1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[Methoxy(polyethylene glycol)-2000] (aMMoniuM salt
- Product Name
- 1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[Methoxy(polyethylene glycol)-2000] (aMMoniuM salt
- CAS No.
- 474922-77-5
- Chemical Name
- 1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[Methoxy(polyethylene glycol)-2000] (aMMoniuM salt
- Synonyms
- DSPE-PEG;MW2000;DSPE-mPEG3400;18:0 PEG2000 PE;18:0 PEG3000 PE;18:0 PEG5000 PE;18:0 PEG PE, MW 350;DSPE-PEG-methoxy 2000;DSPE-mPEG,CAS:474922-77-5;MPEG2000-DSPE ammonium salt
- CBNumber
- CB92602632
- Molecular Formula
- (C2H4O)nC43H84NO10P.H3N
- Formula Weight
- 0
- MOL File
- 474922-77-5.mol
1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[Methoxy(polyethylene glycol)-2000] (aMMoniuM salt Property
- storage temp.
- -20°C
- form
- powder
- color
- White to off-white
- InChIKey
- KBXRORNJMUHWKT-UHFFFAOYSA-N
- SMILES
- C(COC(=O)CCCCCCCCCCCCCCCCC)(OC(=O)CCCCCCCCCCCCCCCCC)COP(O)(=O)OCCNC(=O)O{-}CC{+n}OC.N
Safety
- WGK Germany
- WGK 3
- Storage Class
- 6.1D - Non-combustible acute toxic Cat.3
toxic hazardous materials or hazardous materials causing chronic effects - Hazard Classifications
- Acute Tox. 3 Inhalation
Acute Tox. 4 Oral
Aquatic Chronic 3
Carc. 2
Eye Irrit. 2
Repr. 2
Skin Irrit. 2
STOT RE 1
STOT SE 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H331Toxic if inhaled
H336May cause drowsiness or dizziness
H351Suspected of causing cancer
H372Causes damage to organs through prolonged or repeated exposure
- Precautionary statements
-
P201Obtain special instructions before use.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[Methoxy(polyethylene glycol)-2000] (aMMoniuM salt Chemical Properties,Usage,Production
Description
18:0 PEG PE, MW 350 is a PEG-modified phospholipid conjugate used in liposome formation of sterically stabilized liposomes with low reticuloendothelial system uptake and increased circulation duration to target cells.
Uses
18:0 PEG3000 PE or 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-3000] is suitable for fabricating non-supported sensor like quartz crystal microbalance (QCM) odor sensors and in the preparation of holmium nanoparticles.
Uses
18:0 PEG750 PE might be used to PEGylate lipoplexes and to study the feasibility of its entrapment into a solid matrix system for prolonged delivery of siRNA in vaginal mucus.
Uses
18:0 PEG350 PE is suitable for liposome modification.
General Description
The molecular weight and exact mass are averages based on the polydispersity of polyethylene glycol (PEG).
Biochem/physiol Actions
Phosphoethanolamine (PE) serves as a substrate for several phospholipids of the cell membrane. It is associated with phospholipid turnover. PE is also found to prevent tumor progression.
1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[Methoxy(polyethylene glycol)-2000] (aMMoniuM salt Preparation Products And Raw materials
Raw materials
Preparation Products
1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[Methoxy(polyethylene glycol)-2000] (aMMoniuM salt Suppliers
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