4,4'-SULFONYLBIS(2-METHYLPHENOL)
- Product Name
- 4,4'-SULFONYLBIS(2-METHYLPHENOL)
- CAS No.
- 16346-97-7
- Chemical Name
- 4,4'-SULFONYLBIS(2-METHYLPHENOL)
- Synonyms
- Topoisomerase IIα-IN-9;4,4'-Sulfonylbis(2-methylphenol);4,4'-Sulfonylbis(2-methylphenol);Phenol, 4,4'-sulfonylbis[2-methyl-;3,3'-DIMETHYL-4,4'-DIHYDROXYDIPHENYL SULFONE;4,4'-Dihydroxy-3,3'-dimethyl[sulfonylbisbenzene]
- CBNumber
- CB9228391
- Molecular Formula
- C14H14O4S
- Formula Weight
- 278.32
- MOL File
- 16346-97-7.mol
4,4'-SULFONYLBIS(2-METHYLPHENOL) Property
- Melting point:
- 273-276 °C(lit.)
- Boiling point:
- 518.8±50.0 °C(Predicted)
- Density
- 1.343±0.06 g/cm3(Predicted)
- solubility
- DMSO (Slightly), Methanol (Slightly, Heated)
- form
- Solid
- pka
- 7.25±0.20(Predicted)
- color
- Pale Orange to Pale Red
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 476269
- Product name
- 4,4′-Sulfonylbis(2-methylphenol)
- Purity
- 97%
- Packaging
- 50g
- Price
- $69.72
- Updated
- 2025/07/31
- Product number
- H947743
- Product name
- 4-(4-Hydroxy-3-methylbenzenesulfonyl)-2-methylphenol
- Packaging
- 50mg
- Price
- $70
- Updated
- 2021/12/16
- Product number
- H947743
- Product name
- 4-(4-Hydroxy-3-methylbenzenesulfonyl)-2-methylphenol
- Packaging
- 25mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- ING0001970
- Product name
- 4,4'-SULFONYLBIS(2-METHYLPHENOL)
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $154.35
- Updated
- 2021/12/16
- Product number
- 6330BA
- Product name
- 4,4'-Sulfonylbis(2-methylphenol)
- Packaging
- 5g
- Price
- $407
- Updated
- 2021/12/16
4,4'-SULFONYLBIS(2-METHYLPHENOL) Chemical Properties,Usage,Production
Uses
Topoisomerase IIα-IN-9 (NSC85582) is a bisphenol compound that has a moderate inhibitory effect on DNA topoisomerase Topoisomerase II (IC50: 571 μM). Topoisomerase IIα-IN-9 also exhibits a certain cell growth inhibitory effect, with IC50s of 117 μM and 218 μM for K562 and CHO, respectively[1].
References
[1] A Three-Dimensional Quantitative Structure-Activity Analysis of a New Class of Bisphenol Topoisomerase II Inhibitors
4,4'-SULFONYLBIS(2-METHYLPHENOL) Preparation Products And Raw materials
Raw materials
Preparation Products
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