3-(3-bromophenyl)Pyridine
- Product Name
- 3-(3-bromophenyl)Pyridine
- CAS No.
- 4422-32-6
- Chemical Name
- 3-(3-bromophenyl)Pyridine
- Synonyms
- 3-(m-Bromophenyl)pyridine;3-(3-bromophenyl)Pyridine;3-(3-bromophenenyl)pyridine;Pyridine, 3-(3-bromophenyl)-;3-(3-Bromophenyl)pyridine>
- CBNumber
- CB92489596
- Molecular Formula
- C11H8BrN
- Formula Weight
- 234.09
- MOL File
- 4422-32-6.mol
3-(3-bromophenyl)Pyridine Property
- Boiling point:
- 321℃
- Density
- 1.426
- refractive index
- 1.6420 to 1.6460
- Flash point:
- 148℃
- storage temp.
- Store at room temperature
- pka
- 4.78±0.10(Predicted)
- form
- clear liquid
- color
- Light yellow to Yellow to Orange
Safety
- HS Code
- 2933.39.9200
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- B4865
- Product name
- 3-(3-Bromophenyl)pyridine
- Purity
- >98.0%(GC)(T)
- Packaging
- 1g
- Price
- $63
- Updated
- 2025/07/31
- Product number
- B4865
- Product name
- 3-(3-Bromophenyl)pyridine
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $190
- Updated
- 2025/07/31
- Product number
- B700670
- Product name
- 3-(3-Bromophenyl)pyridine
- Packaging
- 500mg
- Price
- $200
- Updated
- 2021/12/16
- Product number
- B700670
- Product name
- 3-(3-Bromophenyl)pyridine
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- B700670
- Product name
- 3-(3-Bromophenyl)pyridine
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
3-(3-bromophenyl)Pyridine Chemical Properties,Usage,Production
Uses
3-(3-Bromophenyl)pyridine is commonly used as a reactant in the process for the synthesis of compounds such as 11H-?indeno[1,?2-?b]?quinoline derivatives which are used for the manufacturing of OLED (organic light emitting devices).
Synthesis
591-18-4
1692-25-7
4422-32-6
The general procedure for the synthesis of 3-(3-bromophenyl)pyridine from 1-bromo-3-iodobenzene and pyridine-3-boronic acid was as follows: 1-bromo-3-iodobenzene (1.118 g, 3.95 mmol) and pyridine-3-boronic acid (0.559 g, 4.54 mmol) were added to a 100 mL three-necked round-bottomed flask. Dioxane (20 mL) and 2N K2CO3 aqueous solution (20 mL) were added to the flask. The reaction mixture was stirred and degassed with argon for 30 minutes. Subsequently, tetrakis(triphenylphosphine)palladium (50 mg, 0.04 mmol, 1 mol%) was added under argon protection. The reaction mixture was heated to 100 °C and stirred overnight. Upon completion of the reaction, the solvent was removed by rotary evaporation. The residue was suspended in a solvent mixture of water (50 mL) and dichloromethane (50 mL). The organic layer was separated and washed with brine (50 mL x 3). The organic layer was dried with anhydrous Na2SO4 and after filtration to remove the desiccant, it was concentrated to give about 0.92 g of 3-(3-bromophenyl)pyridine in 100% yield. The product was characterized by 1H NMR (400 MHz, CDCl3): δ 8.85 (s, 1H), 8.65 (d, 1H), 7.87 (d, 1H), 7.75 (s, 1H), 7.57-7.52 (m, 2H), 7.41-7.35 (m, 2H).
References
[1] Patent: US2010/331547, 2010, A1. Location in patent: Page/Page column 13
[2] Patent: WO2014/130597, 2014, A1. Location in patent: Page/Page column 59; 60
[3] Patent: US2009/289547, 2009, A1. Location in patent: Page/Page column 36
[4] Patent: WO2011/11712, 2011, A1. Location in patent: Page/Page column 40-41
[5] Journal of Medicinal Chemistry, 2013, vol. 56, # 11, p. 4181 - 4205
3-(3-bromophenyl)Pyridine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-(3-bromophenyl)Pyridine manufacturers
- Product
- 3-(3-bromophenyl)Pyridine 4422-32-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1ton
- Release date
- 2018-08-06