ChemicalBook > CAS DataBase List > 4,4'-SULFONYLBIS(2-METHYLPHENOL)

4,4'-SULFONYLBIS(2-METHYLPHENOL)

Product Name
4,4'-SULFONYLBIS(2-METHYLPHENOL)
CAS No.
16346-97-7
Chemical Name
4,4'-SULFONYLBIS(2-METHYLPHENOL)
Synonyms
Topoisomerase IIα-IN-9;4,4'-Sulfonylbis(2-methylphenol);4,4'-Sulfonylbis(2-methylphenol);Phenol, 4,4'-sulfonylbis[2-methyl-;3,3'-DIMETHYL-4,4'-DIHYDROXYDIPHENYL SULFONE;4,4'-Dihydroxy-3,3'-dimethyl[sulfonylbisbenzene]
CBNumber
CB9228391
Molecular Formula
C14H14O4S
Formula Weight
278.32
MOL File
16346-97-7.mol
More
Less

4,4'-SULFONYLBIS(2-METHYLPHENOL) Property

Melting point:
273-276 °C(lit.)
Boiling point:
518.8±50.0 °C(Predicted)
Density 
1.343±0.06 g/cm3(Predicted)
solubility 
DMSO (Slightly), Methanol (Slightly, Heated)
form 
Solid
pka
7.25±0.20(Predicted)
color 
Pale Orange to Pale Red
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
476269
Product name
4,4′-Sulfonylbis(2-methylphenol)
Purity
97%
Packaging
50g
Price
$69.72
Updated
2025/07/31
TRC
Product number
H947743
Product name
4-(4-Hydroxy-3-methylbenzenesulfonyl)-2-methylphenol
Packaging
50mg
Price
$70
Updated
2021/12/16
TRC
Product number
H947743
Product name
4-(4-Hydroxy-3-methylbenzenesulfonyl)-2-methylphenol
Packaging
25mg
Price
$50
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
ING0001970
Product name
4,4'-SULFONYLBIS(2-METHYLPHENOL)
Purity
95.00%
Packaging
1G
Price
$154.35
Updated
2021/12/16
AK Scientific
Product number
6330BA
Product name
4,4'-Sulfonylbis(2-methylphenol)
Packaging
5g
Price
$407
Updated
2021/12/16
More
Less

4,4'-SULFONYLBIS(2-METHYLPHENOL) Chemical Properties,Usage,Production

Uses

Topoisomerase IIα-IN-9 (NSC85582) is a bisphenol compound that has a moderate inhibitory effect on DNA topoisomerase Topoisomerase II (IC50: 571 μM). Topoisomerase IIα-IN-9 also exhibits a certain cell growth inhibitory effect, with IC50s of 117 μM and 218 μM for K562 and CHO, respectively[1].

References

[1] A Three-Dimensional Quantitative Structure-Activity Analysis of a New Class of Bisphenol Topoisomerase II Inhibitors

4,4'-SULFONYLBIS(2-METHYLPHENOL) Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

4,4'-SULFONYLBIS(2-METHYLPHENOL) Suppliers

SynAsst Chemical.
Tel
021-60343070
Fax
021-35122006
Country
China
ProdList
12740
Advantage
55
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51395
Advantage
80
Alfa Chemistry
Tel
1-516-6625404
Fax
1-516-927-0118
Email
support@alfa-chemistry.com
Country
United States
ProdList
9171
Advantage
60
Aikon International Limited
Tel
025-58851090 15955137747
Fax
(6)02557626880
Email
sales01@aikonchem.com
Country
China
ProdList
15949
Advantage
58
Alfa Chemistry
Tel
+1-5166625404;
Fax
1-516-927-0118
Email
Info@alfa-chemistry.com
Country
United States
ProdList
20405
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing@energy-chemical.com
Country
China
ProdList
44918
Advantage
58
LGC Science (Shanghai) Ltd.
Tel
17717235263
Email
cindy.yang@lgcgroup.com
Country
China
ProdList
18003
Advantage
58
Shanghai Haohong Scientific Co., Ltd.
Tel
400-8210725 4008210725
Email
malulu@leyan.com
Country
China
ProdList
39845
Advantage
58
Honghanyanxin Pharm
Tel
0551-62626652 19334025048
Email
sales-honghanyanxin@aliyun.com
Country
China
ProdList
1164
Advantage
58
Baoji Didu Pharmaceutical and Chemical Co., Ltd
Tel
029-029-81148929 17791530722
Email
1049@dideu.com
Country
China
ProdList
10011
Advantage
58