2,8-diazaspiro[4.5]decane
- Product Name
- 2,8-diazaspiro[4.5]decane
- CAS No.
- 176-67-0
- Chemical Name
- 2,8-diazaspiro[4.5]decane
- Synonyms
- 2,8-diazaspiro[4.5]decane
- CBNumber
- CB92489864
- Molecular Formula
- C8H16N2
- Formula Weight
- 140.23
- MOL File
- 176-67-0.mol
2,8-diazaspiro[4.5]decane Property
- Boiling point:
- 229℃
- Density
- 1.00
- Flash point:
- 113℃
- storage temp.
- 2-8°C
- pka
- 11.12±0.20(Predicted)
- Appearance
- Light yellow to yellow Solid-Liquid Mixture
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- D679818
- Product name
- 2,8-Diazaspiro[4.5]decane
- Packaging
- 50mg
- Price
- $220
- Updated
- 2021/12/16
- Product number
- CHM0097193
- Product name
- 2,8-DIAZASPIRO[4.5]DECANE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $503.33
- Updated
- 2021/12/16
- Product number
- 9264AA
- Product name
- 2,8-Diazaspiro[4.5]decane
- Packaging
- 1g
- Price
- $1458
- Updated
- 2021/12/16
- Product number
- 176670
- Product name
- 2,8-Diazaspiro[4.5]decane
- Packaging
- 250mg
- Price
- $384.16
- Updated
- 2021/12/16
- Product number
- CD11231274
- Product name
- 2,8-Diazaspiro[4.5]decane
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $392
- Updated
- 2021/12/16
2,8-diazaspiro[4.5]decane Chemical Properties,Usage,Production
Synthesis
First, the construction of the 2,8-diazaspiro[4.5]decane core skeleton typically involves the reaction of an N-protected 4-piperidinone with a reagent such as a cyanoacetate or malonic acid ester to form a spirocyclic succinimide structure, namely 2,8-diazaspiro[4.5]decane-1,3-dione, through a series of steps (such as Knoevenagel condensation, hydrolysis, and cyclization). Once the dione intermediate is formed, it can be reduced with a strong reducing agent (such as lithium aluminum hydride) to give the final 2,8-diazaspiro[4.5]decane, which converts the two carbonyl groups on the succinimide ring to methylene groups while removing the protecting group on the nitrogen atom (if present), thus effectively yielding the target spirocyclic diamine compound.
2,8-diazaspiro[4.5]decane Preparation Products And Raw materials
Raw materials
Preparation Products
2,8-diazaspiro[4.5]decane Suppliers
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