ChemicalBook > CAS DataBase List > (4S,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid tert-Butyl Ester

(4S,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid tert-Butyl Ester

Product Name
(4S,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid tert-Butyl Ester
CAS No.
186508-95-2
Chemical Name
(4S,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid tert-Butyl Ester
Synonyms
Atorvastatin Impurity 14;Atorvastatin Impurity 64;Atorvastatin Impurity 93;Atorvastatin calcium impurity 41;Atorvastatin A8 intermediate 4S6R Diastereomer;Atorvastatin Acetonide t-Butyl Ester Side Chain (4S,6R)-Isomer;tert-butyl (4S,6R)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetate;tert-butyl 2-[(4S,6R)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetate;(4S,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid tert-Butyl Ester;(4S,6R)-6-(CyanoMethyl)-2,2-diMethyl-1,3-dioxane-4-acetic Acid 1,1-DiMethylethyl Ester
CBNumber
CB92508084
Molecular Formula
C14H23NO4
Formula Weight
269.34
MOL File
186508-95-2.mol
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(4S,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid tert-Butyl Ester Property

Boiling point:
364.1±17.0 °C(Predicted)
Density 
1.016±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Oil
color 
Clear Colorless to Yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
C981911
Product name
(4S,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-aceticAcidtert-ButylEster
Packaging
500mg
Price
$655
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CCH0033546
Product name
TERT-BUTYL-2-((4S,6R)-6-(CYANOMETHYL)-2,2-DIMETHYL-1,3-DIOXAN-4-YL)ACETATE
Purity
95.00%
Packaging
1G
Price
$5729.85
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC20650
Product name
(4S,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic acid tert-butyl ester
Packaging
1mg
Price
$100
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC20650
Product name
(4S,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic acid tert-butyl ester
Packaging
2mg
Price
$150
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC20650
Product name
(4S,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic acid tert-butyl ester
Packaging
5mg
Price
$200
Updated
2021/12/16
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(4S,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid tert-Butyl Ester Chemical Properties,Usage,Production

Chemical Properties

Colourless Oil

Uses

Intermediate in the preparation of Atorvastatin 10-Trans (Atorvastatin Impurity AT10)

(4S,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid tert-Butyl Ester Preparation Products And Raw materials

Raw materials

Preparation Products

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(4S,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid tert-Butyl Ester Suppliers

Canada 1 China 35 India 3 United Kingdom 1 United States 4 Global 44
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186508-95-2, (4S,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid tert-Butyl EsterRelated Search:

Atorvastatin IMpurity 8 (1R,3S)-1-(1,3-Benzodioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester Atorvastatin Related Compound C Atorvastatin IMpurity 3 N,3-Diphenyl-2-(2-methyl-1-oxopropyl)4-oxo-N-benzenebutanamide (Mixture of Diastereomers) Atorvastatin Impurity 16 3S, 5S enantioMer of Atorvastatin CalciuM Atorvastatin Impurity 22 Atorvastatin IMpurity 6 Dihydroxy Diketo Atorvastatin IMpurity 2,3-Dehydroxy Atorvastatin Sodium Salt 5-Oxo Atorvastatin (4S-cis)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester 3-Oxo Atorvastatin Ortho-Hydroxy atorvastatin calcium salt Difluoro Atorvastatin Acetonide tert-Butyl Ester 2-[1,2-Bis-(4-fluoro-phenyl)-2-oxo-ethyl]-4-methyl-3-oxo-pentanoic acid phenylamide Atorvastatin Dehydro Lactone

  • (4S,6R)-6-(CyanoMethyl)-2,2-diMethyl-1,3-dioxane-4-acetic Acid 1,1-DiMethylethyl Ester
  • (4S-trans)-6-(CyanoMethyl)-2,2-diMethyl-1,3-dioxane-4-acetic Acid 1,1-DiMethylethyl Est
  • (4S,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid tert-Butyl Ester
  • Atorvastatin Impurity 14
  • Atorvastatin Acetonide t-Butyl Ester Side Chain (4S,6R)-Isomer
  • Atorvastatin Impurity 64
  • Atorvastatin A8 intermediate 4S6R Diastereomer
  • tert-butyl (4S,6R)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetate
  • tert-butyl 2-[(4S,6R)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetate
  • (4S,6R)-1,3-Dioxane-4-acetic acid, 6-(cyanomethyl)-2,2-dimethyl-, 1,1-dimethylethyl ester
  • 1,3-Dioxane-4-acetic acid, 6-(cyanomethyl)-2,2-dimethyl-, 1,1-dimethylethyl ester, (4S,6R)-
  • Atorvastatin Impurity 93
  • Atorvastatin calcium impurity 41
  • 186508-95-2
  • Chiral Reagents
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals