ChemicalBook > CAS DataBase List > BMS-791325
BMS-791325
- Product Name
- BMS-791325
- CAS No.
- 958002-36-3
- Chemical Name
- BMS-791325
- Synonyms
- BMS-791325;BMS 791325-08;BMS-791325 1G;Beclabuvir HCl;BMS-791325 HCl;PubChem ID: 72722244;BMS 791325 hydrochloride;Beclabuvir hydrochloride;BMS-791325 Beclabuvir hydrochloride
- CBNumber
- CB92716748
- Molecular Formula
- C36H46ClN5O5S
- Formula Weight
- 696.3
- MOL File
- 958002-36-3.mol
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BMS-791325 Chemical Properties,Usage,Production
Enzyme inhibitor
This potent allosteric inhibitor (FW = 673.87 g/mol) targets hepatitis C virus NS5B polymerase IC50 <0.5 nM (biochemical assay) and EC50 = 0.8-6 nM (replicon assay). Unlike prior cyclopropyl-fused indolobenzazepine inhibitors, BMS-791325 has improved solubility and membrane permeability properties as well as reduced off-target activities, directed most notably against human pregnane X receptor (hPXR) transactivation.
BMS-791325 Preparation Products And Raw materials
Raw materials
Preparation Products
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BMS-791325 Suppliers
- Tel
- --
- Fax
- --
- sales@alsachim.com
- Country
- France
- ProdList
- 424
- Advantage
- 0