ChemicalBook > CAS DataBase List > JNJ-10397049

JNJ-10397049

Product Name
JNJ-10397049
CAS No.
708275-58-5
Chemical Name
JNJ-10397049
Synonyms
JNJ-10397049;JNJ-10397049, CID 9869934;JNJ 10397049; JNJ10397049;1-(2,4-dibromophenyl)-3-((4S,5S)-2,2-dimethyl-4-phenyl-1,3-dioxan-6-yl)urea;1-(2,4-dibromophenyl)-3-[(4S,5S)-2,2-dimethyl-4-phenyl-1,3-dioxan-5-yl]urea;3-(2,4-DIBROMOPHENYL)-1-[(4S,5S)-2,2-DIMETHYL-4-PHENYL-1,3-DIOXAN-5-YL]UREA;N-(2,4-DIBROMOPHENYL)-N'-[(4S,5S)-2,2-DIMETHYL-4-PHENYL-1,3-DIOXAN-5-YL]-UREA;Urea, N-(2,4-dibromophenyl)-N'-[(4S,5S)-2,2-dimethyl-4-phenyl-1,3-dioxan-5-yl]-
CBNumber
CB92563461
Molecular Formula
C19H20Br2N2O3
Formula Weight
484.18
MOL File
708275-58-5.mol
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JNJ-10397049 Property

storage temp. 
Store at -20°C
solubility 
Soluble to 100 mM in DMSO and to 100 mM in ethanol
form 
Powder
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
14139
Product name
JNJ-10397049
Purity
≥98%
Packaging
1mg
Price
$49
Updated
2024/03/01
Cayman Chemical
Product number
14139
Product name
JNJ-10397049
Purity
≥98%
Packaging
5mg
Price
$168
Updated
2024/03/01
Cayman Chemical
Product number
14139
Product name
JNJ-10397049
Purity
≥98%
Packaging
10mg
Price
$238
Updated
2024/03/01
Tocris
Product number
4317
Product name
JNJ10397049
Purity
≥99%(HPLC)
Packaging
50
Price
$952
Updated
2021/12/16
Tocris
Product number
4317
Product name
JNJ10397049
Purity
≥99%(HPLC)
Packaging
10
Price
$227
Updated
2021/12/16
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JNJ-10397049 Chemical Properties,Usage,Production

Uses

JNJ 10397049 is a selective OX2 receptor antagonist that exhibited sleep promoting effects in rats.

in vivo

JNJ-10397049 (10-30 mg/kg) decreases the latency for persistent sleep and increased nonrapid eye movement and rapid eye movement sleep time[2].
JNJ-10397049 blocks ethanol self-administration, place preference and reinstatement[3].

Animal Model:Male Sprague-Dawley rats[2].
Dosage:10 mg/kg.
Administration:Subcutaneous administration.
Result:Induced a significant reduction in NREM sleep latency and an increase in NREM sleep duration during the first 2 h after administration relative to vehicle treatment.

IC 50

OX2 Receptor

storage

Store at +4°C

JNJ-10397049 Preparation Products And Raw materials

Raw materials

Preparation Products

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JNJ-10397049 Suppliers

China 47 India 1 United Kingdom 1 United States 9 Global 58
AdooQ BioScience, LLC
Tel
+1 (866) 930-6790
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+1 (866) 333-9607
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info@adooq.com
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United States
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TargetMol Chemicals Inc.
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+1-781-999-5354; +17819995354
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marketing@targetmol.com
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United States
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32435
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InvivoChem
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+1-708-310-1919 +1-13798911105
Fax
708-557-7486
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sales@invivochem.cn
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United States
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TargetMol Chemicals Inc.
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+1-781-999-5354;
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support@targetmol.com
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United States
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39035
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Aladdin Scientific
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tp@aladdinsci.com
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United States
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United States Biological
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sales@advtechind.com
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United States
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ApexBio Technology
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sales@apexbt.com
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United States
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Cayman Chemical Company
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cayman@caymanchem.com
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United States
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United States Biological
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chemicals@usbio.net
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United States
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708275-58-5, JNJ-10397049Related Search:


  • JNJ-10397049
  • N-(2,4-DIBROMOPHENYL)-N'-[(4S,5S)-2,2-DIMETHYL-4-PHENYL-1,3-DIOXAN-5-YL]-UREA
  • 3-(2,4-DIBROMOPHENYL)-1-[(4S,5S)-2,2-DIMETHYL-4-PHENYL-1,3-DIOXAN-5-YL]UREA
  • JNJ-10397049, CID 9869934
  • 1-(2,4-dibromophenyl)-3-[(4S,5S)-2,2-dimethyl-4-phenyl-1,3-dioxan-5-yl]urea
  • JNJ 10397049; JNJ10397049
  • Urea, N-(2,4-dibromophenyl)-N'-[(4S,5S)-2,2-dimethyl-4-phenyl-1,3-dioxan-5-yl]-
  • 1-(2,4-dibromophenyl)-3-((4S,5S)-2,2-dimethyl-4-phenyl-1,3-dioxan-6-yl)urea
  • 708275-58-5
  • api