ChemicalBook > CAS DataBase List > E 1210 (pharMaceutical)

E 1210 (pharMaceutical)

Product Name: E 1210 (pharMaceutical)
CAS No.: 936339-60-5
Chemical Name: E 1210 (pharMaceutical)
Synonyms: E 1210;APX 001A;Manogepix;APX001A Tosylate;E1210 ( APX001A);APX001A (E 1210);APX001 (APX 001A;Manogepix (E1210);APX001A (Manogepix;E1210, 10 mM in DMSO
CBNumber: CB92668117
Molecular Formula: C21H18N4O2
Formula Weight: 358.39
MOL File: 936339-60-5.mol

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E 1210 (pharMaceutical) Property

Boiling point:: 569.4±45.0 °C(Predicted)
Density: 1.263±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO: 100 mg/mL (279.03 mM)
pka: 5.13±0.36(Predicted)
form: Solid
color: White to light yellow
InChI: InChI=1S/C21H18N4O2/c22-21-18(4-3-11-24-21)19-13-17(25-27-19)12-15-6-8-16(9-7-15)14-26-20-5-1-2-10-23-20/h1-11,13H,12,14H2,(H2,22,24)
InChIKey: WSEKTEUGRLFBSE-UHFFFAOYSA-N
SMILES: C1(N)=NC=CC=C1C1ON=C(CC2=CC=C(COC3=NC=CC=C3)C=C2)C=1

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Hazard and Precautionary Statements (GHS)

Signal word: Warning

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N-Bromosuccinimide Price

TRC

Product number: P999733
Product name: 3-[3-[[4-[(2-Pyridinyloxy)methyl]phenyl]methyl]-5-isoxazolyl]-2-pyridinamine
Packaging: 5mg
Price: $165
Updated: 2021/12/16

ChemScene

Product number: CS-0007309
Product name: E1210
Purity: 99.30%
Packaging: 5mg
Price: $165
Updated: 2021/12/16

ChemScene

Product number: CS-0007309
Product name: E1210
Purity: 99.30%
Packaging: 10mg
Price: $300
Updated: 2021/12/16

ChemScene

Product number: CS-0007309
Product name: E1210
Purity: 99.30%
Packaging: 50mg
Price: $1320
Updated: 2021/12/16

ChemScene

Product number: CS-0007309
Product name: E1210
Purity: 99.30%
Packaging: 100mg
Price: $2250
Updated: 2021/12/16

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E 1210 (pharMaceutical) Chemical Properties,Usage,Production

Uses

3-[3-[[4-[(2-Pyridinyloxy)methyl]phenyl]methyl]-5-isoxazolyl]-2-pyridinamine is a new broad-spectrum antifungal.

in vivo

Manogepix (2.5 mg/kg, 5 mg/kg and 10 mg/kg; oral administration; twice daily; for 3 days; specific-pathogen-free female ICR mice) treatment reduces the number of viable C. albicans cells in the oral cavity in a dose-dependent manner^[2].

Animal Model:	Specific-pathogen-free female ICR mice (5 weeks; ~25 g) with C. albicans^[2]
Dosage:	2.5 mg/kg, 5 mg/kg and 10 mg/kg
Administration:	Oral administration; twice daily; for 3 days
Result:	Reduced the number of viable C. albicans cells in the oral cavity in a dose-dependent manner.

E 1210 (pharMaceutical) Preparation Products And Raw materials

Raw materials

Preparation Products

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936339-60-5, E 1210 (pharMaceutical)Related Search:

CHOLESTEROL ESTERASE

E 1210

E 1210 (pharMaceutical)

3-[3-[[4-(pyridin-2-yloxymethyl)phenyl]methyl]-1,2-oxazol-5-yl]pyridin-2-amine

APX 001A

APX001 (APX 001A

2-Pyridinamine, 3-[3-[[4-[(2-pyridinyloxy)methyl]phenyl]methyl]-5-isoxazolyl]-

E1210 ( APX001A)

APX001A Tosylate

3-[3-[[4-[(2-Pyridinyloxy)methyl]phenyl]methyl]-5-isoxazolyl]-2-pyridinamine

APX001A (E 1210)

APX001A (Manogepix

E-1210,Gwt1p,broad-spectrum,E1210,Glycosylphosphatidylinositol,inhibit,Fungal,disseminated,Inhibitor

Manogepix

Manogepix (E1210)

3-(3-(4-((Pyridin-2-yloxy)methyl)benzyl)isoxazol-5-yl)pyridin-2-amine

E1210, 10 mM in DMSO

Manogepix (E1210) ，S0491

936339-60-5