[(3R)-3-aMino-4-[(3-hexylphenyl)aMino]-4-oxobutyl]-phosphonic acid

Product Name: [(3R)-3-aMino-4-[(3-hexylphenyl)aMino]-4-oxobutyl]-phosphonic acid
CAS No.: 909725-61-7
Chemical Name: [(3R)-3-aMino-4-[(3-hexylphenyl)aMino]-4-oxobutyl]-phosphonic acid
Synonyms: ML056;W146HYDRATE;R-3-amino-4-(3-hexylphenylamino)-4-oxobutylphosphonic acid hydrate;[(3R)-3-aMino-4-[(3-hexylphenyl)aMino]-4-oxobutyl]-phosphonic acid;Phosphonic acid, P-[(3R)-3-amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]-;[(3R)-3-aMino-4-[(3-hexylphenyl)aMino]-4-oxobutyl]-phosphonic acid(CAS#:909725-61-7)
CBNumber: CB92582460
Molecular Formula: C16H27N2O4P
Formula Weight: 342.37
MOL File: 909725-61-7.mol

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[(3R)-3-aMino-4-[(3-hexylphenyl)aMino]-4-oxobutyl]-phosphonic acid Property

Density: 1.233±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: methanol: soluble (with 0.1% TFA)
pka: 2.19±0.10(Predicted)
form: powder
color: off-white

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: W1020
Product name: W146 hydrate
Purity: ≥98% (HPLC)
Packaging: 1mg
Price: $233
Updated: 2024/03/01

Sigma-Aldrich

Product number: W1020
Product name: W146 hydrate
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $923
Updated: 2024/03/01

ApexBio Technology

Product number: B7442
Product name: W146
Packaging: 1mg
Price: $251
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: LIP0000599
Product name: W-146 HYDRATE
Purity: 95.00%
Packaging: 1MG
Price: $709.46
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: LIP0000599
Product name: W-146 HYDRATE
Purity: 95.00%
Packaging: 5MG
Price: $1257.8
Updated: 2021/12/16

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[(3R)-3-aMino-4-[(3-hexylphenyl)aMino]-4-oxobutyl]-phosphonic acid Chemical Properties,Usage,Production

Uses

W146 is a selective antagonists of spingosine-1-phosphate receptor subtype 1.

Definition

ChEBI: [(3R)-3-aMino-4-[(3-hexylphenyl)aMino]-4-oxobutyl]-phosphonic acid is an amino acid amide.

General Description

W146 hydrate functions as an orthosteric antagonist. It is associated with blood lymphopenia and lung edema in mice.

Biochem/physiol Actions

Potent S1P(1) competitive antagonist; Ki = 10-77 nM.

storage

Store at -20°C

[(3R)-3-aMino-4-[(3-hexylphenyl)aMino]-4-oxobutyl]-phosphonic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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[(3R)-3-aMino-4-[(3-hexylphenyl)aMino]-4-oxobutyl]-phosphonic acid Suppliers

China 21 Japan 1 United Kingdom 1 United States 5 Global 28

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909725-61-7, [(3R)-3-aMino-4-[(3-hexylphenyl)aMino]-4-oxobutyl]-phosphonic acidRelated Search:

[(3R)-3-aMino-4-[(3-hexylphenyl)aMino]-4-oxobutyl]-phosphonic acid

[(3R)-3-aMino-4-[(3-hexylphenyl)aMino]-4-oxobutyl]-phosphonic acid(CAS#:909725-61-7)

W146HYDRATE

ML056

R-3-amino-4-(3-hexylphenylamino)-4-oxobutylphosphonic acid hydrate

Phosphonic acid, P-[(3R)-3-amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]-

909725-61-7