(S)-2-(Trifluoromethyl)piperidine Property

Boiling point:

118.4±35.0 °C(Predicted)

Density 

1.161 g/mL at 25 °C

refractive index 

n20/D1.391

Flash point:

26℃

pka

7.74±0.10(Predicted)

optical activity

[α]22/D -14.4°, c = 0.5% in methanol

Safety

Hazard Codes 

Xn,N

Risk Statements 

10-22-36/37/38-50

Safety Statements 

26-36/37/39-45-61

RIDADR 

UN 1993C 3 / PGIII

WGK Germany 

3

HazardClass 

IRRITANT

HS Code 

2933399990

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H226Flammable liquid and vapour

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H400Very toxic to aquatic life

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P273Avoid release to the environment.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

(S)-2-(Trifluoromethyl)piperidine Chemical Properties,Usage,Production

Uses

(S)-2-(Trifluoromethyl)piperidine can be used as a reactant for the synthesis of (1R,2R)-2-((S)-2-(trifluoromethyl)piperidin-1-yl)-1,2-dihydronaphthalen-1-ol by ring-opening reaction of oxabenzonorbornadiene in the presence of iridium catalyst.