4-Bromo-3-nitro pyrazole
- Product Name
- 4-Bromo-3-nitro pyrazole
- CAS No.
- 89717-64-6
- Chemical Name
- 4-Bromo-3-nitro pyrazole
- Synonyms
- 4-bromo-5-nitro-1H-pyrazole;4-Bromo-3-nitro pyrazole;3-Nitro-4-bromo pyrazole;44-Bromo-3-nitro pyrazole;1H-Pyrazole, 4-broMo-3-nitro-
- CBNumber
- CB92516311
- Molecular Formula
- C3H2BrN3O2
- Formula Weight
- 191.97
- MOL File
- 89717-64-6.mol
4-Bromo-3-nitro pyrazole Property
- Melting point:
- 197-198℃
- Boiling point:
- 320.1±22.0 °C(Predicted)
- Density
- 2.156
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- pka
- 7.03±0.50(Predicted)
- Appearance
- White to off-white Solid
Safety
- HS Code
- 2933199090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
N-Bromosuccinimide Price
- Product number
- B686553
- Product name
- 4-Bromo-3-nitro-1H-pyrazole
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- OR302098
- Product name
- 4-Bromo-3-nitro-1H-pyrazole
- Packaging
- 1g
- Price
- $82
- Updated
- 2021/12/16
- Product number
- 026204
- Product name
- 4-Bromo-3-nitro-1H-pyrazole
- Packaging
- 1g
- Price
- $83
- Updated
- 2021/12/16
- Product number
- 4H54-9-61
- Product name
- 4-Bromo-3-nitro-1H-pyrazole
- Packaging
- 1g
- Price
- $90
- Updated
- 2021/12/16
- Product number
- CS-W008972
- Product name
- 1H-Pyrazole,4-bromo-3-nitro-
- Purity
- 98.46%
- Packaging
- 1g
- Price
- $55
- Updated
- 2021/12/16
4-Bromo-3-nitro pyrazole Chemical Properties,Usage,Production
Synthesis
26621-44-3
89717-64-6
General procedure for the synthesis of 4-bromo-3-nitropyrazole from 3-nitro-1H-pyrazole: Water (15 mL) was added to a mixed system containing 3-nitro-1H-pyrazole (48a) (1 g, 8.90 mmol) and N-bromosuccinimide (NBS) (1.73 g, 9.70 mmol) at room temperature and the reaction mixture was stirred continuously overnight. The progress of the reaction was monitored by thin-layer chromatography (TLC) and after confirming that the reaction was complete, the reaction solution was diluted with water and subsequently extracted with ethyl acetate. The organic phase was sequentially washed with saturated sodium chloride solution, dried over anhydrous sodium sulfate, concentrated under reduced pressure, and the solvent was removed by rotary evaporation to afford the target compound 4-bromo-3-nitropyrazole (48b) (1.66 g, 93% yield, white solid). Mass spectrometry (ESI) data: m/z 192 [M + H]+.
References
[1] Patent: EP3360878, 2018, A1. Location in patent: Paragraph 0327; 0328
[2] Patent: CN105669558, 2016, A. Location in patent: Paragraph 0057; 0058; 0059; 0060; 0061; 0062; 0063; 0064
[3] Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984, # 1, p. 63 - 67
[4] Patent: EP1382603, 2004, A1. Location in patent: Page 195; 196
[5] Chemical Biology and Drug Design, 2016, vol. 87, # 4, p. 569 - 574
4-Bromo-3-nitro pyrazole Preparation Products And Raw materials
Raw materials
Preparation Products
4-Bromo-3-nitro pyrazole Suppliers
- Tel
- 0838-5675166 15883665058
- Fax
- 0838-5675535
- nbcxkj@126.com
- Country
- China
- ProdList
- 951
- Advantage
- 55
- Tel
- 021-50795510 4000665055
- Fax
- 021-50795055
- marketing@accelachem.com
- Country
- China
- ProdList
- 10977
- Advantage
- 64
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
- Country
- China
- ProdList
- 42934
- Advantage
- 64
- Tel
- 028-85114309 18982182443
- yangli@happysyn.com
- Country
- China
- ProdList
- 2220
- Advantage
- 55
- Tel
- 021-58170097 15801866362;
- info@topbiochem.com
- Country
- China
- ProdList
- 9520
- Advantage
- 58
- Tel
- +86-21-60341587
- Fax
- +86-21-61294319
- sales@topbiochem.com
- Country
- China
- ProdList
- 6175
- Advantage
- 58
- Tel
- 150-2103-5486 18017383231
- Fax
- qq：2817624287
- 983544897@qq.com
- Country
- China
- ProdList
- 9341
- Advantage
- 55
- Tel
- +86-021-50935922
- Fax
- +86-021-33847795
- Country
- China
- ProdList
- 7865
- Advantage
- 55
- Tel
- 020-39119399 18927568969
- Fax
- 020-39119999
- isunpharm@qq.com
- Country
- China
- ProdList
- 4769
- Advantage
- 55
- Tel
- 020-82185713,82185709 13418171485
- Fax
- 020-82185696
- sales@chem-stone.com
- Country
- China
- ProdList
- 744
- Advantage
- 56
View Lastest Price from 4-Bromo-3-nitro pyrazole manufacturers
- Product
- 4-Bromo-3-nitro pyrazole 89717-64-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%-99.9%
- Supply Ability
- 200KG
- Release date
- 2020-01-07