ChemicalBook > CAS DataBase List > 1-(2-Chloroethyl)pyrrolidine Hydrochloride

1-(2-Chloroethyl)pyrrolidine Hydrochloride

Product Name
1-(2-Chloroethyl)pyrrolidine Hydrochloride
CAS No.
7250-67-1
Chemical Name
1-(2-Chloroethyl)pyrrolidine Hydrochloride
Synonyms
2-Pyrrolidinoethyl;2-chloroethylpyrrolidine;N-Chloroethylpyrprolidine;N-CHLOROETHYL PYRROLIDINE;2-CHLOROETHYLPYRROLIDINE HCL;2-ChloroethylpyrrolidineHcl98%;2-Chloroethylpyrrolidine Hcl 98%;N-(2-Chloroethyl)pyrrolidine HCl;1-(2-CHLOROETHYL)PYRROLIDINE HCL;N-(BETA-CHLOROETHYL)PYRROLIDINE HCL
CBNumber
CB9248483
Molecular Formula
C6H13Cl2N
Formula Weight
170.08
MOL File
7250-67-1.mol
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1-(2-Chloroethyl)pyrrolidine Hydrochloride Property

Melting point:
167-170 °C(lit.)
Boiling point:
237°C(lit.)
Density 
0.4[at 20℃]
vapor pressure 
1.64hPa at 25℃
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Chloroform (Slightly), Water (Slightly)
form 
Crystalline Powder or Crystals
color 
White to off-white
Water Solubility 
Soluble
Sensitive 
Hygroscopic
BRN 
3677061
InChI
InChI=1S/C6H12ClN.ClH/c7-3-6-8-4-1-2-5-8;/h1-6H2;1H
InChIKey
FSNGFFWICFYWQC-UHFFFAOYSA-N
SMILES
N1(CCCl)CCCC1.[H]Cl
LogP
0.736 at 25℃
CAS DataBase Reference
7250-67-1(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-20/22
Safety Statements 
26-36-37/39
WGK Germany 
3
RTECS 
UY0703150
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C42807
Product name
1-(2-Chloroethyl)pyrrolidine hydrochloride
Purity
98%
Packaging
25g
Price
$144
Updated
2024/03/01
Sigma-Aldrich
Product number
C42807
Product name
1-(2-Chloroethyl)pyrrolidine hydrochloride
Purity
98%
Packaging
100g
Price
$210.8
Updated
2024/03/01
TCI Chemical
Product number
C1202
Product name
1-(2-Chloroethyl)pyrrolidine Hydrochloride
Purity
>98.0%(T)
Packaging
25g
Price
$30
Updated
2024/03/01
Alfa Aesar
Product number
B22236
Product name
1-(2-Chloroethyl)pyrrolidine hydrochloride, 98%
Packaging
25g
Price
$48.65
Updated
2024/03/01
Alfa Aesar
Product number
B22236
Product name
1-(2-Chloroethyl)pyrrolidine hydrochloride, 98%
Packaging
100g
Price
$137.65
Updated
2024/03/01
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1-(2-Chloroethyl)pyrrolidine Hydrochloride Chemical Properties,Usage,Production

Chemical Properties

white to off-white crystals or crystalline powder

Uses

1-(2-Chloroethyl)pyrrolidine is a haloalkyl substituted pyrrolidine used in the preparation of various pharmaceutical compound such as the estrogen receptor antagonist Nafoxidine (N212800) and its analogues.

Uses

1-(2-Chloroethyl)pyrrolidine is a haloalkyl substituted pyrrolidine used in the preparation of various pharmaceutical compound such as the estrogen receptor antagonist Nafoxidine (N212800) and its ana logues.

Purification Methods

Purify the hydrochloride by recrystallisation from isopropanol/di-isopropyl ether (charcoal) and recrystallise it twice more. The free base, b 55-56o/11mm, 60-63o/23mm and 90o/56mm, is relatively unstable and should be converted to the hydrochloride immediately, by dissolving in isopropanol and bubbling dry HCl through the solution at 0o, filtering off the hydrochloride and recrystallising it. The picrate has m 107.3-107.8o (from EtOH) [Cason J Org Chem 24 247 1959, Wright et al. J Am Chem Soc 70 3098 1948]. [Beilstein 20 III/IV 66.]

1-(2-Chloroethyl)pyrrolidine Hydrochloride Preparation Products And Raw materials

Raw materials

Acetonitrile Potassium carbonate Chloroform 2-Chloroethanol Hydrochloric acid Dichloromethane Diisopropyl ether Isopropyl alcohol Thionyl chloride Sulfuric acid Pyrrolidine

Preparation Products

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View Lastest Price from 1-(2-Chloroethyl)pyrrolidine Hydrochloride manufacturers

airuikechemical co., ltd.
Product
1-(2-chloroethyl) pyrrolidine hydrochloride 7250-67-1
Price
US $0.00-0.00/Kg
Min. Order
1Kg
Purity
99.9%
Supply Ability
200tons
Release date
2024-04-09
Hebei Yanxi Chemical Co., Ltd.
Product
1-(2-Chloroethyl)pyrrolidine Hydrochloride 7250-67-1
Price
US $40.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
30 tons
Release date
2024-03-11
Henan Aochuang Chemical Co.,Ltd.
Product
1-(2-Chloroethyl)pyrrolidine Hydrochloride 7250-67-1
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2022-10-13

7250-67-1, 1-(2-Chloroethyl)pyrrolidine HydrochlorideRelated Search:

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