Indole alkaloid

Product Name: Indole alkaloid
CAS No.: 642-18-2
Chemical Name: Indole alkaloid
Synonyms: Aids002662;Aids-002662;3,4,5,6,16,17-Hexadehydro-16-(methoxycarbonyl)-19.alpha.-methyl-20.alpha.- oxayohimbanium;Oxayohimbanium,3,4,5,6,16,17-hexadehydro-16-(methoxycarbonyl)-19-methyl-, inner salt, (19a,20a)-
CBNumber: CB92493188
Molecular Formula: C21H20N2O3
Formula Weight: 348.4
MOL File: 642-18-2.mol

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Indole alkaloid Property

storage temp.: Store at -20°C
solubility: Soluble in DMSO
form: Solid
color: White to yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: PXT0002558
Product name: ALSTONINE
Purity: 95.00%
Packaging: 5MG
Price: $498.96
Updated: 2021/12/16

ChemScene

Product number: CS-0078920
Product name: Alstonine
Packaging: 5mg
Price: $1200
Updated: 2021/12/16

Arctom

Product number: CFN97709
Product name: Alstonine
Purity: ≥98%
Packaging: 5mg
Price: $448
Updated: 2021/12/16

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Indole alkaloid Chemical Properties,Usage,Production

Definition

ChEBI: Alstonine is an indole alkaloid with formula C21H20N2O3, isolated from several Rauvolfia species and exhibits antipsychotic activity. It has a role as an antipsychotic agent. It is a methyl ester, an organic heteropentacyclic compound, a zwitterion and an indole alkaloid. It is a conjugate base of an alstonine(1+).

Biological Activity

Alstonine is the main indole alkaloid compound of a botanical drug. Alstonine has antipsychotic, anxiolytic, anticancer and antimalarial properties.

in vitro

Alstonine has the capacity to distinguish cancer DNA from healthy tissue DNA; it inhibits DNA in vitro synthesis when DNA from different cancerous tissues or cells is used as template. Practically without effects on DNA from healthy tissues.

in vivo

In mice models Alstonine shows a clear, dose-dependent, potent antipsychotic profile. Alstonine (ip) prevents amphetamine-induced lethality, with active doses within the range of 0.5-2.0 mg/kg.
Alstonine (0.1, 0.5 and 1.0 mg/kg) prevents MK-801 induced hyperlocomotion. Because Alstonine partially reverses MK-801-induced increase in locomotion both at the hole-board and locomotor activity cages.
Alstonine successfully treats a relatively important proportion of BALB/C mice inoculated with transplantable YC8 lymphoma ascites cells as well as Swiss mice bearing Ehrlich ascites carcinoma cells.

Indole alkaloid Preparation Products And Raw materials

Raw materials

Preparation Products

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Indole alkaloid Suppliers

China 25 United States 5 Global 30

ALB Technology Limited

Tel: 702-983-3769
Fax: 702-983-3769
Email: sales@albtechnology.com
Country: United States
ProdList: 2993
Advantage: 55

EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
ProdList: 8447
Advantage: 60

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32079
Advantage: 58

Quality Phytochemicals LLC

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Email: sales@qualityphytochemicalsllc.com
Country: United States
ProdList: 1461
Advantage: 50

MedChemExpress

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Email: sales@medchemexpress.com
Country: United States
ProdList: 6398
Advantage: 58

642-18-2, Indole alkaloidRelated Search:

Aids002662

Aids-002662

3,4,5,6,16,17-Hexadehydro-16-(methoxycarbonyl)-19.alpha.-methyl-20.alpha.- oxayohimbanium

Oxayohimbanium,3,4,5,6,16,17-hexadehydro-16-(methoxycarbonyl)-19-methyl-, inner salt, (19a,20a)-

642-18-2