ChemicalBook > CAS DataBase List > 1-(4-thio-beta-D-ribofuranosyl)uracil
1-(4-thio-beta-D-ribofuranosyl)uracil
- Product Name
- 1-(4-thio-beta-D-ribofuranosyl)uracil
- CAS No.
- 6741-73-7
- Chemical Name
- 1-(4-thio-beta-D-ribofuranosyl)uracil
- Synonyms
- 4’-Thiouridine;1-(4-thio-β-D-ribofuranosyl)uracil;1-(4-thio-beta-D-ribofuranosyl)uracil;4’-Thiouridine, 1-(4-Thio-beta-D-ribofuranosyl)uracil;1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrothiophen-2-yl)pyrimidine-2,4(1H,3H)-dione
- CBNumber
- CB92630824
- Molecular Formula
- C9H12N2O5S
- Formula Weight
- 260.27
- MOL File
- 6741-73-7.mol
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1-(4-thio-beta-D-ribofuranosyl)uracil Property
- Melting point:
- 195-196 °C(Solv: chloroform (67-66-3); ethanol (64-17-5))
- Density
- 1.687±0.06 g/cm3(Predicted)
- pka
- 9.39±0.10(Predicted)
- form
- Solid
- color
- White to off-white
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N-Bromosuccinimide Price
Chemenu
- Product number
- CM167832
- Product name
- 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrothiophen-2-yl)pyrimidine-2,4(1H,3H)-dione
- Purity
- 97%
- Packaging
- 100mg
- Price
- $526
- Updated
- 2021/12/16
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1-(4-thio-beta-D-ribofuranosyl)uracil Chemical Properties,Usage,Production
Uses
4′-Thiouridine (1-(4-thio-beta-D-ribofuranosyl)uracil) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
References
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
1-(4-thio-beta-D-ribofuranosyl)uracil Preparation Products And Raw materials
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