Half-life (t?) in 100 mM phosphate buffer, pH 7.4 is 2.3 minutes at 37°C. Decomposition is nearly instantaneous at pH 5.0.

Biochem/physiol Actions

Primary TargetNitroxyl anion (NO-) donor

Angeli’s Salt Preparation Products And Raw materials

Raw materials

Preparation Products

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13826-64-7, Angeli’s SaltRelated Search:


  • ANGELI'S SALT
  • AS
  • HYPONITRIC ACID DISODIUM SALT
  • DISODIUM DIAZEN-1-IUM-1,2,2-TRIOLATE
  • SODIUM TRIOXODINITRATE
  • SODIUM ALPHA-OXYHYPONITRITE
  • Sodium oxyhyponitrite
  • Sodium N-nitrohydroxylaminate
  • Sodium hyponitrate
  • CUVSFFFYSKZMEE-UHFFFAOYSA-N
  • Angeli Salt
  • Angeli’s Salt
  • 13826-64-7
  • N2Na3O3
  • Na2N2O3