(2,6-Difluoro-3,5-diMethoxyphenyl)Methanol
- Product Name
- (2,6-Difluoro-3,5-diMethoxyphenyl)Methanol
- CAS No.
- 1208434-90-5
- Chemical Name
- (2,6-Difluoro-3,5-diMethoxyphenyl)Methanol
- Synonyms
- EOS-60493;2,6-Difluoro-3,5-diMethoxybenzyl alcohol;2,6-Difluoro-3,5-dimethoxybenzenemethanol;(2,6-Difluoro-3,5-diMethoxyphenyl)Methanol;Benzenemethanol, 2,6-difluoro-3,5-dimethoxy-
- CBNumber
- CB92661365
- Molecular Formula
- C9H10F2O3
- Formula Weight
- 204.17
- MOL File
- 1208434-90-5.mol
(2,6-Difluoro-3,5-diMethoxyphenyl)Methanol Property
- storage temp.
- Sealed in dry,Room Temperature
- Appearance
- White to off-white Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- D446458
- Product name
- 2,6-Difluoro-3,5-dimethoxybenzylAlcohol
- Packaging
- 100mg
- Price
- $175
- Updated
- 2021/12/16
- Product number
- D446458
- Product name
- 2,6-Difluoro-3,5-dimethoxybenzylAlcohol
- Packaging
- 50mg
- Price
- $110
- Updated
- 2021/12/16
- Product number
- CS-0035632
- Product name
- (2,6-difluoro-3,5-dimethoxyphenyl)methanol
- Purity
- ≥99.0%
- Packaging
- 1g
- Price
- $185
- Updated
- 2021/12/16
- Product number
- CS-0035632
- Product name
- (2,6-difluoro-3,5-dimethoxyphenyl)methanol
- Purity
- ≥99.0%
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- CS-0035632
- Product name
- (2,6-difluoro-3,5-dimethoxyphenyl)methanol
- Purity
- ≥99.0%
- Packaging
- 250mg
- Price
- $95
- Updated
- 2021/12/16
(2,6-Difluoro-3,5-diMethoxyphenyl)Methanol Chemical Properties,Usage,Production
Synthesis
651734-55-3
1208434-90-5
To a solution of methyl 2,6-difluoro-3,5-dimethoxybenzoate (2.4 g, 10.3 mmol) in anhydrous THF (20 mL) was slowly added 2 M lithium borohydride in THF solution (15 mL) dropwise at 0 °C. The reaction mixture was stirred at room temperature for 48 hours. Subsequently, 2 M THF solution of lithium borohydride (2.5 mL) was added additionally and stirring was continued for 48 hours at room temperature. Upon completion of the reaction, the reaction mixture was cooled to 0 °C and quenched with saturated ammonium chloride solution (NH4Cl). The aqueous phase was extracted with ethyl acetate (3 x 20 mL). The organic phases were combined, washed with saturated saline, dried over anhydrous sodium sulfate (Na2SO4), filtered and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography to afford 2,6-difluoro-3,5-dimethoxybenzyl alcohol as a white solid (1.5 g, yield: 71.4%).1H-NMR (CDCl3, 300 MHz): δ 6.61 (t, 1H), 4.80 (d, 2H), 3.86 (s, 6H), 1.89 (brs, 1H).
References
[1] Patent: WO2016/164703, 2016, A1. Location in patent: Page/Page column 45
[2] Patent: WO2015/120049, 2015, A1. Location in patent: Page/Page column 188
[3] Patent: WO2014/144737, 2014, A1. Location in patent: Paragraph 00810
[4] Patent: US2014/142084, 2014, A1. Location in patent: Paragraph 0274
[5] Patent: US2016/199371, 2016, A1. Location in patent: Paragraph 0078; 0079
(2,6-Difluoro-3,5-diMethoxyphenyl)Methanol Preparation Products And Raw materials
Raw materials
Preparation Products
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