(alphaS)-alpha-[[2-(4-Morpholinyl)acetyl]amino]benzenebutanoyl-L-leucyl-L-phenylalanine methyl ester

Product Name: (alphaS)-alpha-[[2-(4-Morpholinyl)acetyl]amino]benzenebutanoyl-L-leucyl-L-phenylalanine methyl ester
CAS No.: 1140908-89-9
Chemical Name: (alphaS)-alpha-[[2-(4-Morpholinyl)acetyl]amino]benzenebutanoyl-L-leucyl-L-phenylalanine methyl ester
Synonyms: OPC-887417;Carfilzomib Impurity 36;4-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)-benzamine;methyl ((S)-2-(2-morpholinoacetamido)-4-phenylbutanoyl)-L-leucyl-L-phenylalaninate;(alphaS)-alpha [2-Morpolinyl)aceyJamnino] benzenebutanoyl-L -leucyI-L-phenylalanine methylester;L-Phenylalanine, (αS)-α-[[2-(4-Morpholinyl)acetyl]aMino]benzenebutanoyl-L-leucyl-, Methyl ester;(alphaS)-alpha-[[2-(4-Morpholinyl)acetyl]amino]benzenebutanoyl-L-leucyl-L-phenylalanine methyl ester
CBNumber: CB92717785
Molecular Formula: C32H44N4O6
Formula Weight: 580.73
MOL File: 1140908-89-9.mol

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(alphaS)-alpha-[[2-(4-Morpholinyl)acetyl]amino]benzenebutanoyl-L-leucyl-L-phenylalanine methyl ester Property

Boiling point:: 828.0±65.0 °C(Predicted)
Density: 1.158±0.06 g/cm3(Predicted)
pka: 13.29±0.46(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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(alphaS)-alpha-[[2-(4-Morpholinyl)acetyl]amino]benzenebutanoyl-L-leucyl-L-phenylalanine methyl ester Chemical Properties,Usage,Production

Uses

(S)-Methyl 2-((S)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamido)-3-phenylpropanoate is a derivative of Carfilzomib (C183460), which is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.

(alphaS)-alpha-[[2-(4-Morpholinyl)acetyl]amino]benzenebutanoyl-L-leucyl-L-phenylalanine methyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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(alphaS)-alpha-[[2-(4-Morpholinyl)acetyl]amino]benzenebutanoyl-L-leucyl-L-phenylalanine methyl ester Suppliers

China 34 India 3 United States 1 Global 38

Baiyi chemical (lianyungang) co. LTD

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Taizhou Nanfeng Pharmaceutical Research Institute

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1140908-89-9, (alphaS)-alpha-[[2-(4-Morpholinyl)acetyl]amino]benzenebutanoyl-L-leucyl-L-phenylalanine methyl esterRelated Search:

Carfilzomib Impurity 2 CarfilzoMib IMpurity 5 (S)-benzyl 2-((S)-2-((S)-2-amino-4-phenylbutanamido)-4-methylpentanamido)-3-phenylpropanoate hydrochloride (S)-N-((S)-1-(((S)-2,6-Dimethyl-3-oxohept-1-en-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide (S)-2-((S)-2-Acetamido-4-phenylbutanamido)-4-methyl-N-((S)-1-(((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)pentanamide Carfilzomib Related Impurity (S)-benzyl 2-((S)-4-methyl-2-((S)-2-(2-morpho lino acetamido)-4-phenylbutanamido)pentanamido)-3-phenylpropanoate (S)-4-Methyl-N-((S)-1-(((R)-4-Methyl-1-((R)-2-Methyloxiran-2-yl)-1-oxopentan-2-yl)aMino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-MorpholinoacetaMido)-4-phenylbutanaMido)pentanaMide (S)-2-((S)-4-Methyl-2-((R)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamido)-3-phenylpropanoic acid Carfilzomib Impurity 15 CarfilzoMib IMpurity 4 (S)-N-((S)-1-(((2R,4S)-1-((1H-Benzo[d][1,2,3]triazol-1-yl)oxy)-2-hydroxy-2,6-dimethyl-3-oxoheptan-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide Carfilzomib Impurity 9 (S)-benzyl 2-((S)-2-amino-4-methylpentanamido)-3-phenylpropanoate hydrochloride Carfilzomib Impurity 5 TFA Salt Carfilzomib Impurity 4 (N-Oxide Impurity) (R)-4-Methyl-N-((S)-1-(((S)-4-Methyl-1-((R)-2-Methyloxiran-2-yl)-1-oxopentan-2-yl)aMino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-MorpholinoacetaMido)-4-phenylbutanaMido)pentanaMide (alphaS)-alpha-Aminobenzenebutanoyl-L-leucyl-L-phenylalanine methyl ester mono(trifluoroacetate)

(alphaS)-alpha-[[2-(4-Morpholinyl)acetyl]amino]benzenebutanoyl-L-leucyl-L-phenylalanine methyl ester

L-Phenylalanine, (αS)-α-[[2-(4-Morpholinyl)acetyl]aMino]benzenebutanoyl-L-leucyl-, Methyl ester

methyl ((S)-2-(2-morpholinoacetamido)-4-phenylbutanoyl)-L-leucyl-L-phenylalaninate

Carfilzomib Impurity 36

OPC-887417

4-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)-benzamine

(alphaS)-alpha [2-Morpolinyl)aceyJamnino] benzenebutanoyl-L -leucyI-L-phenylalanine methylester

1140908-89-9

C32H44N4O6