ChemicalBook > CAS DataBase List > (4S,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid tert-Butyl Ester

(4S,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid tert-Butyl Ester

Product Name
(4S,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid tert-Butyl Ester
CAS No.
186508-95-2
Chemical Name
(4S,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid tert-Butyl Ester
Synonyms
Atorvastatin Impurity 14;Atorvastatin Impurity 64;Atorvastatin Impurity 93;Atorvastatin calcium impurity 41;Atorvastatin A8 intermediate 4S6R Diastereomer;Atorvastatin Acetonide t-Butyl Ester Side Chain (4S,6R)-Isomer;tert-butyl (4S,6R)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetate;tert-butyl 2-[(4S,6R)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetate;(4S,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid tert-Butyl Ester;(4S,6R)-6-(CyanoMethyl)-2,2-diMethyl-1,3-dioxane-4-acetic Acid 1,1-DiMethylethyl Ester
CBNumber
CB92508084
Molecular Formula
C14H23NO4
Formula Weight
269.34
MOL File
186508-95-2.mol
More
Less

(4S,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid tert-Butyl Ester Property

Boiling point:
364.1±17.0 °C(Predicted)
Density 
1.016±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Oil
color 
Clear Colorless to Yellow
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

TRC
Product number
C981911
Product name
(4S,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-aceticAcidtert-ButylEster
Packaging
500mg
Price
$655
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC20650
Product name
(4S,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic acid tert-butyl ester
Packaging
1mg
Price
$100
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC20650
Product name
(4S,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic acid tert-butyl ester
Packaging
2mg
Price
$150
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC20650
Product name
(4S,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic acid tert-butyl ester
Packaging
5mg
Price
$200
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC20650
Product name
(4S,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic acid tert-butyl ester
Packaging
10mg
Price
$300
Updated
2021/12/16
More
Less

(4S,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid tert-Butyl Ester Chemical Properties,Usage,Production

Chemical Properties

Colourless Oil

Uses

Intermediate in the preparation of Atorvastatin 10-Trans (Atorvastatin Impurity AT10)

(4S,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid tert-Butyl Ester Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

(4S,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid tert-Butyl Ester Suppliers

Canada 1 China 34 India 3 United Kingdom 1 United States 4 Global 43
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14055
Advantage
65
Beijing Comparison Pharmaceutical Technology Co., Ltd
Tel
010-010-52878169 15801002657
Email
sales@bjcomparison.com
Country
China
ProdList
4991
Advantage
58
Hubei XinyuanShun Chemical Co., Ltd.
Tel
13971561712, 13995564702, 027-50664929
Fax
027-50664927
Email
hbeixys2001@163.com
Country
China
ProdList
3120
Advantage
55
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
18042
Advantage
56
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15178
Advantage
58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 18112977050
Email
cb6@aikonchem.com
Country
China
ProdList
16684
Advantage
50
Nanjing XiZe Biotechnology CO., Ltd.
Tel
025-66023220 0086-15250997978
Fax
025-58362220
Email
1511893459@qq.com
Country
China
ProdList
7850
Advantage
55
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9923
Advantage
65

186508-95-2, (4S,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid tert-Butyl EsterRelated Search:

Atorvastatin IMpurity 8 (1R,3S)-1-(1,3-Benzodioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester Atorvastatin Related Compound C Atorvastatin IMpurity 3 N,3-Diphenyl-2-(2-methyl-1-oxopropyl)4-oxo-N-benzenebutanamide (Mixture of Diastereomers) Atorvastatin Impurity 16 3S, 5S enantioMer of Atorvastatin CalciuM Atorvastatin Impurity 22 Atorvastatin IMpurity 6 Dihydroxy Diketo Atorvastatin IMpurity 2,3-Dehydroxy Atorvastatin Sodium Salt 5-Oxo Atorvastatin (4S-cis)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester 3-Oxo Atorvastatin Ortho-Hydroxy atorvastatin calcium salt Difluoro Atorvastatin Acetonide tert-Butyl Ester 2-[1,2-Bis-(4-fluoro-phenyl)-2-oxo-ethyl]-4-methyl-3-oxo-pentanoic acid phenylamide Atorvastatin Dehydro Lactone

  • (4S,6R)-6-(CyanoMethyl)-2,2-diMethyl-1,3-dioxane-4-acetic Acid 1,1-DiMethylethyl Ester
  • (4S-trans)-6-(CyanoMethyl)-2,2-diMethyl-1,3-dioxane-4-acetic Acid 1,1-DiMethylethyl Est
  • (4S,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid tert-Butyl Ester
  • Atorvastatin Impurity 14
  • Atorvastatin Acetonide t-Butyl Ester Side Chain (4S,6R)-Isomer
  • Atorvastatin Impurity 64
  • Atorvastatin A8 intermediate 4S6R Diastereomer
  • tert-butyl (4S,6R)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetate
  • tert-butyl 2-[(4S,6R)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetate
  • (4S,6R)-1,3-Dioxane-4-acetic acid, 6-(cyanomethyl)-2,2-dimethyl-, 1,1-dimethylethyl ester
  • 1,3-Dioxane-4-acetic acid, 6-(cyanomethyl)-2,2-dimethyl-, 1,1-dimethylethyl ester, (4S,6R)-
  • Atorvastatin Impurity 93
  • Atorvastatin calcium impurity 41
  • 186508-95-2
  • Chiral Reagents
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals