[1,2,4]Triazolo[1,5-a]pyrazin-2-amine

Product Name: [1,2,4]Triazolo[1,5-a]pyrazin-2-amine
CAS No.: 88002-33-9
Chemical Name: [1,2,4]Triazolo[1,5-a]pyrazin-2-amine
Synonyms: [1,2,4]Triazolo[1,5-a]pyrazin-2-amine;2-Amino-[1,2,4]triazolo[1,5-a]pyrazine;[1,2,4]Triazolo[1,5-a]pyrazin-2-ylamine
CBNumber: CB92734836
Molecular Formula: C5H5N5
Formula Weight: 135.13
MOL File: 88002-33-9.mol

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[1,2,4]Triazolo[1,5-a]pyrazin-2-amine Property

Melting point:: 207-208 °C(Solv: 1-butanol (71-36-3))
Density: 1.74±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 2.63±0.30(Predicted)
Appearance: Off-white to light brown Solid

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Safety

HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

TRC

Product number: T796323
Product name: [1,2,4]Triazolo[1,5-a]pyrazin-2-amine
Packaging: 10mg
Price: $45
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H30-1-XP
Product name: [1,2,4]Triazolo[1,5-a]pyrazin-2-amine
Purity: 97%
Packaging: 250mg
Price: $95
Updated: 2021/12/16

Apolloscientific

Product number: OR950865
Product name: [1,2,4]triazolo[1,5-a]pyrazin-2-amine
Purity: 97%
Packaging: 1g
Price: $105
Updated: 2021/12/16

AK Scientific

Product number: 3218CU
Product name: [1,2,4]Triazolo[1,5-a]pyrazin-2-amine
Packaging: 250mg
Price: $116
Updated: 2021/12/16

AK Scientific

Product number: 3218CU
Product name: [1,2,4]Triazolo[1,5-a]pyrazin-2-amine
Packaging: 1g
Price: $188
Updated: 2021/12/16

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[1,2,4]Triazolo[1,5-a]pyrazin-2-amine Chemical Properties,Usage,Production

Synthesis

56406-73-6

88002-33-9

The general procedure for the synthesis of [1,2,4]triazolo[1,5-a]pyrazin-2-amines from the compound (CAS: 56406-73-6) is as follows: Example 270b Synthesis of [1,2,4]triazolo[1,5-a]pyrazin-2-amine 270b: In a 250 mL single-necked round-bottomed flask equipped with a magnetic stirrer and a reflux condenser, 270a (6.00 g, 26.43 mmol, 1.0 equiv), hydroxylamine hydrochloride (3.32 g, 47.52 mmol, 1.8 equiv), N,N-diisopropylethylamine (DIPEA, 12 mL), ethanol (40 mL), and methanol (40 mL) were added. The reaction mixture was stirred at 65 °C for 16 hours. Upon completion of the reaction, the mixture was cooled to room temperature and concentrated under reduced pressure to about 20 mL. The resulting suspension was collected by filtration and the solid was washed with dichloromethane/ethanol (60:1, 50 mL) to give 270b (3.3 g, 92% yield) as a white solid. Mass spectrum (MS-ESI): [M + H]+ m/z 136.3. 1H NMR (500 MHz, DMSO-d6) δ 8.84 (d, J = 1.0 Hz, 1H), 8.70 (dd, J = 1.0, 4.0 Hz, 1H), 7.98 (d, J = 5.0 Hz, 1H), 6.47 (s, 2H).

References

[1] Patent: EP2773638, 2015, B1. Location in patent: Paragraph 1093; 1095
[2] Patent: EP3252059, 2017, A1. Location in patent: Paragraph 0444; 0447; 0448
[3] Monatshefte fuer Chemie, 1983, vol. 114, p. 789 - 798

[1,2,4]Triazolo[1,5-a]pyrazin-2-amine Preparation Products And Raw materials

Raw materials

Preparation Products

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[1,2,4]Triazolo[1,5-a]pyrazin-2-amine Suppliers

China 61 India 1 United States 2 Global 64

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View Lastest Price from [1,2,4]Triazolo[1,5-a]pyrazin-2-amine manufacturers

Career Henan Chemical Co

Product: [1,2,4]Triazolo[1,5-a]pyrazin-2-amine 88002-33-9
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%HPLC
Supply Ability: 10Tons
Release date: 2020-02-19

88002-33-9, [1,2,4]Triazolo[1,5-a]pyrazin-2-amineRelated Search:

[1,2,4]Triazolo[1,5-a]pyrazin-2-amine

[1,2,4]Triazolo[1,5-a]pyrazin-2-ylamine

2-Amino-[1,2,4]triazolo[1,5-a]pyrazine

88002-33-9