5-BroMo-4-fluoropyridin-2-aMine

Product Name: 5-BroMo-4-fluoropyridin-2-aMine
CAS No.: 944401-69-8
Chemical Name: 5-BroMo-4-fluoropyridin-2-aMine
Synonyms: 152966;5-BroMo-4-fluoropyridin-2-aMine;5-Bromo-4-fluoro-2-pyridinamine;5-bromo-4-fluoropyridine-2-amine;5-bromo-2-amino-4-fluoropyridine;2-aMino-5-broMo-4-fluoropyridine;2-Amino-4-fluoro-5-bromopyridine;2-Pyridinamine, 5-bromo-4-fluoro-;5-Bromo-4-fluoro-pyridin-2-ylamine
CBNumber: CB92629925
Molecular Formula: C5H4BrFN2
Formula Weight: 191
MOL File: 944401-69-8.mol

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5-BroMo-4-fluoropyridin-2-aMine Property

Boiling point:: 233.6±35.0 °C(Predicted)
Density: 1.813±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 4.31±0.24(Predicted)
Appearance: White to off-white Solid
InChI: InChI=1S/C5H4BrFN2/c6-3-2-9-5(8)1-4(3)7/h1-2H,(H2,8,9)
InChIKey: GGHBRLQYBZMEPV-UHFFFAOYSA-N
SMILES: C1(N)=NC=C(Br)C(F)=C1

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Safety

HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

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N-Bromosuccinimide Price

TRC

Product number: B804203
Product name: 5-bromo-4-fluoropyridin-2-amine
Packaging: 50mg
Price: $45
Updated: 2021/12/16

Apolloscientific

Product number: PC201380
Product name: 5-Bromo-4-fluoropyridin-2-amine
Purity: 95%
Packaging: 5g
Price: $250
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H30-B-0B
Product name: 5-Bromo-4-fluoropyridin-2-amine
Purity: 95%
Packaging: 1g
Price: $228
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB105195
Product name: 5-Bromo-4-fluoropyridin-2-amine
Packaging: 1g
Price: $240
Updated: 2021/12/16

Matrix Scientific

Product number: 119828
Product name: 5-Bromo-4-fluoropyridin-2-amine
Purity: 95+%
Packaging: 1g
Price: $245
Updated: 2021/12/16

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5-BroMo-4-fluoropyridin-2-aMine Chemical Properties,Usage,Production

Uses

5-BroMo-4-fluoropyridin-2-amine is a pyridine organic compound used in pharmaceutical synthesis and experiments.

Synthesis

944401-77-8

944401-69-8

A solution of 2-amino-4-fluoropyridine (75.0 g, 0.67 mol) in anhydrous acetonitrile (700 mL) was cooled in an ice-water bath under stirring conditions. Subsequently, N-bromosuccinimide (122.8 g, 0.69 mol) was added in batches. The reaction mixture was stirred continuously for 1 hour at room temperature. After completion of the reaction, the solvent was removed by evaporation under reduced pressure. The residue was washed thoroughly with water (3 x 300 mL) and then dissolved with acetonitrile and again subjected to vacuum evaporation to finally obtain 5-bromo-2-amino-4-fluoropyridine as an off-white solid (124 g, 97% yield).

References

[1] Patent: WO2015/86527, 2015, A1. Location in patent: Page/Page column 108
[2] Patent: WO2015/86526, 2015, A1. Location in patent: Page/Page column 110
[3] ACS Medicinal Chemistry Letters, 2018, vol. 9, # 7, p. 719 - 724
[4] Patent: WO2018/68283, 2018, A1. Location in patent: Paragraph 00252
[5] Patent: WO2018/68282, 2018, A1. Location in patent: Paragraph 00241

5-BroMo-4-fluoropyridin-2-aMine Preparation Products And Raw materials

Raw materials

Preparation Products

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5-BroMo-4-fluoropyridin-2-aMine Suppliers

China 103 India 1 United Kingdom 1 United States 9 Global 114

Shanghai Zhixia Chemical Technology Co., LTD

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Energy Chemical

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Chengdu HappySyn Pharmaceutical Technology Co., Ltd.

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Shanghai Topbiochem Technology Co., Ltd

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Shanghai Yolne Chemical Co., Ltd.

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View Lastest Price from 5-BroMo-4-fluoropyridin-2-aMine manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 5-bromo-4-fluoro-pyridin-2-amine 944401-69-8
Price: US $3.00-9.00/KG
Min. Order: 0.1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2025-06-26

Career Henan Chemical Co

Product: 5-BroMo-4-fluoropyridin-2-aMine 944401-69-8
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kg
Release date: 2019-12-31

944401-69-8, 5-BroMo-4-fluoropyridin-2-aMineRelated Search:

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5-bromo-4-fluoropyridine-2-amine

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944401-69-8