Description Sources
ChemicalBook > CAS DataBase List > 4-CHLORO-2-NITROPHENOL

4-CHLORO-2-NITROPHENOL

Description Sources
Product Name
4-CHLORO-2-NITROPHENOL
CAS No.
89-64-5
Chemical Name
4-CHLORO-2-NITROPHENOL
Synonyms
AKOS BBS-00004667;4-CHLORO-2-NITROPHEN;o-nitro-p-chorophenol;4-chloro-2-nitro-pheno;O-NITRO-P-CHLOROPHENOL;2-NITRO-4-CHLOROPHENOL;4-CHLORO-2-NITROPHENOL;Phenol,4-chloro-2-nitro-;4-chloro-2-nitrophenolate;4-Chloro-2-nitrophenol,98%
CBNumber
CB9226357
Molecular Formula
C6H4ClNO3
Formula Weight
173.55
MOL File
89-64-5.mol
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4-CHLORO-2-NITROPHENOL Property

Melting point:
85-87 °C(lit.)
Boiling point:
242.5±20.0 °C(Predicted)
Density 
1.4914 (rough estimate)
refractive index 
1.5810 (estimate)
solubility 
dioxane: soluble0.5g/5mL, clear, faintly yellow to yellow
pka
pK1: 6.48 (25°C)
form 
powder to crystal
color 
Light yellow to Yellow to Orange
BRN 
2048031
CAS DataBase Reference
89-64-5(CAS DataBase Reference)
EPA Substance Registry System
4-Chloro-2-nitrophenol (89-64-5)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-20/21/22
Safety Statements 
26-36-36/37/39
RIDADR 
2811
WGK Germany 
3
TSCA 
Yes
HazardClass 
6.1
PackingGroup 
III
HS Code 
29089990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
25580
Product name
4-Chloro-2-nitrophenol
Purity
≥97.0%
Packaging
250g
Price
$203
Updated
2024/03/01
TCI Chemical
Product number
C0228
Product name
4-Chloro-2-nitrophenol
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$36
Updated
2023/06/20
TCI Chemical
Product number
C0228
Product name
4-Chloro-2-nitrophenol
Purity
>98.0%(GC)(T)
Packaging
500g
Price
$299
Updated
2023/01/07
Alfa Aesar
Product number
A18150
Product name
4-Chloro-2-nitrophenol, 98%, contains up to ca 10% water
Packaging
25g
Price
$31.8
Updated
2023/06/20
Alfa Aesar
Product number
A18150
Product name
4-Chloro-2-nitrophenol, 98%, contains up to ca 10% water
Packaging
100g
Price
$69.1
Updated
2021/12/16
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4-CHLORO-2-NITROPHENOL Chemical Properties,Usage,Production

Description

4-Chloro-2-nitrophenol, is a kind of chloronitrophenols (CNPs), being widely used in the synthesis of dyes, drugs and pesticides. Furthermore, it can be used to produce 2-Amino-4-chloro-phenol.It has become a major group of environmental pollutants. 4-Chloro-2-nitrophenol has been detected in various industrial effluents. Therefore, it has also been used as a model compound for evaluation of biodegradation strategy using microbes.

Sources

https://microbialcellfactories.biomedcentral.com/articles/10.1186/1475-2859-11-150
https://www.sciencedirect.com/science/article/pii/S0304389407009570
https://www.lookchem.com/4-Chloro-2-nitrophenol/

Chemical Properties

yellow powder

Uses

Reduction of 4-Chloro-2-nitrophenol gives 2-amino-4- chlorophenol [95-85-2], and chlorination yields 2,4-dichloro-6-nitrophenol [609-89-2], which is reduced to 2-amino-4,6-dichlorophenol [527-62-8]. These substituted aminophenols are members of a large class of diazo components used for hydroxyazo dyes, which are important for wool and polyamide when converted to their chromium complexes. For the amine derived from the methyl ether of 4-Chloro-2-nitrophenol, 4- chloro-o-anisidine [93-50-5], the preferred route is methoxylation of 2,5-dichloronitrobenzene followed by reduction. 2-amino-4-chlorophenol reacts with phosgene to give 5- chlorobenzoxolinone which nitrates to the 6-nitro compound; the latter undergoes alkaline hydrolysis to 2-amino-4- chloro-5-nitrophenol.

Production Methods

2,5-Dichloronitrobenzene is hydrolyzed with 8 % aqueous sodium hydroxide at 120 – 130 ℃ under pressure.

4-CHLORO-2-NITROPHENOL Preparation Products And Raw materials

Raw materials

Preparation Products

Chlorzoxazone 2-Amino-4-chlorophenol
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4-CHLORO-2-NITROPHENOL Suppliers

Global 0

89-64-5, 4-CHLORO-2-NITROPHENOLRelated Search:

2,4-Dichloro-6-nitrophenol 4-CHLORO-2,6-DINITROPHENOL 4-Chloro-2-nitroanisole 4-CHLORO-2-NITROPHENOL 2,4-Dichloro-3-ethyl-6-nitrophenol Benzoic acid,5-chloro-2-hydroxy-3-nitro- 2-amino-4-chloro-6-nitrophenol monohydrochloride ,2-Amino-4-chloro-6-nitrophenol hydrochloride 4-CHLORO-6-NITRO-M-CRESOL 3-CHLORO-2,6-DIMETHOXY-5-NITROBENZOIC ACID 2-AMINO-4-CHLORO-6-NITROPHENOL 4-Chloro-1-(4-chlorophenoxy)-2-nitrobenzene 2,4-Dichloro-3-methyl-6-nitrophenol 3,4,6-TRICHLORO-2-NITROPHENOL 5-chloro-2-nitrophenol 2-(4-CHLOROPHENOXY)NICOTINIC ACID 2,6-Dichloro-4-nitrophenol 4-CHLORO-3-NITROPHENOL,4-Chloro-3-Nitrophenol98%,4-CHLORO-3-NITROPHENOL 98% 2,4-Dichloro-5-nitrophenol

  • O-NITRO-P-CHLOROPHENOL
  • 4-chloro-2-nitro-pheno
  • AKOS BBS-00004667
  • 4-CHLORO-2-NITROPHENOL
  • 1-CHLORO-4-HYDROXY-3-NITROBENZENE
  • 2-NITRO-4-CHLOROPHENOL
  • o-nitro-p-chorophenol
  • 4-Chloro-2-nitrophenol,98%,containsuptoca10%water
  • 4-CHLORO-2-NITROPHENOL , CONTAINS UP TO CA 10% WATER
  • 4-Chloro-2-nitrophenol,98%
  • 4-CHLORO-2-NITROPHEN
  • 4-Chloro-2-nitrophenol >=97.0%
  • 2-Nitro-4-chlorophenol,p-Chloro-o-nitrophenol
  • 4-chloro-2-nitrophenolate
  • 4-Chloro-2-nitrophenol &gt
  • Phenol,4-chloro-2-nitro-
  • 4-Chloro-2-nitrophenol, ≥97%
  • 89-64-5
  • ClNO2C6H3OH
  • C6H3ClNO3
  • Organic Building Blocks
  • Phenols
  • Oxygen Compounds
  • Building Blocks
  • Dyestuff Intermediates
  • Organic Building Blocks
  • Oxygen Compounds
  • Phenols
  • Aromatic Phenols
  • Phenoles and thiophenoles
  • Intermediates of Dyes and Pigments