7-Quinazolinecarboxylic acid, 2-chloro-, methyl ester

Product Name: 7-Quinazolinecarboxylic acid, 2-chloro-, methyl ester
CAS No.: 953039-79-7
Chemical Name: 7-Quinazolinecarboxylic acid, 2-chloro-, methyl ester
Synonyms: methyl 2-chloroquinazolin...;Methyl 2-chloro-7-quinazolinecarboxylate;Methyl 2-chloroquinazoline-7-carboxylate;Methyl 2-chloro-quinazolin-7-carboxylate;2-Chloro-7-quinazolinecarboxylic acid methyl ester;7-Quinazolinecarboxylic acid, 2-chloro-, Methyl ester
CBNumber: CB92525175
Molecular Formula: C10H7ClN2O2
Formula Weight: 222.63
MOL File: 953039-79-7.mol

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7-Quinazolinecarboxylic acid, 2-chloro-, methyl ester Property

Boiling point:: 328.6±24.0 °C(Predicted)
Density: 1.392±0.06 g/cm3(Predicted)
storage temp.: Storage temp. -20°C
pka: -0.73±0.30(Predicted)
Appearance: Light yellow to light green Solid

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Safety

HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: B499460
Product name: methyl2-chloroquinazoline-7-carboxylate
Packaging: 10mg
Price: $45
Updated: 2021/12/16

ChemScene

Product number: CS-0046212
Product name: Methyl2-chloroquinazoline-7-carboxylate
Purity: >97.0%
Packaging: 100mg
Price: $90
Updated: 2021/12/16

ChemScene

Product number: CS-0046212
Product name: Methyl2-chloroquinazoline-7-carboxylate
Purity: >97.0%
Packaging: 250mg
Price: $150
Updated: 2021/12/16

ChemScene

Product number: CS-0046212
Product name: Methyl2-chloroquinazoline-7-carboxylate
Purity: >97.0%
Packaging: 1g
Price: $395
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H23-5-24
Product name: Methyl 2-chloroquinazoline-7-carboxylate
Packaging: 1g
Price: $500
Updated: 2021/12/16

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7-Quinazolinecarboxylic acid, 2-chloro-, methyl ester Chemical Properties,Usage,Production

Synthesis

953039-78-6

953039-79-7

Step 3. Preparation of methyl 2-chloroquinazoline-7-carboxylate To methyl 2-oxo-1,2-dihydroquinazoline-7-carboxylate (1.0 eq.) was added phosphorous trichloride (POCl3, 3.0 eq.), the reaction mixture was heated to 100 °C and the reaction was stirred at this temperature for 20 minutes. Upon completion of the reaction, the mixture was cooled to room temperature and the reaction was quenched by slowly pouring into ice water. The precipitated solid product was collected by filtration and washed with cold water. The resulting solid was dried overnight under high vacuum to afford methyl 2-chloroquinazoline-7-carboxylate in 60% yield. The product was confirmed by electrospray mass spectrometry (ES/MS), m/z 223 (MH+).

References

[1] Patent: WO2007/117607, 2007, A2. Location in patent: Page/Page column 341

7-Quinazolinecarboxylic acid, 2-chloro-, methyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 7-Quinazolinecarboxylic acid, 2-chloro-, methyl ester manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: Methyl 2-chloroquinazolin... 953039-79-7
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-13

Career Henan Chemical Co

Product: Methyl 2-chloroquinazolin 953039-79-7
Price: US $5.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100KG
Release date: 2020-01-12

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953039-79-7