JNJ-10397049

Product Name: JNJ-10397049
CAS No.: 708275-58-5
Chemical Name: JNJ-10397049
Synonyms: JNJ-10397049;JNJ-10397049, CID 9869934;JNJ 10397049; JNJ10397049;1-(2,4-dibromophenyl)-3-((4S,5S)-2,2-dimethyl-4-phenyl-1,3-dioxan-6-yl)urea;1-(2,4-dibromophenyl)-3-[(4S,5S)-2,2-dimethyl-4-phenyl-1,3-dioxan-5-yl]urea;3-(2,4-DIBROMOPHENYL)-1-[(4S,5S)-2,2-DIMETHYL-4-PHENYL-1,3-DIOXAN-5-YL]UREA;N-(2,4-DIBROMOPHENYL)-N'-[(4S,5S)-2,2-DIMETHYL-4-PHENYL-1,3-DIOXAN-5-YL]-UREA;Urea, N-(2,4-dibromophenyl)-N'-[(4S,5S)-2,2-dimethyl-4-phenyl-1,3-dioxan-5-yl]-
CBNumber: CB92563461
Molecular Formula: C19H20Br2N2O3
Formula Weight: 484.18
MOL File: 708275-58-5.mol

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JNJ-10397049 Property

storage temp.: Store at -20°C
solubility: Soluble to 100 mM in DMSO and to 100 mM in ethanol
form: Powder
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 14139
Product name: JNJ-10397049
Purity: ≥98%
Packaging: 1mg
Price: $49
Updated: 2024/03/01

Cayman Chemical

Product number: 14139
Product name: JNJ-10397049
Purity: ≥98%
Packaging: 5mg
Price: $168
Updated: 2024/03/01

Cayman Chemical

Product number: 14139
Product name: JNJ-10397049
Purity: ≥98%
Packaging: 10mg
Price: $238
Updated: 2024/03/01

Tocris

Product number: 4317
Product name: JNJ10397049
Purity: ≥99%(HPLC)
Packaging: 10
Price: $227
Updated: 2021/12/16

Tocris

Product number: 4317
Product name: JNJ10397049
Purity: ≥99%(HPLC)
Packaging: 50
Price: $952
Updated: 2021/12/16

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JNJ-10397049 Chemical Properties,Usage,Production

Uses

JNJ 10397049 is a selective OX2 receptor antagonist that exhibited sleep promoting effects in rats.

in vivo

JNJ-10397049 (10-30 mg/kg) decreases the latency for persistent sleep and increased nonrapid eye movement and rapid eye movement sleep time^[2].
JNJ-10397049 blocks ethanol self-administration, place preference and reinstatement^[3].

Animal Model:	Male Sprague-Dawley rats^[2].
Dosage:	10 mg/kg.
Administration:	Subcutaneous administration.
Result:	Induced a significant reduction in NREM sleep latency and an increase in NREM sleep duration during the first 2 h after administration relative to vehicle treatment.

IC 50

OX₂ Receptor

storage

Store at +4°C

JNJ-10397049 Preparation Products And Raw materials

Raw materials

Preparation Products

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JNJ-10397049 Suppliers

China 47 India 1 United Kingdom 1 United States 9 Global 58

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708275-58-5, JNJ-10397049Related Search:

JNJ-10397049

N-(2,4-DIBROMOPHENYL)-N'-[(4S,5S)-2,2-DIMETHYL-4-PHENYL-1,3-DIOXAN-5-YL]-UREA

3-(2,4-DIBROMOPHENYL)-1-[(4S,5S)-2,2-DIMETHYL-4-PHENYL-1,3-DIOXAN-5-YL]UREA

JNJ-10397049, CID 9869934

1-(2,4-dibromophenyl)-3-[(4S,5S)-2,2-dimethyl-4-phenyl-1,3-dioxan-5-yl]urea

JNJ 10397049; JNJ10397049

Urea, N-(2,4-dibromophenyl)-N'-[(4S,5S)-2,2-dimethyl-4-phenyl-1,3-dioxan-5-yl]-

1-(2,4-dibromophenyl)-3-((4S,5S)-2,2-dimethyl-4-phenyl-1,3-dioxan-6-yl)urea

708275-58-5

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