Bavisant

Product Name: Bavisant
CAS No.: 929622-08-2
Chemical Name: Bavisant
Synonyms: BEN-2001;Bavisant;JNJ31001074;JNJ-31001074;JNJ 31001074;Bavisant, 10 mM in DMSO;(4-Cyclopropylpiperazin-1-yl)(4-(morpholinomethyl)phenyl)methanone;Methanone, (4-cyclopropyl-1-piperazinyl)[4-(4-morpholinylmethyl)phenyl]-;JNJ31001074,JNJ 31001074,Neurological disorders,inhibit,Histamine Receptor,attention-deficit hyperactivity disorder,ADHD,cognition,Bavisant,wakefulness,Inhibitor
CBNumber: CB92627365
Molecular Formula: C19H27N3O2
Formula Weight: 329.44
MOL File: 929622-08-2.mol

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Bavisant Property

Boiling point:: 485.2±45.0 °C(Predicted)
Density: 1.220±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form: Powder
pka: 7.66±0.70(Predicted)
color: Light yellow to brown

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: API0013813
Product name: BAVISANT
Purity: 95.00%
Packaging: 5MG
Price: $502.7
Updated: 2021/12/16

Crysdot

Product number: CD31000213
Product name: Bavisant
Purity: 98+%
Packaging: 50mg
Price: $586
Updated: 2021/12/16

Crysdot

Product number: CD31000213
Product name: Bavisant
Purity: 98+%
Packaging: 100mg
Price: $911
Updated: 2021/12/16

Crysdot

Product number: CD31000213
Product name: Bavisant
Purity: 98+%
Packaging: 5mg
Price: $163
Updated: 2021/12/16

Crysdot

Product number: CD31000213
Product name: Bavisant
Purity: 98+%
Packaging: 10mg
Price: $247
Updated: 2021/12/16

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Bavisant Chemical Properties,Usage,Production

Uses

Bavisant (JNJ-31001074) is an orally active, potent, brain-penetrating and highly selective antagonist of the histamine H3 receptor. Bavisant can be used for attention-deficit hyperactivity disorder (ADHD) research[1][2][3].

in vivo

Bavisant increases acetylcholine levels in rat frontal cortex^[4].

IC 50

H₃ receptor

References

[1] Hudkins RL, et al. Discovery and characterization of 6-{4-[3-(R)-2-methylpyrrolidin-1-yl)propoxy]phenyl}-2H-pyridazin-3-one (CEP-26401, irdabisant): a potent, selective histamine H3 receptor inverse agonist. J Med Chem. 2011 Jul 14;54(13):4781-92. DOI:10.1021/jm200401v
[2] Weisler RH, et al. Randomized clinical study of a histamine H3 receptor antagonist for the treatment of adults with attention-deficit hyperactivity disorder. CNS Drugs. 2012 May 1;26(5):421-34. DOI:10.2165/11631990-000000000-00000
[3] Ghoshal A, et al. Identification of novel β-lactams and pyrrolidinone derivatives as selective Histamine-3 receptor (H3R) modulators as possible anti-obesity agents. Eur J Med Chem. 2018 May 25;152:148-159. DOI:10.1016/j.ejmech.2018.04.020
[4] Ghamari N, et al. Histamine H3 receptor antagonists/inverse agonists: Where do they go Pharmacol Ther. 2019 Aug;200:69-84. DOI:10.1016/j.pharmthera.2019.04.007

Bavisant Preparation Products And Raw materials

Raw materials

Preparation Products

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Bavisant Suppliers

China 39 United States 4 Global 43

BOC Sciences

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Jinan Mingya Medical Technology Co., Ltd.

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Bide Pharmatech Ltd.

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Shanghai Lollane Biological Technology Co.,Ltd.

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SPIRO PHARMA

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Chengdu Huachun Technology Co., Ltd

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Shanghai Rechem science Co., Ltd.

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929622-08-2, BavisantRelated Search:

Bavisant

JNJ 31001074

JNJ31001074

JNJ-31001074

Methanone, (4-cyclopropyl-1-piperazinyl)[4-(4-morpholinylmethyl)phenyl]-

JNJ31001074,JNJ 31001074,Neurological disorders,inhibit,Histamine Receptor,attention-deficit hyperactivity disorder,ADHD,cognition,Bavisant,wakefulness,Inhibitor

(4-Cyclopropylpiperazin-1-yl)(4-(morpholinomethyl)phenyl)methanone

Bavisant, 10 mM in DMSO

BEN-2001

929622-08-2