ChemicalBook > CAS DataBase List > 1H-Indole-3-ethanaMine, 6-fluoro-N-[[3-(2,2,3,3-tetrafluoropropoxy)phenyl]Methyl]-

1H-Indole-3-ethanaMine, 6-fluoro-N-[[3-(2,2,3,3-tetrafluoropropoxy)phenyl]Methyl]-

Product Name
1H-Indole-3-ethanaMine, 6-fluoro-N-[[3-(2,2,3,3-tetrafluoropropoxy)phenyl]Methyl]-
CAS No.
467459-31-0
Chemical Name
1H-Indole-3-ethanaMine, 6-fluoro-N-[[3-(2,2,3,3-tetrafluoropropoxy)phenyl]Methyl]-
Synonyms
LU AE58054;LU AE58084;idalopirdine;LU AE58054(Idalopirdine);Idalopirdine(Lu-AE-58054);idalopirdine, 10 mM in DMSO;IDALOPIRDINE;LU AE 58054;LUAE58054;LU AE58054 HYDROCHLORIDE; LU AE 58054 HYDROCHLORIDE;N-[2-(6-Fluoro-1H-indol-3-yl)ethyl]-3-(2,2,3,3-tetrafluoropropoxy)benzylamine;6-fluoro-N-[[3-(2,2,3,3-tetrafluoropropoxy)phenyl]methyl]-1H-Indole-3-ethanamine
CBNumber
CB92625336
Molecular Formula
C20H19F5N2O
Formula Weight
398.37
MOL File
467459-31-0.mol
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1H-Indole-3-ethanaMine, 6-fluoro-N-[[3-(2,2,3,3-tetrafluoropropoxy)phenyl]Methyl]- Property

Boiling point:
500.9±50.0 °C(Predicted)
Density 
1.309±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
25℃: DMSO
form 
Powder
pka
16.63±0.30(Predicted)
color 
white to beige
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
27335
Product name
LU AE58054
Packaging
100mg
Price
$547
Updated
2024/03/01
Cayman Chemical
Product number
27335
Product name
LU AE58054
Packaging
250mg
Price
$1139
Updated
2024/03/01
Cayman Chemical
Product number
27335
Product name
LU AE58054
Packaging
25mg
Price
$153
Updated
2024/03/01
Cayman Chemical
Product number
27335
Product name
LU AE58054
Packaging
50mg
Price
$290
Updated
2024/03/01
Usbiological
Product number
453947
Product name
Lu AE58054
Packaging
5mg
Price
$355
Updated
2021/12/16
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1H-Indole-3-ethanaMine, 6-fluoro-N-[[3-(2,2,3,3-tetrafluoropropoxy)phenyl]Methyl]- Chemical Properties,Usage,Production

Uses

The selective and high affinity 5-?HT6 receptor antagonist Lu AE58054 as promising treatment for cognitive disorders, in particular for Alzheimer’s disease (AD).

Biological Activity

Idalopirdine (Lu AE58054) is an orally available, and potent antagonist of the serotonin 6 (5-HT6) receptor. Idalopirdine has been reported to be highly selective over other G-protein coupled receptors. It has K(d) of 0.2nM for the 5-HT6 receptor with 16-fold selectivity over the 5-HT2A receptor (K(i) 3.2nM) and >100-fold selectivity to all other evaluated targets.

1H-Indole-3-ethanaMine, 6-fluoro-N-[[3-(2,2,3,3-tetrafluoropropoxy)phenyl]Methyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

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1H-Indole-3-ethanaMine, 6-fluoro-N-[[3-(2,2,3,3-tetrafluoropropoxy)phenyl]Methyl]- Suppliers

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View Lastest Price from 1H-Indole-3-ethanaMine, 6-fluoro-N-[[3-(2,2,3,3-tetrafluoropropoxy)phenyl]Methyl]- manufacturers

BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
Product
Lu Ae58054 467459-31-0
Price
US $0.00/g
Min. Order
1g
Purity
More Than 99%
Supply Ability
100kg/Month
Release date
2024-11-13
Career Henan Chemical Co
Product
2-(6-fluoro-1H-indol-3-yl)-N-[[3-(2,2,3,3-tetrafluoropropoxy)phen yl]methyl]ethanamine 467459-31-0
Price
US $1.00/KG
Min. Order
1KG
Purity
Min98% HPLC
Supply Ability
g/kg/ton
Release date
2019-12-23
Career Henan Chemical Co
Product
Lu AE58054 467459-31-0
Price
US $1.00/KG
Min. Order
1KG
Purity
Min98% HPLC
Supply Ability
g/kg/ton
Release date
2019-12-20

467459-31-0, 1H-Indole-3-ethanaMine, 6-fluoro-N-[[3-(2,2,3,3-tetrafluoropropoxy)phenyl]Methyl]-Related Search:


  • LU AE58054
  • N-[2-(6-Fluoro-1H-indol-3-yl)ethyl]-3-(2,2,3,3-tetrafluoropropoxy)benzylamine
  • 6-fluoro-N-[[3-(2,2,3,3-tetrafluoropropoxy)phenyl]methyl]-1H-Indole-3-ethanamine
  • idalopirdine
  • LU AE58084
  • LU AE58054(Idalopirdine)
  • 1H-Indole-3-ethanaMine, 6-fluoro-N-[[3-(2,2,3,3-tetrafluoropropoxy)phenyl]Methyl]-
  • Idalopirdine(Lu-AE-58054)
  • LU AE58054 HYDROCHLORIDE; LU AE 58054 HYDROCHLORIDE
  • 2-(6-fluoro-1H-indol-3-yl)-N-[[3-(2,2,3,3-tetrafluoropropoxy)phen yl]methyl]ethanamine
  • IDALOPIRDINE;LU AE 58054;LUAE58054
  • 5-HT Receptor,Serotonin Receptor,Lu AE-58054,idalopirdine,Inhibitor,inhibit,5-hydroxytryptamine Receptor,Lu AE 58054
  • idalopirdine, 10 mM in DMSO
  • 467459-31-0
  • C20H19F5N2O