ChemicalBook > CAS DataBase List > 16(R)-Iloprost

16(R)-Iloprost

Product Name
16(R)-Iloprost
CAS No.
74843-13-3
Chemical Name
16(R)-Iloprost
Synonyms
16(R)-Iloprost;Parecoxib Impurity 87;HIFJCPQKFCZDDL-GBSCXWAGSA-N;16(R)Iloprost,16(R) Iloprost;Pentanoic acid, 5-[hexahydro-5-hydroxy-4-(3-hydroxy-4-methyl-1-octen-6-ynyl)-2(1H)-pentalenylidene]-, [3aS-[2E,3aα,4α(1E,3R*,4S*),5β,6aα]]- (9CI)
CBNumber
CB92589924
Molecular Formula
C22H32O4
Formula Weight
360.48708
MOL File
74843-13-3.mol
More
Less

16(R)-Iloprost Property

Boiling point:
539.2±50.0 °C(Predicted)
Density 
1.210±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: 30 mg/ml; DMSO: 25 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 1 mg/ml
pka
4.77±0.10(Predicted)
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

H336May cause drowsiness or dizziness

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Cayman Chemical
Product number
13076
Product name
16(R)-Iloprost
Purity
≥98%
Packaging
500μg
Price
$150
Updated
2024/03/01
Cayman Chemical
Product number
13076
Product name
16(R)-Iloprost
Purity
≥98%
Packaging
1mg
Price
$283
Updated
2024/03/01
Cayman Chemical
Product number
13076
Product name
16(R)-Iloprost
Purity
≥98%
Packaging
5mg
Price
$1185
Updated
2024/03/01
TRC
Product number
I267310
Product name
16-(R)-Iloprost
Packaging
5mg
Price
$24750
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
65580
Product name
16-(R)-Iloprost
Packaging
5mg
Price
$23500
Updated
2021/12/16
More
Less

16(R)-Iloprost Chemical Properties,Usage,Production

Description

Iloprost is a second generation structural analog of prostacyclin (PGI2) with about ten-fold greater potency than the first generation stable analogs, typified by carbaprostacyclin. Iloprost binds with equal affinity to the recombinant human IP and EP1 receptors with a Ki value of 11 nM. Most preparations of iloprost contain 16(S) and 16(R) stereoisomers. 16(R)-Iloprost inhibits platelet aggregation with an IC50 value of 65 nM.

Uses

16-(R)-Iloprost is the R-isomer of Iloprost (I267300), a synthetic analogue of Prostacyclin (PGI2) used to treat pulmonary arterial hypertension (PAH), scleroderma, Raynaud''s phenomenon and ischemia.

16(R)-Iloprost Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

16(R)-Iloprost Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Shanghai TaoSu Biochemical Technology Co., Ltd.
Tel
021-33632979
Fax
021-34692979
Email
info@tsbiochem.com
Country
China
ProdList
8073
Advantage
58
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9926
Advantage
65
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9709
Advantage
58
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6870
Advantage
58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 13028896684
Email
sales@rrkchem.com
Country
China
ProdList
55896
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11289
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing@energy-chemical.com
Country
China
ProdList
44941
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24023
Advantage
58
Hubei Qingbei Yunyan Pharmaceutical Technology Co., Ltd
Tel
18162595016
Email
3287908757@qq.com
Country
China
ProdList
9887
Advantage
58

74843-13-3, 16(R)-IloprostRelated Search:


  • 16(R)-Iloprost
  • HIFJCPQKFCZDDL-GBSCXWAGSA-N
  • 16(R)Iloprost,16(R) Iloprost
  • Pentanoic acid, 5-[hexahydro-5-hydroxy-4-(3-hydroxy-4-methyl-1-octen-6-ynyl)-2(1H)-pentalenylidene]-, [3aS-[2E,3aα,4α(1E,3R*,4S*),5β,6aα]]- (9CI)
  • Parecoxib Impurity 87
  • 74843-13-3
  • Chiral Reagents, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals