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6-bromoimidazo[1,5-a]pyridine

Product Name
6-bromoimidazo[1,5-a]pyridine
CAS No.
1239880-00-2
Chemical Name
6-bromoimidazo[1,5-a]pyridine
Synonyms
6-Bromoimidazo[1,5-a<;6-bromoimidazo[1,5-a]pyridine;Imidazo[1,5-a]pyridine, 6-bromo-;6-Bromoimidazo[1,5-a]pyridine
CBNumber
CB92517888
Molecular Formula
C7H5BrN2
Formula Weight
197.03
MOL File
1239880-00-2.mol
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6-bromoimidazo[1,5-a]pyridine Property

Melting point:
240-246°C
Density 
1.69±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
6.42±0.30(Predicted)
form 
solid
color 
Brown
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37/38
Safety Statements 
26
WGK Germany 
3
HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
732141
Product name
6-Bromoimidazo[1,5-a]pyridine
Packaging
500mg
Price
$477.48
Updated
2025/07/31
TRC
Product number
B997768
Product name
6-Bromoimidazo[1,5-a]pyridine
Packaging
10mg
Price
$45
Updated
2021/12/16
TRC
Product number
B997768
Product name
6-Bromoimidazo[1,5-a]pyridine
Packaging
50mg
Price
$65
Updated
2021/12/16
Apolloscientific
Product number
OR910029
Product name
6-Bromoimidazo[1,5-a]pyridine
Purity
95%
Packaging
250mg
Price
$97
Updated
2021/12/16
SynQuest Laboratories
Product number
3H32-9-CR
Product name
6-Bromoimidazo[1,5-a]pyridine
Purity
95%
Packaging
250mg
Price
$156
Updated
2021/12/16
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6-bromoimidazo[1,5-a]pyridine Chemical Properties,Usage,Production

Uses

6-Bromoimidazo[1,5-a]pyridine is a useful research chemical. It’s used in the preparation of substituted pyridazines as small mol. splicing modulator compds. for modulating splicing of mRNA.

Synthesis

1239880-13-7

1239880-00-2

To a solution of N-((5-bromopyridin-2-yl)methyl)formamide (1.0 g, 4.6 mmol) in toluene (30 mL) was added phosphorus oxychloride (POCl3, 1.0 mL, 10.9 mmol). The reaction mixture was stirred at 103 °C for 2 h. After completion of the reaction, the mixture was concentrated to dryness under reduced pressure. The residue was dissolved in dichloromethane (DCM), washed sequentially with saturated aqueous sodium bicarbonate (NaHCO3) and brine, and the organic phase was dried with anhydrous sodium sulfate (Na2SO4), filtered and concentrated under reduced pressure. The residue was purified by fast column chromatography to afford the target product 6-bromoimidazo[1,5-A]pyridine (0.5 g, 55% yield) as a yellow solid. m/z 197,199 ([M+H]+) was detected by LC-MS.

References

[1] Patent: WO2016/112088, 2016, A1. Location in patent: Paragraph 0663
[2] Patent: US2010/204214, 2010, A1. Location in patent: Page/Page column 114

6-bromoimidazo[1,5-a]pyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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6-bromoimidazo[1,5-a]pyridine Suppliers

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View Lastest Price from 6-bromoimidazo[1,5-a]pyridine manufacturers

Career Henan Chemical Co
Product
6-bromoimidazo[1,5-a]pyridine 1239880-00-2
Price
US $6.68/KG
Min. Order
1KG
Purity
97%-99%
Supply Ability
1kg-1000kg
Release date
2020-01-10

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