7-Bromo-2,3-dihydro-[1,4]dioxino[2,3-b]pyridine
- Product Name
- 7-Bromo-2,3-dihydro-[1,4]dioxino[2,3-b]pyridine
- CAS No.
- 95897-49-7
- Chemical Name
- 7-Bromo-2,3-dihydro-[1,4]dioxino[2,3-b]pyridine
- Synonyms
- 7-Brom-pyrido<2,3-b><1,4>dioxen;7-broMo-2H,3H-[1,4]dioxino[2,3-b]pyridine;7-Bromo-2,3-dihydro-[1,4]dioxino[2,3-b]pyridine;1,4-Dioxino[2,3-b]pyridine, 7-bromo-2,3-dihydro-
- CBNumber
- CB92499115
- Molecular Formula
- C7H6BrNO2
- Formula Weight
- 216.03
- MOL File
- 95897-49-7.mol
7-Bromo-2,3-dihydro-[1,4]dioxino[2,3-b]pyridine Property
- Boiling point:
- 272.5±40.0 °C(Predicted)
- Density
- 1.690±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- form
- solid
- pka
- 2.42±0.20(Predicted)
- Appearance
- Off-white to light yellow Solid
Safety
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 2934999090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- ADE000018
- Product name
- 7-Bromo-2,3-dihydro-[1,4]dioxino[2,3-b]pyridine
- Purity
- Aldrich
- Packaging
- 1g
- Price
- $817
- Updated
- 2025/07/31
- Product number
- B691353
- Product name
- 7-Bromo-2,3-dihydro-[1,4]dioxino[2,3-b]pyridine
- Packaging
- 50mg
- Price
- $130
- Updated
- 2021/12/16
- Product number
- 055513
- Product name
- 7-Bromo-2,3-dihydro-[1,4]dioxino[2,3-b]pyridine
- Packaging
- 100mg
- Price
- $159
- Updated
- 2021/12/16
- Product number
- OR965152
- Product name
- 7-Bromo-2,3-dihydro-[1,4]dioxino[2,3-b]pyridine
- Purity
- 97%
- Packaging
- 100mg
- Price
- $160
- Updated
- 2021/12/16
- Product number
- OR965152
- Product name
- 7-Bromo-2,3-dihydro-[1,4]dioxino[2,3-b]pyridine
- Purity
- 97%
- Packaging
- 250mg
- Price
- $230
- Updated
- 2021/12/16
7-Bromo-2,3-dihydro-[1,4]dioxino[2,3-b]pyridine Chemical Properties,Usage,Production
Synthesis
34206-49-0
106-93-4
95897-49-7
To a suspension of DMF (150 mL) containing 5-bromo-2,3-dihydroxypyridine (10.0 g, 52.63 mmol, CAS 34206-49-0), K2CO3 (21.78 g, 158 mmol) and 1,2-dibromoethane (11.87 g, 63.2 mmol) were added sequentially. The reaction mixture was heated to 100 °C and the reaction was stirred at this temperature for 5 hours. After completion of the reaction, the mixture was cooled to room temperature and subsequently poured into ice water. The reaction mixture was extracted with EtOAc to separate the organic and aqueous phases. The aqueous phase was further extracted with EtOAc and all organic phases were combined. The organic phase was dried with anhydrous Na2SO4, filtered and concentrated under reduced pressure to give the crude product. The crude product was purified by silica gel column chromatography with the eluent being a petroleum ether solution of 10% ethyl acetate. Finally, 2.2 g (18% yield) of pure 6-bromo-[1,3]dioxolo[4,5-b]pyridine was obtained, and its structure was confirmed by 1H NMR (400 MHz, DMSO): δ 7.85 (d, 1H, J=2Hz), 7.59 (d, 1H, J=2Hz), 4.41 (m, 2H), 4.27 (m, 2H).
References
[1] Patent: US2013/12530, 2013, A1. Location in patent: Paragraph 0186
[2] Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, 1984, vol. 39, # 11, p. 1598 - 1606
[3] Patent: US2010/280013, 2010, A1. Location in patent: Page/Page column 45
7-Bromo-2,3-dihydro-[1,4]dioxino[2,3-b]pyridine Preparation Products And Raw materials
Raw materials
Preparation Products
7-Bromo-2,3-dihydro-[1,4]dioxino[2,3-b]pyridine Suppliers
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 021-50795510 4000665055
- Fax
- 021-50795055
- sales@accelachem.com
- Country
- China
- ProdList
- 11035
- Advantage
- 64
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
- Country
- China
- ProdList
- 42934
- Advantage
- 64
- Tel
- 18270980682
- Fax
- 021 51613951
- mlcheng@sunwaypharm.cn
- Country
- China
- ProdList
- 8669
- Advantage
- 57
- Tel
- 021-58170097
- info@topbiochem.com
- Country
- China
- ProdList
- 9510
- Advantage
- 58
- Tel
- 150-2103-5486 18017383231
- Fax
- qq：2817624287
- 983544897@qq.com
- Country
- China
- ProdList
- 9342
- Advantage
- 55
- Tel
- 4009209199
- Fax
- 86-021-52271987
- sales@9dingchem.com
- Country
- China
- ProdList
- 18209
- Advantage
- 56
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 39966
- Advantage
- 60
- Tel
- 15121041756
- xingui2022@126.com
- Country
- China
- ProdList
- 9979
- Advantage
- 58
- Tel
- 微信 17321281695 18019252918
- Fax
- 17321281695
- sale@amkchem.com
- Country
- China
- ProdList
- 15136
- Advantage
- 55
View Lastest Price from 7-Bromo-2,3-dihydro-[1,4]dioxino[2,3-b]pyridine manufacturers
- Product
- 7-Bromo-2,3-dihydro-[1,4]dioxino[2,3-b]pyridine 95897-49-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2020-01-09