Description Sources
ChemicalBook > CAS DataBase List > 4-CHLORO-2-NITROPHENOL

4-CHLORO-2-NITROPHENOL

Description Sources
Product Name
4-CHLORO-2-NITROPHENOL
CAS No.
89-64-5
Chemical Name
4-CHLORO-2-NITROPHENOL
Synonyms
AKOS BBS-00004667;4-CHLORO-2-NITROPHEN;o-nitro-p-chorophenol;4-chloro-2-nitro-pheno;O-NITRO-P-CHLOROPHENOL;2-NITRO-4-CHLOROPHENOL;4-CHLORO-2-NITROPHENOL;Phenol,4-chloro-2-nitro-;4-chloro-2-nitrophenolate;4-Chloro-2-nitrophenol,98%
CBNumber
CB9226357
Molecular Formula
C6H4ClNO3
Formula Weight
173.55
MOL File
89-64-5.mol
More
Less

4-CHLORO-2-NITROPHENOL Property

Melting point:
85-87 °C(lit.)
Boiling point:
242.5±20.0 °C(Predicted)
Density 
1.4914 (rough estimate)
refractive index 
1.5810 (estimate)
solubility 
dioxane: soluble0.5g/5mL, clear, faintly yellow to yellow
form 
powder to crystal
pka
pK1: 6.48 (25°C)
color 
Light yellow to Yellow to Orange
BRN 
2048031
Henry's Law Constant
7.8×10-1 mol/(m3Pa) at 25℃, Duchowicz et al. (2020)
CAS DataBase Reference
89-64-5(CAS DataBase Reference)
EPA Substance Registry System
4-Chloro-2-nitrophenol (89-64-5)
More
Less

Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-20/21/22
Safety Statements 
26-36-36/37/39
RIDADR 
2811
WGK Germany 
3
TSCA 
TSCA listed
HazardClass 
6.1
PackingGroup 
III
HS Code 
29089990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
25580
Product name
4-Chloro-2-nitrophenol
Purity
≥97.0%
Packaging
250g
Price
$203
Updated
2024/03/01
TCI Chemical
Product number
C0228
Product name
4-Chloro-2-nitrophenol
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$27
Updated
2026/03/19
TCI Chemical
Product number
C0228
Product name
4-Chloro-2-nitrophenol
Purity
>98.0%(GC)(T)
Packaging
500g
Price
$299
Updated
2023/01/07
TRC
Product number
C384768
Product name
4-Chloro-2-nitrophenol
Packaging
40g
Price
$65
Updated
2021/12/16
AK Scientific
Product number
L684
Product name
4-Chloro-2-nitrophenol
Packaging
25g
Price
$77
Updated
2021/12/16
More
Less

4-CHLORO-2-NITROPHENOL Chemical Properties,Usage,Production

Description

4-Chloro-2-nitrophenol, is a kind of chloronitrophenols (CNPs), being widely used in the synthesis of dyes, drugs and pesticides. Furthermore, it can be used to produce 2-Amino-4-chloro-phenol.It has become a major group of environmental pollutants. 4-Chloro-2-nitrophenol has been detected in various industrial effluents. Therefore, it has also been used as a model compound for evaluation of biodegradation strategy using microbes.

Sources

https://microbialcellfactories.biomedcentral.com/articles/10.1186/1475-2859-11-150
https://www.sciencedirect.com/science/article/pii/S0304389407009570
https://www.lookchem.com/4-Chloro-2-nitrophenol/

Chemical Properties

yellow powder

Uses

Reduction of 4-Chloro-2-nitrophenol gives 2-amino-4- chlorophenol [95-85-2], and chlorination yields 2,4-dichloro-6-nitrophenol [609-89-2], which is reduced to 2-amino-4,6-dichlorophenol [527-62-8]. These substituted aminophenols are members of a large class of diazo components used for hydroxyazo dyes, which are important for wool and polyamide when converted to their chromium complexes. For the amine derived from the methyl ether of 4-Chloro-2-nitrophenol, 4- chloro-o-anisidine [93-50-5], the preferred route is methoxylation of 2,5-dichloronitrobenzene followed by reduction. 2-amino-4-chlorophenol reacts with phosgene to give 5- chlorobenzoxolinone which nitrates to the 6-nitro compound; the latter undergoes alkaline hydrolysis to 2-amino-4- chloro-5-nitrophenol.

Production Methods

2,5-Dichloronitrobenzene is hydrolyzed with 8 % aqueous sodium hydroxide at 120 – 130 ℃ under pressure.

4-CHLORO-2-NITROPHENOL Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

4-CHLORO-2-NITROPHENOL Suppliers

Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
86249
Advantage
60
CD Chemical Group Limited
Tel
+8615986615575
Fax
0086-13651442114
Email
info@codchem.com
Country
China
ProdList
17259
Advantage
58
Shanghai Yanze Chemical Co., Ltd.
Tel
13773155751 15345144255
Email
260924549@qq.com
Country
China
ProdList
9991
Advantage
58
Huaian Jiamu Biotechnology Co., Ltd.
Tel
0517-83187139 18205232085
Email
cai@jiamu-bio.com
Country
China
ProdList
2965
Advantage
58
NINGBO JL NEW MATERIAL CO.,LTD
Tel
0574 88552218 18969899212
Email
sales@chematerials.cn
Country
China
ProdList
1342
Advantage
58
Shanghai Maclean Biochemical Technology Co., LTD
Tel
021-50706066 15221275939
Email
shenlinxing@macklin.cn
Country
China
ProdList
29680
Advantage
58
Shanghai Aladdin Biochemical Technology Co.,Ltd.
Tel
400-6206333 13167063860
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
49573
Advantage
58
Shanghai Baoyang Baoxin Biotechnology Co., LTD
Tel
021-56698539 19921169802
Email
bxsw_sh@163.com
Country
China
ProdList
3917
Advantage
58
Beijing Putian Tongchuang Biotechnology Co., Ltd.
Tel
18201332838
Email
3032079623@qq.com
Country
China
ProdList
6695
Advantage
58
Merck KGaA
Tel
21-20338288
Email
ordercn@merckgroup.com
Country
China
ProdList
6038
Advantage
58

89-64-5, 4-CHLORO-2-NITROPHENOLRelated Search:


  • O-NITRO-P-CHLOROPHENOL
  • 4-chloro-2-nitro-pheno
  • AKOS BBS-00004667
  • 4-CHLORO-2-NITROPHENOL
  • 1-CHLORO-4-HYDROXY-3-NITROBENZENE
  • 2-NITRO-4-CHLOROPHENOL
  • o-nitro-p-chorophenol
  • 4-Chloro-2-nitrophenol,98%,containsuptoca10%water
  • 4-CHLORO-2-NITROPHENOL , CONTAINS UP TO CA 10% WATER
  • 4-Chloro-2-nitrophenol,98%
  • 4-CHLORO-2-NITROPHEN
  • 4-Chloro-2-nitrophenol >=97.0%
  • 2-Nitro-4-chlorophenol,p-Chloro-o-nitrophenol
  • 4-chloro-2-nitrophenolate
  • 4-Chloro-2-nitrophenol &gt
  • Phenol,4-chloro-2-nitro-
  • 4-Chloro-2-nitrophenol, ≥97%
  • 89-64-5
  • ClNO2C6H3OH
  • C6H3ClNO3
  • Organic Building Blocks
  • Phenols
  • Oxygen Compounds
  • Building Blocks
  • Dyestuff Intermediates
  • Organic Building Blocks
  • Oxygen Compounds
  • Phenols
  • Aromatic Phenols
  • Phenoles and thiophenoles
  • Intermediates of Dyes and Pigments