ChemicalBook > CAS DataBase List > 3-[2-[4-(3,4-dimethylphenyl)-1-piperazinyl]ethyl]-2,3-dihydro-1H-isoindol-1-onedihydrochloride

3-[2-[4-(3,4-dimethylphenyl)-1-piperazinyl]ethyl]-2,3-dihydro-1H-isoindol-1-onedihydrochloride

Product Name
3-[2-[4-(3,4-dimethylphenyl)-1-piperazinyl]ethyl]-2,3-dihydro-1H-isoindol-1-onedihydrochloride
CAS No.
210688-56-5
Chemical Name
3-[2-[4-(3,4-dimethylphenyl)-1-piperazinyl]ethyl]-2,3-dihydro-1H-isoindol-1-onedihydrochloride
Synonyms
PD 168568 dihydrochl;PD 168568 dihydrochloride;PD 168568 dihydrochloride, D4 antagonist;1H-Isoindol-1-one, 3-[2-[4-(3,4-dimethylphenyl)-1-piperazinyl]ethyl]-2,3-dihydro-;3-[2-[4-(3,4-dimethylphenyl)-1-piperazinyl]ethyl]-2,3-dihydro-1H-isoindol-1-onedihydrochloride
CBNumber
CB92518845
Molecular Formula
C22H27N3O
Formula Weight
349.47
MOL File
210688-56-5.mol
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3-[2-[4-(3,4-dimethylphenyl)-1-piperazinyl]ethyl]-2,3-dihydro-1H-isoindol-1-onedihydrochloride Property

storage temp. 
Desiccate at RT
solubility 
Soluble to 50 mM in water and to 100 mM in DMSO
form 
Powder
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
3529
Product name
PD168568dihydrochloride
Purity
≥98%(HPLC)
Packaging
10
Price
$147
Updated
2021/12/16
Tocris
Product number
3529
Product name
PD168568dihydrochloride
Purity
≥98%(HPLC)
Packaging
50
Price
$616
Updated
2021/12/16
TRC
Product number
P217703
Product name
PD168568
Packaging
25mg
Price
$230
Updated
2021/12/16
Usbiological
Product number
256188
Product name
PD 168568 dihydrochloride
Packaging
10mg
Price
$409
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0009878
Product name
PD 168568 DIHYDROCHLORIDE
Purity
95.00%
Packaging
5MG
Price
$503.56
Updated
2021/12/16
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3-[2-[4-(3,4-dimethylphenyl)-1-piperazinyl]ethyl]-2,3-dihydro-1H-isoindol-1-onedihydrochloride Chemical Properties,Usage,Production

Uses

PD 168568 is a selective D4 receptor affinity.

in vivo

PD 168568 (3 mg/kg, Oral) has ability to inhibit amphetamine-stimulated locomotor activity in the rat[3].

Animal Model:Rat[1]
Dosage:3 mg/kg
Administration:Oral administration
Result:Inhibited amphetamine (0.5 mg/kg, i.p.) stimulated locomotor activity.

IC 50

D4 Receptor: 8.8 nM (Ki); D2 Receptor: 1842 nM (Ki); D3 Receptor: 2682 nM (Ki)

3-[2-[4-(3,4-dimethylphenyl)-1-piperazinyl]ethyl]-2,3-dihydro-1H-isoindol-1-onedihydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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3-[2-[4-(3,4-dimethylphenyl)-1-piperazinyl]ethyl]-2,3-dihydro-1H-isoindol-1-onedihydrochloride Suppliers

China 21 United Kingdom 1 United States 7 Global 29
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15838
Advantage
69
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
Advantage
60
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44894
Advantage
58
MedBioPharmaceutical Technology Inc
Tel
021-69568360 18916172912
Email
order@med-bio.cn
Country
China
ProdList
8140
Advantage
58
Shanghai Universal Biotech Co.,Ltd
Tel
15921930842 15921930842
Email
yh-wang@univ-bio.com
Country
China
ProdList
25004
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24961
Advantage
58
Chengdu Peter-like Biotechnology Co., Ltd.
Tel
028-81700200 13308200041
Email
2851167782@qq.com
Country
China
ProdList
11146
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58
Santa Cruz Biotechnology Inc
Tel
021-60936350
Email
scbt@scbt.com
Country
China
ProdList
6594
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58
TargetMol Chemicals Inc.
Tel
+17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
19962
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
52923
Advantage
58

210688-56-5, 3-[2-[4-(3,4-dimethylphenyl)-1-piperazinyl]ethyl]-2,3-dihydro-1H-isoindol-1-onedihydrochlorideRelated Search:


  • 3-[2-[4-(3,4-dimethylphenyl)-1-piperazinyl]ethyl]-2,3-dihydro-1H-isoindol-1-onedihydrochloride
  • PD 168568 dihydrochloride
  • 1H-Isoindol-1-one, 3-[2-[4-(3,4-dimethylphenyl)-1-piperazinyl]ethyl]-2,3-dihydro-
  • PD 168568 dihydrochl
  • PD 168568 dihydrochloride, D4 antagonist
  • 210688-56-5
  • C22H27N3O2HCl
  • C22H29Cl2N3O