HX 531

Product Name: HX 531
CAS No.: 188844-34-0
Chemical Name: HX 531
Synonyms: HX 531;HX531 >=98% (HPLC);Retinoic acid receptors,inhibit,RAR/RXR,HX-531,Inhibitor,Retinoid X receptors,HX 531,HX531;4-(7,8,9,10-Tetrahydro-5,7,7,10,10-pentamethyl-2-nitro-5H-benzo[b]naphtho[2,3-e][1,4]diazepin-12-yl)benzoic acid;4-(5,7,7,10,10-Pentamethyl-2-nitro-7,8,9,10-tetrahydro-5H-benzo[b]naphtho[2,3-e][1,4]diazepin-12-yl)benzoic acid;Benzoic acid, 4-(7,8,9,10-tetrahydro-5,7,7,10,10-pentamethyl-2-nitro-5H-benzo[b]naphtho[2,3-e][1,4]diazepin-12-yl)-
CBNumber: CB92535673
Molecular Formula: C29H29N3O4
Formula Weight: 483.56
MOL File: 188844-34-0.mol

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HX 531 Property

Boiling point:: 656.2±55.0 °C(Predicted)
Density: 1.27±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMF:15.0(Max Conc. mg/mL);31.02(Max Conc. mM)
DMF:PBS (pH 7.2) (1:6):0.14(Max Conc. mg/mL);0.29(Max Conc. mM)
DMSO:17.67(Max Conc. mg/mL);36.53(Max Conc. mM)
Ethanol:0.12(Max Conc. mg/mL);0.25(Max Conc. mM)
form: A crystalline solid
pka: 3.70±0.10(Predicted)
color: Light yellow to orange

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML2170
Product name: HX531
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $91.6
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML2170
Product name: HX531
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $371
Updated: 2024/03/01

Cayman Chemical

Product number: 20762
Product name: HX 531
Purity: ≥98%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 20762
Product name: HX 531
Purity: ≥98%
Packaging: 5mg
Price: $86
Updated: 2024/03/01

Cayman Chemical

Product number: 20762
Product name: HX 531
Purity: ≥95%
Packaging: 25mg
Price: $343
Updated: 2024/03/01

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HX 531 Chemical Properties,Usage,Production

Uses

HX 531 is a novel RXR antagonist used to enhance transactivation of PPARγ and ST 13 preadipocyte differentiation. Helps in the reduction of triglyceride content in white adipose tissue, skeletal muscle and liver.

Biological Activity

HX-531 is a potent antagonist of the retinoid X receptor (RXR) with an IC50 value of 18 nM. HX531 has been used in many studies of the various effects of retinoids and RXR activity in diseases such as diabetes, Parkinsonμs disease, often as a control for agonists such as Bexarotene. It was recently shown to promote white adipogenic differentiation and inhibit both basal and Bexarotene-induced brown adipogenic differentiation.

storage

Store at +4°C

HX 531 Preparation Products And Raw materials

Raw materials

Preparation Products

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HX 531 Suppliers

CHINA 51 United Kingdom 1 United States 7 Global 59

Shanghai Boyle Chemical Co., Ltd.

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Email: sales@boylechem.com
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Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
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EMMX Biotechnology LLC

Tel: 888-539-0666
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Email: info@emmx.com
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ShangHai Biochempartner Co.,Ltd

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Shanghai Biopharmaleader Co., Ltd.

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Taizhou Crene Biotechnology Co. Ltd.

Tel: +86-0576-88813233 +86-13396860566
Email: sales@pharm-intermediates.com
Country: China
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TargetMol Chemicals Inc.

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Email: marketing@targetmol.com
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InvivoChem

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Absin Bioscience Inc.

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Jinan Sanyuan Chemical Co. LTD

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188844-34-0, HX 531Related Search:

HX 531

4-(7,8,9,10-Tetrahydro-5,7,7,10,10-pentamethyl-2-nitro-5H-benzo[b]naphtho[2,3-e][1,4]diazepin-12-yl)benzoic acid

HX531 >=98% (HPLC)

Retinoic acid receptors,inhibit,RAR/RXR,HX-531,Inhibitor,Retinoid X receptors,HX 531,HX531

Benzoic acid, 4-(7,8,9,10-tetrahydro-5,7,7,10,10-pentamethyl-2-nitro-5H-benzo[b]naphtho[2,3-e][1,4]diazepin-12-yl)-

4-(5,7,7,10,10-Pentamethyl-2-nitro-7,8,9,10-tetrahydro-5H-benzo[b]naphtho[2,3-e][1,4]diazepin-12-yl)benzoic acid

188844-34-0