3-Methyl-5-phenyl-7-chloro-1H-1,4-benzodiazepine-2(3H)-one Property

Melting point:

217-219 °C(Solv: ethyl acetate (141-78-6))

Boiling point:

453.7±45.0 °C(Predicted)

Density 

1.29±0.1 g/cm3(Predicted)

solubility 

DMF: 2 mg/mL; DMSO: 1 mg/mL; Ethanol: Slightly soluble; PBS (pH 7.2): 0.25 mg/mL

form 

A solid

pka

11.76±0.70(Predicted)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H332Harmful if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P322Specific measures (see …on this label).

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

3-Methyl-5-phenyl-7-chloro-1H-1,4-benzodiazepine-2(3H)-one Chemical Properties,Usage,Production

Description

3-Methylnordiazepam is an analytical reference standard categorized as a benzodiazepine.¹ 3-Methylnordiazepam has anticonvulsant activity in mice. This product is intended for research and forensic applications.

References

1. Klopman, G., and Contreras, R. Use of artificial intelligence in structure-activity correlations of anticonvulsant drugs Mol. Pharmacol. 27(1),86-93(1985).