ChemicalBook > CAS DataBase List > 1,1-Cyclobutanedicarboxylic acid, 3-oxo-, 1,1-bis(1-methylethyl) ester

1,1-Cyclobutanedicarboxylic acid, 3-oxo-, 1,1-bis(1-methylethyl) ester

Product Name
1,1-Cyclobutanedicarboxylic acid, 3-oxo-, 1,1-bis(1-methylethyl) ester
CAS No.
893724-10-2
Chemical Name
1,1-Cyclobutanedicarboxylic acid, 3-oxo-, 1,1-bis(1-methylethyl) ester
Synonyms
Diisopropyl 3-oxocyclobutane-1,1-dicarboxylate;3-Oxo-cyclobutane-1,1-dic...;Diisopropyl 3-oxocyclobutane-1,1-dicaboxylate;dipropan-2-yl 3-oxocyclobutane-1,1-dicarboxylate;1,1-bis(propan-2-yl) 3-oxocyclobutane-1,1-dicarboxylate;3-Oxo-cyclobutane-1,1-dicarboxylic acid diisopropyl ester;1,1-Cyclobutanedicarboxylic acid, 3-oxo-, 1,1-bis(1-methylethyl) ester
CBNumber
CB92631982
Molecular Formula
C12H18O5
Formula Weight
242.27
MOL File
893724-10-2.mol
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1,1-Cyclobutanedicarboxylic acid, 3-oxo-, 1,1-bis(1-methylethyl) ester Property

Boiling point:
293.2±40.0 °C(Predicted)
Density 
1.165±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
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Safety

HS Code 
2918999090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TRC
Product number
O849803
Product name
3-Oxo-cyclobutane-1,1-dicarboxylicAcidDiisopropylEster
Packaging
100mg
Price
$60
Updated
2021/12/16
AK Scientific
Product number
1474AL
Product name
1,1-Bis(propan-2-yl)3-oxocyclobutane-1,1-dicarboxylate
Packaging
1g
Price
$21
Updated
2021/12/16
SynQuest Laboratories
Product number
2229-1-33
Product name
3-Oxocyclobutane-1,1-dicarboxylic acid, diisopropyl ester
Packaging
250mg
Price
$28
Updated
2021/12/16
SynQuest Laboratories
Product number
2229-1-33
Product name
3-Oxocyclobutane-1,1-dicarboxylic acid, diisopropyl ester
Packaging
1g
Price
$83
Updated
2021/12/16
Matrix Scientific
Product number
112928
Product name
3-Oxo-cyclobutane-1,1-dicarboxylic acid diisopropyl ester
Packaging
1g
Price
$85
Updated
2021/12/16
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1,1-Cyclobutanedicarboxylic acid, 3-oxo-, 1,1-bis(1-methylethyl) ester Chemical Properties,Usage,Production

Synthesis

115118-68-8

893724-10-2

General procedure for the synthesis of diisopropyl 3-oxocyclobutane-1,1-dicarboxylate from diisopropyl 3,3-dimethoxycyclobutane-1,1-dicarboxylate: in a round-bottomed flask containing a solution of 3,3-dimethoxycyclobutane-1,1-dicarboxylic acid diisopropyl 3,3-dimethoxycyclobutane-1,1-dicarboxylate (1.5 g, 5.20 mmol) in dichloromethane (20 mL), trifluoroacetic acid (2 mL, 26.0 mmol). The reaction mixture was stirred at room temperature for 2.5 hours. After the reaction was completed, the reaction mixture was diluted with ethyl acetate. The organic phase was washed sequentially with water, saturated sodium bicarbonate solution and brine. The organic phase was dried with anhydrous sodium sulfate, filtered and concentrated to give diisopropyl 3-oxocyclobutane-1,1-dicarboxylate (1.2 g). The product was characterized by 1H NMR (400 MHz, CDCl3): δ 5.13 (dt, J = 12.5, 6.3 Hz, 2H), 3.64-3.53 (m, 4H), 1.32-1.24 (m, 12H).

References

[1] Synlett, 2009, # 11, p. 1827 - 1829
[2] Synlett, 2014, vol. 25, # 3, p. 355 - 358
[3] RSC Advances, 2016, vol. 6, # 27, p. 22737 - 22748
[4] Patent: US2009/233903, 2009, A1. Location in patent: Page/Page column 52
[5] Patent: WO2015/5901, 2015, A1. Location in patent: Page/Page column 702

1,1-Cyclobutanedicarboxylic acid, 3-oxo-, 1,1-bis(1-methylethyl) ester Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 1,1-Cyclobutanedicarboxylic acid, 3-oxo-, 1,1-bis(1-methylethyl) ester manufacturers

Career Henan Chemica Co
Product
3-Oxo-cyclobutane-1,1-dic... 893724-10-2
Price
US $1.00/g
Min. Order
1g
Purity
85.0-99.8%
Supply Ability
20 tons
Release date
2020-11-12

893724-10-2, 1,1-Cyclobutanedicarboxylic acid, 3-oxo-, 1,1-bis(1-methylethyl) esterRelated Search:


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  • Diisopropyl 3-oxocyclobutane-1,1-dicarboxylate
  • 3-Oxo-cyclobutane-1,1-dicarboxylic acid diisopropyl ester
  • Diisopropyl 3-oxocyclobutane-1,1-dicaboxylate
  • 1,1-Cyclobutanedicarboxylic acid, 3-oxo-, 1,1-bis(1-methylethyl) ester
  • dipropan-2-yl 3-oxocyclobutane-1,1-dicarboxylate
  • 3-Oxo-cyclobutane-1,1-dic...
  • 893724-10-2