trans-CloMiphene Hydrochloride
- Product Name
- trans-CloMiphene Hydrochloride
- CAS No.
- 14158-65-7
- Chemical Name
- trans-CloMiphene Hydrochloride
- Synonyms
- Enclomiphene HCl;EncloMifene Hydrochlor;trans-Clomiphene-d5 HCl;Enclomiphene hydrochloride;(E)-CloMiphene Hydrochloide;(E)-Clomiphene hydrochloride;trans-Clomifene hydrochloride;rans-CloMiphene Hydrochloride;trans-CloMiphene Hydrochloride;(E)-2-[p-(2-chloro-1,2-diphenylvinyl)phenoxy]-triethylaMine Hydrochloride
- CBNumber
- CB92544149
- Molecular Formula
- C26H29Cl2NO
- Formula Weight
- 442.42056
- MOL File
- 14158-65-7.mol
trans-CloMiphene Hydrochloride Property
- Melting point:
- 156.6-158 °C
- storage temp.
- 2-8°C
- solubility
- H2O: soluble10mg/mL, clear
- form
- powder
- color
- white to beige
- Water Solubility
- H2O: 10mg/mL, clear
- Stability:
- Light Sensitive
Safety
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- SML0719
- Product name
- Enclomiphene hydrochloride
- Purity
- ≥96% (HPLC)
- Packaging
- 5mg
- Price
- $113
- Updated
- 2024/03/01
- Product number
- SML0719
- Product name
- Enclomiphene hydrochloride
- Purity
- ≥96% (HPLC)
- Packaging
- 25mg
- Price
- $537
- Updated
- 2024/03/01
- Product number
- C587035
- Product name
- trans-ClomipheneHydrochloride
- Packaging
- 50mg
- Price
- $680
- Updated
- 2021/12/16
- Product number
- 006972
- Product name
- trans-Clomiphene Hydrochloride
- Packaging
- 2.5mg
- Price
- $460
- Updated
- 2021/12/16
- Product number
- FC20503
- Product name
- trans-Clomiphene hydrochloride
- Packaging
- 50mg
- Price
- $901
- Updated
- 2021/12/16
trans-CloMiphene Hydrochloride Chemical Properties,Usage,Production
Uses
Trans isomer of Clomiphene (C587025). Found to be slightly estrogenic and a less potent inhibitor of LH secretion than the cis isomer.
Uses
Trans isomer of Clomiphene (C587025). Found to be slightly estrogenic and a more potent inhibitor of LH secretion than the cis isomer.
Biological Activity
Enclomiphene is a non-steroidal estrogen receptor antagonist th at promotes gonadotropin-dependent testosterone secretion by the testes. Enclomiphene is the trans-isomer of clomiphene, which is about a 60-40 mix of trans (Enclomiphene) and cis (Zuclomiphene). While enclomiphene (trans-clomiphene) is an estrogen antagonist, zuclomiphene (cis-clomiphene) is a mixed agonist, responsible for the estrogenic activity and therefore the common side effects sometimes seen in males. The enclomiphene isomer is responsible for the anti-estrogen activity and the restoration of ones hypothalamic–pituitary–gonadal axis. In recent clinical trials, enclomiphene increased serum LH and FSH with concomitant increases in testosterone in men with secondary hypogonadism. Enclomiphene showed overall better results than testosterone gels, which raise serum testosterone but can lower LH and FSH at the same time.
trans-CloMiphene Hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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