ChemicalBook > CAS DataBase List > (1S,2S,3R,5S)-PinanediolN-BOC-L-phenylalanine-L-leucine boronate

(1S,2S,3R,5S)-PinanediolN-BOC-L-phenylalanine-L-leucine boronate

Product Name
(1S,2S,3R,5S)-PinanediolN-BOC-L-phenylalanine-L-leucine boronate
CAS No.
1187479-72-6
Chemical Name
(1S,2S,3R,5S)-PinanediolN-BOC-L-phenylalanine-L-leucine boronate
Synonyms
Bortezomib Impurity 53;(1S,2S,3R,5S)-PinanediolN-BOC-L-phenylalanine-L-leucine boronate;tert-butyl 4-(2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)Methyl)-benzoyl)piperazin-1-carboxylate;Carbamic acid, N-[(1S)-2-[[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]amino]-2-oxo-1-(phenylmethyl)ethyl]-, 1,1-dimethylethyl ester
CBNumber
CB92735156
Molecular Formula
C29H45BN2O5
Formula Weight
512.49
MOL File
1187479-72-6.mol
More
Less

(1S,2S,3R,5S)-PinanediolN-BOC-L-phenylalanine-L-leucine boronate Property

Boiling point:
635.7±55.0 °C(Predicted)
Density 
1.10±0.1 g/cm3(Predicted)
pka
11.39±0.46(Predicted)
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

TRC
Product number
H294360
Product name
N-[(1S)-2-[[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]amino]-2-oxo-1-(phenylmethyl)ethyl]-CarbamicAcid1,1-DimethylethylEster
Packaging
25mg
Price
$195
Updated
2021/12/16
More
Less

(1S,2S,3R,5S)-PinanediolN-BOC-L-phenylalanine-L-leucine boronate Chemical Properties,Usage,Production

Uses

N-[(1S)-2-[[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]amino]-2-oxo-1-(phenylmethyl)ethyl]-Carbamic Acid 1,1-Dimethylethyl Ester is an intermediate in the synthesis of bortezomib (B675700).Bortezomib is the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer.

(1S,2S,3R,5S)-PinanediolN-BOC-L-phenylalanine-L-leucine boronate Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

(1S,2S,3R,5S)-PinanediolN-BOC-L-phenylalanine-L-leucine boronate Suppliers

China 9 India 2 Global 11
SynZeal Research Pvt Ltd
Tel
--
Fax
--
Email
standards@synzeal.com
Country
India
ProdList
6514
Advantage
58
Pharmaffiliates Analytics and Synthetics P. Ltd
Tel
--
Fax
--
Email
mktg@pharmaffiliates.com
Country
India
ProdList
6739
Advantage
58

1187479-72-6, (1S,2S,3R,5S)-PinanediolN-BOC-L-phenylalanine-L-leucine boronateRelated Search:

Isovaleraldehyde Bortezomib Impurity 8 4,6-Methano-1,3,2-benzodioxaborole,2-[(1S)-1-chloro-3-Methylbutyl]hexahydro-3a,5,5-triMethyl-,(3aS,4S,6S,7aR)- Bortezomib Impurity 57 (R)-3-phenyl-2-(pyrazine-2-carboxaMido)propanoic acid BORTEZOMIB-PINANEDIOL Bortezomib intermediates II 3,6-Dibenzylhexahydropyrazine-2,5-dione Bortezomib Impurity 52 Bortezomib Impurity 9 Desisobutyl-n-butyl BortezoMib (IS,2S,3R,5S)-Pinanediol-L-phenylalanine-L-leucine boronate, HCl salt (S,E)-N-(1-((3-methylbut-1-en-1-yl)amino)-1-oxo-3-phenylpropan-2-yl) pyrazine-2-carboxamide Bortezomib Impurity 32 (S)-(+)-PINANEDIOL (DICHLORMETHYL)BORONATE Bortezomib Impurity 47 HCl Bortezomib Impurity 60 4,6-Methano-1,3,2-benzodioxaborole-2-methanamine

  • (1S,2S,3R,5S)-PinanediolN-BOC-L-phenylalanine-L-leucine boronate
  • tert-butyl 4-(2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)Methyl)-benzoyl)piperazin-1-carboxylate
  • Bortezomib Impurity 53
  • Carbamic acid, N-[(1S)-2-[[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]amino]-2-oxo-1-(phenylmethyl)ethyl]-, 1,1-dimethylethyl ester
  • 1187479-72-6