4-IsoxazolecarboxaMide, 3-(2-chlorophenyl)-N-(4-chlorophenyl)-N,5-diMethyl-

Product Name: 4-IsoxazolecarboxaMide, 3-(2-chlorophenyl)-N-(4-chlorophenyl)-N,5-diMethyl-
CAS No.: 1197300-24-5
Chemical Name: 4-IsoxazolecarboxaMide, 3-(2-chlorophenyl)-N-(4-chlorophenyl)-N,5-diMethyl-
Synonyms: CCDC;TGR5;CS-1017;MDK00245;TGR5 Receptor Agonist;CCDC(TGR5-Receptor-Agonist);TGR5 Receptor Agonist, >=98%;TGR5 Receptor Agonist(isoxazole);BENZYL (4-CHLORO-1H-PYRROLO[2,3-B]PYRIDIN-1-YL)ACETATE;3-(2-CHLOROPHENYL)-N-(4-CHLOROPHENYL)-N,5-DIMETHYLISOXAZOLE-4-CARBOXAMIDE
CBNumber: CB92627077
Molecular Formula: C18H14Cl2N2O2
Formula Weight: 361.22
MOL File: 1197300-24-5.mol

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4-IsoxazolecarboxaMide, 3-(2-chlorophenyl)-N-(4-chlorophenyl)-N,5-diMethyl- Property

Boiling point:: 541.8±50.0 °C(Predicted)
Density: 1.346±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMF: 50 mg/ml; DMSO: 50 mg/ml; DMSO:PBS (pH 7.2) (1:4): 0.2 mg/ml; Ethanol: 30 mg/ml
form: A crystalline solid
pka: -0.52±0.50(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 16291
Product name: TGR5 Receptor Agonist
Purity: ≥98%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 16291
Product name: TGR5 Receptor Agonist
Purity: ≥98%
Packaging: 5mg
Price: $122
Updated: 2024/03/01

Cayman Chemical

Product number: 16291
Product name: TGR5 Receptor Agonist
Purity: ≥98%
Packaging: 10mg
Price: $214
Updated: 2024/03/01

Cayman Chemical

Product number: 16291
Product name: TGR5 Receptor Agonist
Purity: ≥98%
Packaging: 25mg
Price: $456
Updated: 2024/03/01

Usbiological

Product number: T3662-50
Product name: TGR5 Receptor Agonist
Packaging: 5mg
Price: $493
Updated: 2021/12/16

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4-IsoxazolecarboxaMide, 3-(2-chlorophenyl)-N-(4-chlorophenyl)-N,5-diMethyl- Chemical Properties,Usage,Production

Description

TGR5 receptor agonist is an agonist of the bile acid G protein-coupled receptor TGR5 (EC₅₀s = 31.6-158.5 nM in cell-based assays). It stimulates cAMP formation in HEK293 cells expressing TGR5 (EC₅₀ = 2.3 pM). TGR5 receptor agonist (1 mg/kg) increases glucagon-like peptide 1 (GLP-1) secretion and decreases glucose levels in the hepatic portal vein in dogs when administered in combination with glucose. It also inhibits the cytochrome P450 (CYP) isozymes CYP2C19 and CYP3A4 (IC₅₀s = 316.2 and 1,259 nM, respectively).

4-IsoxazolecarboxaMide, 3-(2-chlorophenyl)-N-(4-chlorophenyl)-N,5-diMethyl- Preparation Products And Raw materials

Raw materials

Preparation Products

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4-IsoxazolecarboxaMide, 3-(2-chlorophenyl)-N-(4-chlorophenyl)-N,5-diMethyl- Suppliers

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View Lastest Price from 4-IsoxazolecarboxaMide, 3-(2-chlorophenyl)-N-(4-chlorophenyl)-N,5-diMethyl- manufacturers

Career Henan Chemical Co

Product: 4-IsoxazolecarboxaMide, 3-(2-chlorophenyl)-N-(4-chlorophenyl)-N,5-diMethyl- 1197300-24-5
Price: US $5.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1ton
Release date: 2019-09-03

1197300-24-5, 4-IsoxazolecarboxaMide, 3-(2-chlorophenyl)-N-(4-chlorophenyl)-N,5-diMethyl-Related Search:

Anti-GPR40

4-IsoxazolecarboxaMide, 3-(2-chlorophenyl)-N-(4-chlorophenyl)-N,5-diMethyl-

TGR5

3-(2-chlorophenyl)-N-(4-chlorophenyl)-N,5-diMethyl-4-IsoxazolecarboxaMide

TGR5 Receptor Agonist

3-(2-CHLOROPHENYL)-N-(4-CHLOROPHENYL)-N,5-DIMETHYLISOXAZOLE-4-CARBOXAMIDE

3-(2-Chlorophenyl)-N-(4-chlorophenyl)-N,5-dimethyl-4-isoxazolecarboxamide TGR5

TGR5 4-IsoxazolecarboxaMide, 3-(2-chlorophenyl)-N-(4-chlorophenyl)-N,5-diMethyl-

TGR5 Receptor Agonist, >=98%

CCDC

BENZYL (4-CHLORO-1H-PYRROLO[2,3-B]PYRIDIN-1-YL)ACETATE

CCDC(TGR5-Receptor-Agonist)

CS-1017

MDK00245

3-(2-Chlorophenyl)-N-(4-chlorophenyl)-N,5-dimethyl-1,2-oxazole-4-carboxamide

TGR5 Receptor Agonist(isoxazole)

1197300-24-5

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