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Treprostinil intermediate

Product Name
Treprostinil intermediate
CAS No.
101692-01-7
Chemical Name
Treprostinil intermediate
Synonyms
Treprostinil Impurity;Treprostinil Descarboxy;Treprostinil Impurity 1;Treprostinil Impurity 2;Descarboxy Treprostinil;Treprostinil Impurity B;Treprostinil intermediate;(1R,2R,3aS,9aS)-2,3,3a,4,9,9a-hexahydro-1-[(3S)-3-hydroxyoctyl]-5-methoxy-1H-benz[f]inden-2-ol;(1R,2R,3aS,9aS)-1-(2-Hydroxyoctyl)-5-methoxy-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[b]naphthalen-2-ol;1H-Benz[f]indene-1-propanol, 2,3,3a,4,9,9a-hexahydro-2-hydroxy-5-methoxy-α-pentyl-, (αS,1R,2R,3aS,9aS)-
CBNumber
CB92714683
Molecular Formula
C22H34O3
Formula Weight
346.5
MOL File
101692-01-7.mol
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Treprostinil intermediate Property

Melting point:
71-72 °C
Boiling point:
509.0±50.0 °C(Predicted)
Density 
1.062±0.06 g/cm3(Predicted)
pka
15.10±0.40(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
D282095
Product name
DescarboxyTreprostinil
Packaging
2.5mg
Price
$475
Updated
2021/12/16
Crysdot
Product number
CD12187175
Product name
(1R,2R,3aS,9aS)-1-(2-Hydroxyoctyl)-5-methoxy-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[b]naphthalen-2-ol
Purity
97%
Packaging
1g
Price
$850
Updated
2021/12/16
Alichem
Product number
101692017
Product name
(1R,2R,3aS,9aS)-1-(2-Hydroxyoctyl)-5-methoxy-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[b]naphthalen-2-ol
Packaging
1g
Price
$892.5
Updated
2021/12/16
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Treprostinil intermediate Chemical Properties,Usage,Production

Uses

Descarboxy Treprostinil is an impurity in the synthesis of Treprostinil (T719500), Synthetic analog of Prostacyclin (P839060). Antihypertensive. Treprostinil, marketed under the trade name Remodulin is a medication used to treat pulmonary arterial hypertension (PAH).

Treprostinil intermediate Preparation Products And Raw materials

Raw materials

Preparation Products

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Treprostinil intermediate Suppliers

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101692-01-7, Treprostinil intermediateRelated Search:


  • Treprostinil intermediate
  • (alphaS,1R,2R,3aS,9aS)-2,3,3a,4,9,9a-Hexahydro-2-hydroxy-5-methoxy-alpha-pentyl-1H-benz[f]indene-1-propanol
  • (1R,2R,3aS,9aS)-1-(2-Hydroxyoctyl)-5-methoxy-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[b]naphthalen-2-ol
  • (1R,2R,3aS,9aS)-1-((S)-3-hydroxyoctyl)-5-methoxy-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[b]naphthalen-2-ol
  • (1R,2R,3aS,9aS)-1-((S,E)-3-hydroxyoct-1-en-1-yl)-5-methoxy-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[b]naphthalen-2-ol
  • Descarboxy Treprostinil
  • Treprostinil Impurity 2
  • Treprostinil Impurity 1
  • (1R,2R,3aS,9aS)-1-[(3S)-3-hydroxyoctyl]-5-methoxy-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[b]naphthalen-2-ol
  • Treprostinil Impurity
  • Treprostinil Descarboxy
  • 1H-Benz[f]indene-1-propanol, 2,3,3a,4,9,9a-hexahydro-2-hydroxy-5-methoxy-α-pentyl-, (αS,1R,2R,3aS,9aS)-
  • Treprostinil Impurity B
  • (alphas, 1r, 2r, 3as, 9as)-2,3,3a, 4,9,9a-hexahydro -2- hydroxy -5- methoxy -alpha- pentyl -1H- benzo [f] indene -1- propanol
  • (1R,2R,3aS,9aS)-2,3,3a,4,9,9a-hexahydro-1-[(3S)-3-hydroxyoctyl]-5-methoxy-1H-benz[f]inden-2-ol
  • 101692-01-7