ICA 069673

ChemicalBook > CAS DataBase List > ICA 069673

Product Name: ICA 069673
CAS No.: 582323-16-8
Chemical Name: ICA 069673
Synonyms: ICA 069673;ICA069673;ICA-069673;ICA-069673 >=98% (HPLC);N-(2-Chloropyrimidin-5-yl)-3,4-difluorobenzamide;N-(2-Chloro-5-pyrimidinyl)-3,4-difluorobenzamide;Benzamide, N-(2-chloro-5-pyrimidinyl)-3,4-difluoro-;Potassium Channel,ICA 069673,ICA-069673,KcsA,inhibit,Inhibitor
CBNumber: CB92552603
Molecular Formula: C11H6ClF2N3O
Formula Weight: 269.63
MOL File: 582323-16-8.mol

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ICA 069673 Property

Boiling point:: 358.9±37.0 °C(Predicted)
Density: 1.539±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: DNF:30.0(Max Conc. mg/mL);111.26(Max Conc. mM)
DMSO:36.24(Max Conc. mg/mL);134.4(Max Conc. mM)
Ethanol:30.25(Max Conc. mg/mL);112.18(Max Conc. mM)
pka: 9.47±0.70(Predicted)
form: Powder

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 22995
Product name: ICA 069673
Purity: ≥98%
Packaging: 5mg
Price: $95
Updated: 2024/03/01

Cayman Chemical

Product number: 22995
Product name: ICA 069673
Purity: ≥98%
Packaging: 10mg
Price: $167
Updated: 2024/03/01

Cayman Chemical

Product number: 22995
Product name: ICA 069673
Purity: ≥98%
Packaging: 25mg
Price: $363
Updated: 2024/03/01

Cayman Chemical

Product number: 22995
Product name: ICA 069673
Purity: ≥98%
Packaging: 50mg
Price: $723
Updated: 2024/03/01

Tocris

Product number: 4305
Product name: ICA069673
Purity: ≥99%(HPLC)
Packaging: 25
Price: $386
Updated: 2021/12/16

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ICA 069673 Chemical Properties,Usage,Production

Description

ICA 069673 is a heteromeric K_v7 channel activator. It is selective for K_v7.2/7.3 over K_v7.3/7.5 (EC₅₀s = 0.69 and 14.3 μM, respectively) and also activates K_v7.4, K_v7.5, and heteromeric K_v7.4/7.5 channels in a dose-dependent manner. ICA 069673 has no activity against hERG, Na_v1.5, and K_v7.1 cardiac ion channels (IC₅₀s = >30 μM). Oral administration of ICA 069673 increases latency to first tonic-clonic seizure in the rat maximal electroshock and pentylentetrazol-induced seizure models (ED₅₀s = 1.5 and <1 mg/kg, respectively). Formulations containing ICA 069673 are under clinical investigation for the treatment of epilepsy.

storage

Room temperature

ICA 069673 Preparation Products And Raw materials

Raw materials

Preparation Products

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ICA 069673 Suppliers

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582323-16-8, ICA 069673Related Search:

ICA 069673

N-(2-Chloro-5-pyrimidinyl)-3,4-difluorobenzamide

ICA069673;ICA-069673

Benzamide, N-(2-chloro-5-pyrimidinyl)-3,4-difluoro-

ICA-069673 >=98% (HPLC)

Potassium Channel,ICA 069673,ICA-069673,KcsA,inhibit,Inhibitor

N-(2-Chloropyrimidin-5-yl)-3,4-difluorobenzamide

582323-16-8

C11H6ClF2N3O

Selective KCNQ2/Q3 potassium channel opener.