1-[(2-Hydroxyethoxy)Methyl]adenine
- Product Name
- 1-[(2-Hydroxyethoxy)Methyl]adenine
- CAS No.
- 31383-66-1
- Chemical Name
- 1-[(2-Hydroxyethoxy)Methyl]adenine
- Synonyms
- AcycloA;9-[(2-hydroxyethoxy)methyl]adenine;1-[(2-Hydroxyethoxy)Methyl]adenine;2-[(6-Amino-9H-purin-9-yl)methoxy]ethanol;2-((6-AMino-1H-purin-1-yl)Methoxy)ethanol;Ethanol, 2-[(6-amino-9H-purin-9-yl)methoxy]-
- CBNumber
- CB92721100
- Molecular Formula
- C8H11N5O2
- Formula Weight
- 209.21
- MOL File
- 31383-66-1.mol
1-[(2-Hydroxyethoxy)Methyl]adenine Property
- storage temp.
- 2-8°C(protect from light)
- Appearance
- White to off-white Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 3562CC
- Product name
- Ethanol,2-(6-amino-9H-purin-9-yl)methoxy-
- Packaging
- 100mg
- Price
- $177
- Updated
- 2021/12/16
- Product number
- 3562CC
- Product name
- Ethanol,2-(6-amino-9H-purin-9-yl)methoxy-
- Packaging
- 250mg
- Price
- $254
- Updated
- 2021/12/16
- Product number
- 3562CC
- Product name
- Ethanol,2-(6-amino-9H-purin-9-yl)methoxy-
- Packaging
- 1g
- Price
- $531
- Updated
- 2021/12/16
- Product number
- 31383661
- Product name
- 2-((6-Amino-1H-purin-1-yl)methoxy)ethanol
- Packaging
- 1g
- Price
- $649
- Updated
- 2021/12/16
- Product number
- CM138500
- Product name
- 2-((6-Amino-1H-purin-1-yl)methoxy)ethanol
- Purity
- 95%
- Packaging
- 1g
- Price
- $757
- Updated
- 2021/12/16
1-[(2-Hydroxyethoxy)Methyl]adenine Chemical Properties,Usage,Production
Synthesis
81777-47-1
31383-66-1
General procedure for the synthesis of 2-((6-amino-1H-purin-1-yl)methoxy)ethanol from the compound (CAS: 81777-47-1): compound 15 (0.65 g, 2.4 mmol) was dissolved in saturated methanol-ammonia solution (15 mL), and the solution was transferred to a steel tube and sealed. Subsequently, the sealed steel tube was placed in an oil bath preheated to 150 °C and reacted for 24 hours. After completion of the reaction, it was cooled to room temperature, the steel tube was opened and the reaction mixture was removed. The mixture was concentrated to dryness and the resulting crude product was purified by silica gel column chromatography (eluent: dichloromethane/methanol, 90/10, v/v) to afford compound 16 in white solid form in 78% yield. The 1H-NMR (200 MHz, DMSO-d6) data of compound 16 were as follows: δ 3.46-3.53 (4H, m, 2×CH2); 4.67 (1H, t, OH); 5.55 (2H, s, OCH2N); 7.28 (2H, br s, NH2); 8.17 (1H, s, H-2); 8.27 (1H, s, H -8).ESI MS: m/z 210.1 Da [M + H]+, molecular formula C8H11N5O2, molecular weight 209.21.
References
[1] European Journal of Medicinal Chemistry, 2012, vol. 54, p. 202 - 209
1-[(2-Hydroxyethoxy)Methyl]adenine Preparation Products And Raw materials
Raw materials
Preparation Products
1-[(2-Hydroxyethoxy)Methyl]adenine Suppliers
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