5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-ylamine

Product Name: 5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-ylamine
CAS No.: 92050-16-3
Chemical Name: 5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-ylamine
Synonyms: Tamibarotene Impurity 1;5,5,8,8-TetraMethyl-6,7-dihydronaphthalen-2-aMine;5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-napthylamine;5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthylamine;5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-amine;2-Amino-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalene;2-Naphthalenamine,5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-;5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-ylamine;5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-ylamine，98% min;5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-ylamine ISO 9001：2015 REACH
CBNumber: CB92469914
Molecular Formula: C14H21N
Formula Weight: 203.32
MOL File: 92050-16-3.mol

More

Less

5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-ylamine Property

Melting point:: 63-65℃
Boiling point:: 310.2±31.0 °C(Predicted)
Density: 0.944
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
pka: 5.16±0.60(Predicted)
Appearance: Off-white to light brown Solid
InChI: InChI=1S/C14H21N/c1-13(2)7-8-14(3,4)12-9-10(15)5-6-11(12)13/h5-6,9H,7-8,15H2,1-4H3
InChIKey: AMDKYPNODLTUMY-UHFFFAOYSA-N
SMILES: C1=C2C(C(C)(C)CCC2(C)C)=CC=C1N

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

TRC

Product number: T890340
Product name: 5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-amine
Packaging: 50mg
Price: $90
Updated: 2021/12/16

AK Scientific

Product number: X0040
Product name: 5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthylamine
Packaging: 1g
Price: $401
Updated: 2021/12/16

Crysdot

Product number: CD12007133
Product name: 5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-amine
Purity: 97%
Packaging: 5g
Price: $420
Updated: 2021/12/16

Chemenu

Product number: CM133424
Product name: 5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-amine
Purity: 95+%
Packaging: 5g
Price: $842
Updated: 2021/12/16

Alichem

Product number: 92050163
Product name: 5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-amine
Packaging: 5g
Price: $909
Updated: 2021/12/16

More

Less

5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-ylamine Chemical Properties,Usage,Production

Synthesis

102121-55-1

92050-16-3

General procedure for the synthesis of 5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-amine (74) from 2-nitro-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-amine (73): 1,1,4,4-tetramethyl-6-nitro-1,2,3,4-tetrahydronaphthalene (73) (2.5 g, 10.7 mmol) was dissolved in ethyl acetate (210 mL) in ethyl acetate using 10% Pd/C as a catalyst, and the hydrogenation reaction was repeated twice at a flow rate of 1.0 mL/min in a ThalesNano H-Cubereactor at 70°C and 2-5 bar hydrogen pressure. Upon completion of the reaction, the reaction solution was concentrated in vacuum to afford a yellow crystalline solid 5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-amine (74) (2.1532 g, 99% yield), with a melting point of 205°C. The product was characterized as follows: 1H NMR (400 MHz, CDCl3) δ 7.11 (d, J = 8.4 Hz, 1H), 6.65 (d, J = 2.4 Hz, 1H), 6.54 (dd, J = 8.4, 2.4 Hz, 1H), 3.62 (br s, 2H), 1.66 (s, 4H), 1.26 (s, 6H), 1.25 (s, 6H); 13C NMR (100.6 MHz, CDCl3) δ 145.8, 143.3, 135.4, 127.3, 113.7, 112.9, 35.2, 34.1, 33.5, 31.9, 31.7; IR (neat) 3405, 3208, 2952, 2920, 1612, 1499 cm-1; LC-MS (CI) m/z (M+H)+ Calculated C14H22N 204.1752, Measured C14H22N 204.1752. 204.1747.

References

[1] Bioorganic and Medicinal Chemistry Letters, 2006, vol. 16, # 9, p. 2352 - 2356
[2] Patent: WO2015/130973, 2015, A1. Location in patent: Page/Page column 34; 35
[3] Journal of Medicinal Chemistry, 2016, vol. 59, # 19, p. 8924 - 8940
[4] Patent: US2018/207156, 2018, A1. Location in patent: Paragraph 0114; 0119
[5] Bioorganic and Medicinal Chemistry, 2008, vol. 16, # 15, p. 7277 - 7290

5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-ylamine Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-ylamine Suppliers

China 92 India 2 United States 6 Global 100

Shanghai Synteam Biochem CO.,ltd

Tel: +86-021-58380978 13482386415
Fax: 021-58380978
Email: info@systeambc.com
Country: China
ProdList: 896
Advantage: 50

Shanghai Chengyu Biotechnology Co., Ltd.

Tel: 021-51525055
Email: 309639130@qq.com
Country: China
ProdList: 42
Advantage: 58

Zhengzhou HQ Material Co., Ltd.

Tel: 67759225 13526468238
Email: sale@hqmat.com
Country: China
ProdList: 1343
Advantage: 58

Guangshu Material (Wuhan) Co., Ltd.

Tel: 15071066002
Fax: -
Email: solomlibo@163.com
Country: China
ProdList: 143
Advantage: 55

Mianyang Chemget Chemical Co., Ltd.

Tel: 816-816-2551723 18681628050
Fax: 08162551905
Email: sales@chemget.com.cn
Country: China
ProdList: 97
Advantage: 58

China Langchem Inc.

Tel: 0086-21-58956006
Fax: 0086-21-58956100
Country: China
ProdList: 7811
Advantage: 57

Aemon Chemical

Tel: 0086-755-86198205
Email: acinfo@aemonchem.com
Country: China
ProdList: 1931
Advantage: 57

Shanghai XueEr Pharmaceutical Technology Co., Ltd

Tel: 021-34622192 13917187091
Fax: 86-21-34622765
Email: 1021708276@qq.com
Country: China
ProdList: 81
Advantage: 57

Springchem New Material Technology Co.,Limited

Tel: +86-021-62885108 +8613917661608
Email: info@spring-chem.com
Country: China
ProdList: 2068
Advantage: 57

Suzhou Sibian Chemical Technology Co.,Ltd.

Tel: 0512-65617459 18915409046
Fax: 0512-65617459
Email: sales@sibian-chem.com
Country: China
ProdList: 1922
Advantage: 55

More

Less

View Lastest Price from 5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-ylamine manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-ylamine 92050-16-3
Price: US $2.20-8.80/kg
Min. Order: 1kg
Purity: 99%min
Supply Ability: 1000kg
Release date: 2025-06-13

Shaanxi Dideu New Materials Co. Ltd

Product: 5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-ylamine 92050-16-3
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-03-11

Jiangsu Nata Opto-electronic Material Co.,Ltd.

Product: 5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-ylamine 92050-16-3
Price: US $0.00/g
Min. Order: 100g
Purity: 99%
Supply Ability: 5kg
Release date: 2023-06-01

92050-16-3, 5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-ylamineRelated Search:

5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-ylamine

5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthylamine

2-aMino-5,5,8,8-tetraMethyl-5,6,7,8-tetrahydronaphthalene, 2-aMino-5,6,7,8-tetrahydro-5,5,8,8-tetraMethylnaphthalene

5,5,8,8-TetraMethyl-6,7-dihydronaphthalen-2-aMine

2-Naphthalenamine,5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-

5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-amine

2-Amino-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalene

Tamibarotene Impurity 1

5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-ylamine ISO 9001：2015 REACH

5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-napthylamine

5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-ylamine，98% min

92050-16-3