ChemicalBook > CAS DataBase List > MethylproaMine

MethylproaMine

Product Name: MethylproaMine
CAS No.: 188247-01-0
Chemical Name: MethylproaMine
Synonyms: MethylproaMine;Methylproamine, >99%;Methylproamine, 10 mM in DMSO;Inhibitor,Radioprotector,DNA/RNA Synthesis,Methylproamine,inhibit,DNA double-strand;Benzenamine, N,N,3-trimethyl-4-[5-(4-methyl-1-piperazinyl)[2,5'-bi-1H-benzimidazol]-2'-yl]-;N,N,3-Trimethyl-4-(5-(4-methylpiperazin-1-yl)-1H,1'H-[2,5'-bibenzo[d]imidazol]-2'-yl)aniline
CBNumber: CB92666658
Molecular Formula: C28H31N7
Formula Weight: 465.59
MOL File: 188247-01-0.mol

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MethylproaMine Property

Boiling point:: 746.8±70.0 °C(Predicted)
Density: 1.262±0.06 g/cm3(Predicted)
solubility: 25℃: DMSO
form: Powder
pka: 10.97±0.10(Predicted)
color: Light yellow to pink

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

AK Scientific

Product number: AMTBZ008
Product name: Methylproamine
Packaging: 500mg
Price: $561
Updated: 2021/12/16

DC Chemicals

Product number: DC9417
Product name: Methylproamine
Purity: >98%
Packaging: 1g
Price: $800
Updated: 2021/12/16

Crysdot

Product number: CD31002856
Product name: Methylproamine
Purity: 98+%
Packaging: 50mg
Price: $168
Updated: 2021/12/16

DC Chemicals

Product number: DC9417
Product name: Methylproamine
Purity: >98%
Packaging: 100mg
Price: $200
Updated: 2021/12/16

Crysdot

Product number: CD31002856
Product name: Methylproamine
Purity: 98+%
Packaging: 100mg
Price: $224
Updated: 2021/12/16

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MethylproaMine Chemical Properties,Usage,Production

Uses

Methylproamine is a DNA-binding radioprotector, acts by repair of transient radiation-induced oxidative species on DNA. Methylproamine also protects against ionizing radiation by preventing DNA double-strand breaks[1].

References

[1] Carl N Sprung, et al. Methylproamine protects against ionizing radiation by preventing DNA double-strand breaks. DOI:10.1016/j.mrfmmm.2010.08.005
[2] Susanne Burdak-Rothkamm, et al. Radioprotection of targeted and bystander cells by methylproamine. Strahlenther Onkol. 2015 Mar;191(3):248-55. DOI:10.1007/s00066-014-0751-9
[3] Pavel N Lobachevsky, et al. Protection by methylproamine of irradiated human keratinocytes correlates with reduction of DNA damage. Int J Radiat Biol. 2011 Mar;87(3):274-83. DOI:10.3109/09553002.2011.530333
[4] Lobachevsky PN, Vasireddy RS, Broadhurst S, Protection by methylproamine of irradiated human keratinocytes correlates with reduction of DNA damage. Int J Radiat Biol. 2011 Mar;87(3):274-83. DOI:10.3109/09553002.2011.530333
[5] Sprung CN, Vasireddy RS, Karagiannis TC, Methylproamine protects against ionizing radiation by preventing DNA double-strand breaks. Mutat Res. 2010 Oct 13;692(1-2):49-52. DOI:10.1016/j.mrfmmm.2010.08.005
[6] Martin RF, Broadhurst S, Reum ME, In vitro studies with methylproamine: a potent new radioprotector. Cancer Res. 2004 Feb 1;64(3):1067-70. DOI:10.1158/0008-5472.can-03-2423

MethylproaMine Preparation Products And Raw materials

Raw materials

Preparation Products

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188247-01-0, MethylproaMineRelated Search:

Methylproamine, >99%

MethylproaMine

Benzenamine, N,N,3-trimethyl-4-[5-(4-methyl-1-piperazinyl)[2,5'-bi-1H-benzimidazol]-2'-yl]-

Inhibitor,Radioprotector,DNA/RNA Synthesis,Methylproamine,inhibit,DNA double-strand

N,N,3-Trimethyl-4-(5-(4-methylpiperazin-1-yl)-1H,1'H-[2,5'-bibenzo[d]imidazol]-2'-yl)aniline

Methylproamine, 10 mM in DMSO

188247-01-0