ChemicalBook > CAS DataBase List > N-[2-[[(3R)-1-[(4-chlorophenyl)methyl]-3-pyrrolidinyl]amino]-2-oxoethyl]-3-(trifluoromethyl)benzamidehydrochloride

N-[2-[[(3R)-1-[(4-chlorophenyl)methyl]-3-pyrrolidinyl]amino]-2-oxoethyl]-3-(trifluoromethyl)benzamidehydrochloride

Product Name
N-[2-[[(3R)-1-[(4-chlorophenyl)methyl]-3-pyrrolidinyl]amino]-2-oxoethyl]-3-(trifluoromethyl)benzamidehydrochloride
CAS No.
226226-39-7
Chemical Name
N-[2-[[(3R)-1-[(4-chlorophenyl)methyl]-3-pyrrolidinyl]amino]-2-oxoethyl]-3-(trifluoromethyl)benzamidehydrochloride
Synonyms
Teijin compound 1;CCR2 antagonist 4;Teijin compound 1 hydrochloride;(R)-N-(2-((1-(4-Chlorobenzyl)pyrrolidin-3-yl)amino)-2-oxoethyl)-3-(trifluoromethyl)benzamide;N-[2-[[(3R)-1-[(4-chlorophenyl)methyl]pyrrolidin-3-yl]amino]-2-oxo-ethyl]-3-(trifluoromethyl)benzamide;Benzamide, N-[2-[[(3R)-1-[(4-chlorophenyl)methyl]-3-pyrrolidinyl]amino]-2-oxoethyl]-3-(trifluoromethyl)-;N-[2-[[(3R)-1-[(4-chlorophenyl)methyl]-3-pyrrolidinyl]amino]-2-oxoethyl]-3-(trifluoromethyl)benzamidehydrochloride;CCR-2 antagonist 4,CCR2b,CCR,chemokines,chemotaxis,Inhibitor,inhibit,inflammatory,MCP-1,chronic,CCR2 antagonist 4,CC chemokine receptor,Teijin compound1,Teijin compound-1
CBNumber
CB92518850
Molecular Formula
C21H21ClF3N3O2
Formula Weight
439.86
MOL File
226226-39-7.mol
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N-[2-[[(3R)-1-[(4-chlorophenyl)methyl]-3-pyrrolidinyl]amino]-2-oxoethyl]-3-(trifluoromethyl)benzamidehydrochloride Property

Boiling point:
597.9±50.0 °C(Predicted)
Density 
1.37±0.1 g/cm3(Predicted)
storage temp. 
Desiccate at +4°C
solubility 
DMSO: ≥20mg/mL
pka
12.94±0.46(Predicted)
form 
powder
color 
white to tan
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T7330
Product name
Teijin compound 1 hydrochloride
Purity
≥98% (HPLC), powder
Packaging
25mg
Price
$580
Updated
2023/06/20
Sigma-Aldrich
Product number
T7330
Product name
Teijin compound 1 hydrochloride
Purity
≥98% (HPLC), powder
Packaging
5mg
Price
$130
Updated
2022/05/15
Tocris
Product number
3664
Product name
Teijincompound1
Purity
≥98%(HPLC)
Packaging
10
Price
$175
Updated
2021/12/16
Tocris
Product number
3664
Product name
Teijincompound1
Purity
≥98%(HPLC)
Packaging
50
Price
$713
Updated
2021/12/16
Usbiological
Product number
256894
Product name
Teijin compound 1
Packaging
10mg
Price
$508
Updated
2021/12/16
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N-[2-[[(3R)-1-[(4-chlorophenyl)methyl]-3-pyrrolidinyl]amino]-2-oxoethyl]-3-(trifluoromethyl)benzamidehydrochloride Chemical Properties,Usage,Production

Uses

Teijin Compound 1 is a chemokine receptor, CCR2, inhibitor, which reduces sarcoma cell transendothelial migration and metastasis to the lungs.

N-[2-[[(3R)-1-[(4-chlorophenyl)methyl]-3-pyrrolidinyl]amino]-2-oxoethyl]-3-(trifluoromethyl)benzamidehydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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N-[2-[[(3R)-1-[(4-chlorophenyl)methyl]-3-pyrrolidinyl]amino]-2-oxoethyl]-3-(trifluoromethyl)benzamidehydrochloride Suppliers

China 27 United Kingdom 1 United States 8 Global 36
MedChemexpress LLC
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TargetMol Chemicals Inc.
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226226-39-7, N-[2-[[(3R)-1-[(4-chlorophenyl)methyl]-3-pyrrolidinyl]amino]-2-oxoethyl]-3-(trifluoromethyl)benzamidehydrochlorideRelated Search:


  • N-[2-[[(3R)-1-[(4-chlorophenyl)methyl]-3-pyrrolidinyl]amino]-2-oxoethyl]-3-(trifluoromethyl)benzamidehydrochloride
  • Teijin compound 1
  • Teijin compound 1 hydrochloride
  • N-[2-[[(3R)-1-[(4-chlorophenyl)methyl]pyrrolidin-3-yl]amino]-2-oxo-ethyl]-3-(trifluoromethyl)benzamide
  • CCR2 antagonist 4
  • Benzamide, N-[2-[[(3R)-1-[(4-chlorophenyl)methyl]-3-pyrrolidinyl]amino]-2-oxoethyl]-3-(trifluoromethyl)-
  • CCR-2 antagonist 4,CCR2b,CCR,chemokines,chemotaxis,Inhibitor,inhibit,inflammatory,MCP-1,chronic,CCR2 antagonist 4,CC chemokine receptor,Teijin compound1,Teijin compound-1
  • (R)-N-(2-((1-(4-Chlorobenzyl)pyrrolidin-3-yl)amino)-2-oxoethyl)-3-(trifluoromethyl)benzamide
  • 226226-39-7
  • C21H21CIF3O2HCl