ChemicalBook > CAS DataBase List > (S)-ethyl 3-(4-(2,7-naphthyridin-1-ylaMino)phenyl)-2-(2-broMo-3-oxospiro[3.5]non-1-en-1-ylaMino)propanoate

(S)-ethyl 3-(4-(2,7-naphthyridin-1-ylaMino)phenyl)-2-(2-broMo-3-oxospiro[3.5]non-1-en-1-ylaMino)propanoate

Product Name
(S)-ethyl 3-(4-(2,7-naphthyridin-1-ylaMino)phenyl)-2-(2-broMo-3-oxospiro[3.5]non-1-en-1-ylaMino)propanoate
CAS No.
455264-30-9
Chemical Name
(S)-ethyl 3-(4-(2,7-naphthyridin-1-ylaMino)phenyl)-2-(2-broMo-3-oxospiro[3.5]non-1-en-1-ylaMino)propanoate
Synonyms
UCB1184197);Zaurategrast ethyl ester;Zaurategrast Ethyl Ester (CDP323;Zaurategrast ethyl ester (Synonyms: CDP323;L-Phenylalanine, N-(2-bromo-3-oxospiro[3.5]non-1-en-1-yl)-4-(2,7-naphthyridin-1-ylamino)-, ethyl ester;(S)-ethyl 3-(4-(2,7-naphthyridin-1-ylaMino)phenyl)-2-(2-broMo-3-oxospiro[3.5]non-1-en-1-ylaMino)propanoate
CBNumber
CB92623655
Molecular Formula
C28H29BrN4O3
Formula Weight
549.46
MOL File
455264-30-9.mol
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(S)-ethyl 3-(4-(2,7-naphthyridin-1-ylaMino)phenyl)-2-(2-broMo-3-oxospiro[3.5]non-1-en-1-ylaMino)propanoate Property

Melting point:
192.5-195 °C
Boiling point:
698.2±55.0 °C(Predicted)
Density 
1.44±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO: 150 mg/mL (273.00 mM); Water: < 0.1 mg/mL (insoluble)
form 
Solid
pka
4.84±0.30(Predicted)
color 
Yellow to reddish brown
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biorbyt Ltd
Product number
orb573290
Product name
Zaurategrast ethyl ester
Purity
>98%
Packaging
100mg
Price
$986
Updated
2021/12/16
Biorbyt Ltd
Product number
orb573290
Product name
Zaurategrast ethyl ester
Purity
>98%
Packaging
250mg
Price
$1949.9
Updated
2021/12/16
Biorbyt Ltd
Product number
orb573290
Product name
Zaurategrast ethyl ester
Purity
>98%
Packaging
1g
Price
$3876
Updated
2021/12/16
DC Chemicals
Product number
DC20072
Product name
Zaurategrastethylester(CDP323;UCB1184197)
Purity
>98%
Packaging
100mg
Price
$650
Updated
2021/12/16
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(S)-ethyl 3-(4-(2,7-naphthyridin-1-ylaMino)phenyl)-2-(2-broMo-3-oxospiro[3.5]non-1-en-1-ylaMino)propanoate Chemical Properties,Usage,Production

Biological Activity

Zaurategrast ethyl ester (CDP323), an ethyl ester prodrug of CT7758, is an α4β1/α4β7 integrin antagonist for the study of inflammatory and autoimmune diseases.

in vitro

Zaurategrast ethyl ester (CDP323), an ethyl ester prodrug of CT7758, shows some improvements in increasing mass transfer.

target

α4β1/α4β7 integrin

(S)-ethyl 3-(4-(2,7-naphthyridin-1-ylaMino)phenyl)-2-(2-broMo-3-oxospiro[3.5]non-1-en-1-ylaMino)propanoate Preparation Products And Raw materials

Raw materials

Preparation Products

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(S)-ethyl 3-(4-(2,7-naphthyridin-1-ylaMino)phenyl)-2-(2-broMo-3-oxospiro[3.5]non-1-en-1-ylaMino)propanoate Suppliers

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455264-30-9, (S)-ethyl 3-(4-(2,7-naphthyridin-1-ylaMino)phenyl)-2-(2-broMo-3-oxospiro[3.5]non-1-en-1-ylaMino)propanoateRelated Search:

L-Phenylalanine,N-(2-broMo-3-oxospiro[3.5]non-1-en-1-yl)-4-(2,7-naphthyridin-1-ylaMino)-,ethyl ester,sulfate (2:1 DEMETON S

  • UCB1184197)
  • Zaurategrast ethyl ester (Synonyms: CDP323
  • Zaurategrast Ethyl Ester (CDP323
  • Zaurategrast ethyl ester
  • (S)-ethyl 3-(4-(2,7-naphthyridin-1-ylaMino)phenyl)-2-(2-broMo-3-oxospiro[3.5]non-1-en-1-ylaMino)propanoate
  • L-Phenylalanine, N-(2-bromo-3-oxospiro[3.5]non-1-en-1-yl)-4-(2,7-naphthyridin-1-ylamino)-, ethyl ester
  • 455264-30-9