H-pyrrolo[1,2-b]pyridazine-6-carboxylic acid
- Product Name
- H-pyrrolo[1,2-b]pyridazine-6-carboxylic acid
- CAS No.
- 118768-13-1
- Chemical Name
- H-pyrrolo[1,2-b]pyridazine-6-carboxylic acid
- Synonyms
- pyrrolo[1,2-b]pyridazine-6-carboxylic acid;H-pyrrolo[1,2-b]pyridazine-6-carboxylic acid
- CBNumber
- CB92560985
- Molecular Formula
- C8H6N2O2
- Formula Weight
- 162.15
- MOL File
- 118768-13-1.mol
H-pyrrolo[1,2-b]pyridazine-6-carboxylic acid Property
- Density
- 1.41±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- -0.15±0.41(Predicted)
- Appearance
- Brown to black Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 295816
- Product name
- Pyrrolo[1,2-b]pyridazine-6-carboxylic acid
- Packaging
- 100.00mg
- Price
- $71
- Updated
- 2026/05/19
- Product number
- 295816
- Product name
- Pyrrolo[1,2-b]pyridazine-6-carboxylic acid
- Packaging
- 250.00mg
- Price
- $171
- Updated
- 2026/05/19
- Product number
- 295816
- Product name
- Pyrrolo[1,2-b]pyridazine-6-carboxylic acid
- Packaging
- 1.00g
- Price
- $666
- Updated
- 2026/05/19
- Product number
- P47888
- Product name
- Pyrrolo[1,2-b]pyridazine-6-carboxylic acid
- Purity
- 95+%
- Packaging
- 100mg
- Price
- $70
- Updated
- 2026/05/06
- Product number
- P47888
- Product name
- Pyrrolo[1,2-b]pyridazine-6-carboxylic acid
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $180
- Updated
- 2026/05/06
H-pyrrolo[1,2-b]pyridazine-6-carboxylic acid Chemical Properties,Usage,Production
Synthesis
249513-32-4
118768-13-1
The general procedure for the synthesis of pyrrolo[1,2-b]pyridazine-6-carboxylic acid from the compound (CAS: 249513-32-4) is as follows: intermediate B8: pyrrolo[1,2-b]pyridazine-6-carboxylic acid 7-tert-butyl 5,6-dimethyl pyrrolo[1,2-b]pyridazine-5,6,7-tricarboxylate was prepared with reference to the method reported by J. Mat. (1999 , 9, 2183-2188, which is incorporated herein by reference in its entirety). This was done as follows: the feedstock compound (3.25 g, 9.72 mmol) was suspended in a solution of water (12 mL) containing KOH (2.727 g, 48.6 mmol), and the reaction mixture was subsequently heated and reacted at 60 °C overnight. Upon completion of the reaction, the mixture was acidified to pH = 1 by addition of concentrated aqueous hydrochloric acid (9.41 mL) and stirring was continued at 80 °C overnight. After the reaction mixture was cooled to room temperature, the precipitate was collected by filtration to afford the target product pyrrolo[1,2-b]pyridazine-6-carboxylic acid (1.52 g, 9.37 mmol, 96% yield). The product was analyzed by mass spectrometry: MS/ESI+ m/z 163.1 [MH]+, retention time Rt = 0.61 min (analytical method A).
References
[1] Patent: US2015/361100, 2015, A1. Location in patent: Paragraph 0303; 0304
H-pyrrolo[1,2-b]pyridazine-6-carboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
H-pyrrolo[1,2-b]pyridazine-6-carboxylic acid Suppliers
- Tel
- 4006356688 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- 400-6009262 15618770481
- Fax
- 021-64823266
- yhx@titansci.com
- Country
- China
- ProdList
- 14100
- Advantage
- 59
- Tel
- 13477084141; 13477084141
- Fax
- +86(27)65566697
- sales@luohuapharm.com
- Country
- China
- ProdList
- 468
- Advantage
- 60
- Tel
- +86 0510-85629785
- Fax
- +86 0510-85625359
- Country
- China
- ProdList
- 2327
- Advantage
- 58
- Tel
- 0510-85629785 18013409632
- Fax
- 051085625359
- sales@reading-chemicals.com
- Country
- China
- ProdList
- 15178
- Advantage
- 58
- Tel
- 微信 17321281695 18019252918
- Fax
- 17321281695
- sale@amkchem.com
- Country
- China
- ProdList
- 14996
- Advantage
- 55
- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
- 3008007409@qq.com
- Country
- China
- ProdList
- 89686
- Advantage
- 60
- Tel
- 微信 17321281695 18019252918
- Fax
- 021-31261685
- sale@amkchem.com
- Country
- China
- ProdList
- 9991
- Advantage
- 55
- Tel
- 025-58851090 15955137747
- Fax
- (6)02557626880
- sales01@aikonchem.com
- Country
- China
- ProdList
- 15949
- Advantage
- 58
- Tel
- 028-84641798 18782128315
- 3302391190@qq.com
- Country
- China
- ProdList
- 5266
- Advantage
- 55